Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20059924 | 0.77 | ALDH1A1 (0.35) | KDM4EHPGDALDH1A1 | |
| SCHEMBL20060202 | 0.76 | KDM4E (0.34) | KDM4EPOLBDNM1HPGDALDH1A1 | |
| SCHEMBL27035889 | 0.72 | KDM4E (0.36) | KDM4EPOLBDNM1HPGDTSHR | |
| SCHEMBL27035893 | 0.69 | KDM4E (0.34) | KDM4EPOLBDNM1PAOXALDH1A1 | |
| SCHEMBL27035886 | 0.68 | KDM4E (0.36) | KDM4EPOLBDNM1TSHRPAOX | |
| SCHEMBL1176631 | 0.64 | ALDH1A1 (0.47) | KDM4EDNM1HPGDTSHRPAOX | |
| SCHEMBL20060140 | 0.64 | — | — | |
| SCHEMBL20060158 | 0.64 | TP53 (0.39) | POLB | |
| SCHEMBL20059919 | 0.63 | MEN1 (0.35) | ALDH1A1 | |
| SCHEMBL27035906 | 0.63 | ALDH1A1 (0.35) | KDM4EPOLBLMNADNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |