Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20059919 | 0.85 | MEN1 (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL20059924 | 0.82 | ALDH1A1 (0.35) | ALDH1A1HPGDHTTGAASMN1; SMN2 | |
| SCHEMBL20060189 | 0.81 | MEN1 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL20060199 | 0.80 | ALDH1A1 (0.33) | ALDH1A1HPGDHTTGAASMN1; SMN2 | |
| SCHEMBL20060170 | 0.77 | CNR2 (0.34) | ALDH1A1HPGDHTTGAASMN1; SMN2 | |
| SCHEMBL20060184 | 0.76 | MEN1 (0.30) | ALDH1A1MEN1KMT2A | |
| SCHEMBL20060163 | 0.76 | MEN1 (0.30) | ALDH1A1MEN1KMT2A | |
| SCHEMBL20060209 | 0.74 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL20060005 | 0.67 | — | — | |
| SCHEMBL20059913 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |