Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 5/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.47 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20059006 | 0.91 | AHCY (0.49) | AHCYADORA3ADORA2BHSP90B1TSHR | |
| SCHEMBL23348996 | 0.90 | AHCY (0.47) | AHCYADORA3ADORA2BHSP90B1TSHR | |
| SCHEMBL19778391 | 0.84 | ADORA3 (0.49) | ADORA3ADORA2BHSP90B1ADORA2AADORA1 | |
| SCHEMBL23348772 | 0.84 | HINT1 (0.48) | — | |
| SCHEMBL20058970 | 0.84 | HINT1 (0.40) | AHCYADORA3ADORA2BHSP90B1ADORA2A | |
| SCHEMBL20058620 | 0.84 | HINT1 (0.40) | AHCYADORA3ADORA2BHSP90B1ADORA2A | |
| SCHEMBL21136227 | 0.81 | AHCY (0.48) | AHCYADORA3ADORA2BHSP90B1TSHR | |
| SCHEMBL22224577 | 0.81 | AHCY (0.44) | AHCYBLM | |
| SCHEMBL26791962 | 0.79 | ADORA2A (0.57) | AHCYADORA3ADORA2BHSP90B1ADORA2A | |
| SCHEMBL20059079 | 0.78 | AHCY (0.52) | AHCYADORA3ADORA2BHSP90B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852603-B1 | D-AMINO ACID COMPOUNDS FOR LIVER DISEASE | IDENIX PHARMACEUTICALS LLC (US) | 2021-05-12 | — | — | EP | disclosed |
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |