Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.43 |
| ▸ | AHCY | P23526 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PGK2 | P07205 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977142 | 1.00 | NT5E (0.47) | NT5ELMNATP53CYP2C19ADORA3 | |
| SCHEMBL23992616 | 0.89 | AHCY (0.54) | NT5ELMNACYP2C19ADORA3ADORA1 | |
| SCHEMBL13224455 | 0.88 | LMNA (0.50) | NT5ELMNATP53CYP2C19ADORA3 | |
| SCHEMBL8620546 | 0.87 | NT5E (0.49) | NT5ELMNATP53CYP2C19ADORA3 | |
| SCHEMBL8620551 | 0.87 | NT5E (0.49) | NT5ELMNATP53CYP2C19ADORA3 | |
| SCHEMBL18636243 | 0.85 | CYP2C19 (0.44) | CYP2C19ADORA3ADORA1SLC29A1AHCY | |
| SCHEMBL10266353 | 0.85 | ADORA3 (0.64) | CYP2C19ADORA3ADORA1PGK1PGK2 | |
| SCHEMBL23992571 | 0.85 | ADORA3 (0.64) | CYP2C19ADORA3ADORA1PGK1PGK2 | |
| SCHEMBL1287306 | 0.85 | CYP2C19 (0.44) | CYP2C19ADORA3ADORA1SLC29A1AHCY | |
| SCHEMBL15628203 | 0.85 | CYP2C19 (0.44) | CYP2C19ADORA3ADORA1SLC29A1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |