Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17689127 | 0.80 | HPGD (0.73) | HPGDKMT2APLA2G7TSHRALDH1A1 | |
| SCHEMBL6471454 | 0.79 | HPGD (0.60) | HPGDKMT2APLA2G7TSHRALDH1A1 | |
| SCHEMBL12569383 | 0.78 | HPGD (0.73) | HPGDKMT2APLA2G7TSHRALDH1A1 | |
| SCHEMBL12337417 | 0.78 | ALDH1A1 (0.61) | HPGDKMT2AALDH1A1USP2CYP2C9 | |
| SCHEMBL436090 | 0.78 | HPGD (1.00) | HPGDTSHRALDH1A1USP2MAPK1 | |
| SCHEMBL243236 | 0.78 | HPGD (1.00) | HPGDTSHRALDH1A1USP2MAPK1 | |
| SCHEMBL27929296 | 0.78 | HPGD (1.00) | HPGDTSHRALDH1A1USP2MAPK1 | |
| SCHEMBL1927946 | 0.78 | HPGD (1.00) | HPGDTSHRALDH1A1USP2MAPK1 | |
| SCHEMBL8919062 | 0.78 | HPGD (1.00) | HPGDTSHRALDH1A1USP2MAPK1 | |
| SCHEMBL10242018 | 0.77 | HPGD (0.65) | HPGDKMT2APLA2G7TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3100745-B1 | NOVEL BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC (US) | 2018-04-18 | — | — | EP | disclosed |