Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.67 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20061164 | 1.00 | SLC18A3 (0.67) | SLC18A3KDM1AMAOAMAOBEPHX1 | |
| SCHEMBL20061144 | 0.91 | SLC18A3 (0.79) | SLC18A3KDM1AMAOAMAOBEPHX1 | |
| SCHEMBL20061132 | 0.91 | SLC18A3 (0.79) | SLC18A3KDM1AMAOAMAOBEPHX1 | |
| SCHEMBL15131188 | 0.85 | PDPK1 (0.61) | SLC18A3KDM1AMAOAMAOBEPHX1 | |
| SCHEMBL22139619 | 0.84 | EPHX1 (0.64) | SLC18A3EPHX1LMNAHTTALDH1A1 | |
| SCHEMBL2115700 | 0.81 | HTT (0.63) | EPHX1LMNAHTTALDH1A1KMT2A | |
| SCHEMBL9226618 | 0.81 | EPHX1 (0.60) | SLC18A3KDM1AMAOAMAOBEPHX1 | |
| SCHEMBL3316700 | 0.78 | EPHX1 (0.50) | SLC18A3EPHX1LMNAHTTALDH1A1 | |
| SCHEMBL5270795 | 0.78 | LMNA (0.55) | EPHX1LMNAHTTALDH1A1KMT2A | |
| SCHEMBL61094 | 0.78 | PDPK1 (0.79) | EPHX1LMNAHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105477-A1 | A METHOD FOR PREPARING OPTICALLY ACTIVE CARBONYL COMPOUND | ZHEJIANG NHU COMPANY LTD. (CN) | 2018-04-19 | — | — | US | disclosed |
| US-20180105477-A1 | A METHOD FOR PREPARING OPTICALLY ACTIVE CARBONYL COMPOUND | ZHEJIANG NHU COMPANY LTD. (CN) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105477-A1 | A METHOD FOR PREPARING OPTICALLY ACTIVE CARBONYL COMPOUND | TPSD1, QDPR, TALDO1 | SLC18A3 2196/4885KDM1A 1461/4885MAOA 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.