Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20059945 | 0.76 | DPP7 (0.35) | KDM4EPOLBALDH1A1DNM1HPGD | |
| SCHEMBL27035889 | 0.66 | KDM4E (0.36) | KDM4EPOLBHTTMEN1ALDH1A1 | |
| SCHEMBL27035893 | 0.62 | KDM4E (0.34) | KDM4EPOLBHTTMEN1ALDH1A1 | |
| SCHEMBL27035886 | 0.61 | KDM4E (0.36) | KDM4EPOLBHTTMEN1ALDH1A1 | |
| SCHEMBL1176631 | 0.61 | ALDH1A1 (0.47) | KDM4EMEN1ALDH1A1KMT2ADNM1 | |
| Hydrochloric Acid SCHEMBL538616 | 0.59 | ALDH1A1 (0.47) | KDM4EHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL4717223 | 0.59 | KDM4E (0.44) | KDM4EPOLBALDH1A1DNM1HPGD | |
| SCHEMBL427283 | 0.59 | KDM4E (0.61) | KDM4EPOLBHTTMEN1ALDH1A1 | |
| SCHEMBL7305937 | 0.57 | DNM1 (0.52) | KDM4EPOLBHTTMEN1ALDH1A1 | |
| SCHEMBL10046070 | 0.57 | DNM1 (0.43) | KDM4EPOLBALDH1A1DNM1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |