Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19936808 | 1.00 | TMEM97 (0.33) | TMEM97SIGMAR1ALOX15 | |
| SCHEMBL20060142 | 0.82 | SIGMAR1 (0.33) | TMEM97SIGMAR1ALOX15 | |
| SCHEMBL10191540 | 0.79 | TMEM97 (0.31) | TMEM97SIGMAR1 | |
| SCHEMBL12458621 | 0.79 | TMEM97 (0.31) | TMEM97SIGMAR1 | |
| SCHEMBL15444856 | 0.73 | NCF1 (0.39) | TMEM97SIGMAR1 | |
| SCHEMBL25001492 | 0.72 | SIGMAR1 (0.38) | TMEM97SIGMAR1 | |
| SCHEMBL310984 | 0.72 | SIGMAR1 (0.38) | TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL310946 | 0.71 | SIGMAR1 (0.37) | TMEM97SIGMAR1 | |
| SCHEMBL19936843 | 0.70 | KDM4E (0.42) | — | |
| SCHEMBL15442949 | 0.68 | SIGMAR1 (0.35) | TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018044808-A1 | INHIBITORS OF DUAL LEUCINE ZIPER (DLK) KINASE FOR THE TREATMENT OF DISEASE | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2018-03-08 | — | — | WO | disclosed |