Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12716868 | 0.82 | CARM1 (0.35) | CARM1PRMT6PRMT8 | |
| SCHEMBL19936808 | 0.82 | TMEM97 (0.33) | SIGMAR1TMEM97ALOX15 | |
| SCHEMBL19936909 | 0.82 | TMEM97 (0.33) | SIGMAR1TMEM97ALOX15 | |
| SCHEMBL10191540 | 0.81 | TMEM97 (0.31) | SIGMAR1TMEM97 | |
| SCHEMBL12458621 | 0.81 | TMEM97 (0.31) | SIGMAR1TMEM97 | |
| SCHEMBL12718026 | 0.79 | — | — | |
| SCHEMBL15444856 | 0.76 | NCF1 (0.39) | SIGMAR1TMEM97 | |
| SCHEMBL12422031 | 0.73 | KDM4E (0.42) | — | |
| SCHEMBL12716844 | 0.73 | KDM4E (0.42) | — | |
| SCHEMBL8379424 | 0.73 | KDM4E (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |