Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20060142 | 0.81 | SIGMAR1 (0.33) | TMEM97SIGMAR1 | |
| SCHEMBL19936909 | 0.79 | TMEM97 (0.33) | TMEM97SIGMAR1 | |
| SCHEMBL19936808 | 0.79 | TMEM97 (0.33) | TMEM97SIGMAR1 | |
| SCHEMBL10191535 | 0.78 | KDM4E (0.34) | — | |
| SCHEMBL12458621 | 0.78 | TMEM97 (0.31) | TMEM97SIGMAR1 | |
| SCHEMBL8435896 | 0.74 | NCF1 (0.38) | SIGMAR1 | |
| SCHEMBL10191534 | 0.73 | LTA4H (0.34) | — | |
| SCHEMBL15444856 | 0.73 | NCF1 (0.39) | TMEM97SIGMAR1 | |
| SCHEMBL24718638 | 0.71 | LTA4H (0.33) | — | |
| SCHEMBL24717530 | 0.71 | LTA4H (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735386-B2 | Aminopyrazoloquinazolines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-27 | — | — | US | disclosed |
| WO-2012010704-A1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-26 | — | — | WO | disclosed |