Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.59 |
| ▸ | PNP | P00491 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.58 |
| ▸ | PDE2A | O00408 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 2/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992616 | 0.89 | AHCY (0.54) | ADORA3LMNAADORA2AADORA1NT5E | |
| SCHEMBL3436977 | 0.88 | PDE4D (0.66) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL19959557 | 0.88 | PDE4D (0.66) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL3436979 | 0.88 | PDE4D (0.66) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL6294565 | 0.87 | ADORA3 (0.64) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL10060179 | 0.87 | ADORA3 (0.64) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL20059112 | 0.84 | NT5E (0.47) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL13977142 | 0.84 | NT5E (0.47) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL12154573 | 0.83 | ADORA3 (0.59) | ADORA3SMN1; SMN2ADORA2AADORA1ADORA2B | |
| SCHEMBL20333764 | 0.83 | PDE4D (0.52) | ADORA3PDE4DPDE3APNPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |