Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20060143 | 0.81 | ALDH1A1 (0.36) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20060030 | 0.76 | KCNQ2 (0.37) | MEN1KMT2AALDH1A1KCNQ2POLB | |
| SCHEMBL20060177 | 0.72 | HPD (0.36) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL20060139 | 0.70 | CMA1 (0.39) | ALDH1A1HTT | |
| SCHEMBL20060020 | 0.68 | MEN1 (0.30) | MEN1KMT2AALDH1A1 | |
| SCHEMBL20060183 | 0.67 | NPC1 (0.35) | MEN1KMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL20060136 | 0.66 | MEN1 (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2049579 | 0.66 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1KCNQ2CYP1A2 | |
| SCHEMBL20059919 | 0.66 | MEN1 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL10192825 | 0.66 | LMNA (0.47) | MEN1KMT2AALDH1A1KCNQ2KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |