Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fluorobenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL29268470 | 0.89 | TDP1 (0.40) | NFE2L2PLA2G1BATG4BTSHRKMT2A | |
| Fluorobenzene SCHEMBL27617521 | 0.88 | TP53 (0.45) | NFE2L2PLA2G1BATG4BACHETSHR | |
| Alcohol SCHEMBL28041790 | 0.87 | ACHE (0.53) | ACHETSHRTRPA1ALDH1A1HTR7 | |
| Fluorobenzene SCHEMBL27559273 | 0.86 | PTGS2 (0.48) | TSHRKMT2AMAPK1HSD17B10L3MBTL1 | |
| Fluorobenzene SCHEMBL9334312 | 0.85 | TDP1 (0.46) | NFE2L2PLA2G1BATG4BTSHRKMT2A | |
| Fluorobenzene SCHEMBL27600852 | 0.85 | TP53 (0.43) | NFE2L2PLA2G1BATG4BACHETSHR | |
| Fluorobenzene SCHEMBL27553303 | 0.84 | — | — | |
| Fluorobenzene SCHEMBL10439994 | 0.82 | LOXL2 (0.43) | NFE2L2TSHRKMT2AMAPK1HSD17B10 | |
| Fluorobenzene SCHEMBL27841178 | 0.82 | TP53 (0.41) | NFE2L2PLA2G1BATG4BACHETSHR | |
| Fluorobenzene SCHEMBL27339139 | 0.82 | TSHR (0.41) | NFE2L2ACHETSHRKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115772141-A | Synthetic method of aryl-containing piperidine derivative Boc piperidine 4-fluorophenylethanol | 苏州汉德创宏生化科技有限公司 | 2023-03-10 | — | — | CN | claimed |
| CN-110192294-A | LITHIUM ELECTRODE AND LITHIUM SECONDARY BATTERY COMPRISING SAME | 株式会社LG化学 | 2019-08-30 | — | — | CN | claimed |
| CN-109810572-A | Inorganic nano material prints ink and its preparation method and application | 深圳TCL工业研究院有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-101704756-B | The synthetic method of 1-(4-fluorophenyl)-2-methyl-2-propylamine | 大连九信精细化工有限公司 | 2017-12-05 | — | — | CN | claimed |
| CN-105087668-A | Method for preparing (S)-fluoro-phenyl ethanol with penicillium | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-11-25 | — | — | CN | claimed |
| CN-105039430-A | Method for producing (S)-fluobenzene ethanol through candida | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-11-11 | — | — | CN | claimed |
| CN-101704756-A | Synthesis method of 1- (4-fluorophenyl) -2-methyl-2-propylamine | DALIAN KAIFEI FINE CHEMICALS C | 2010-05-12 | — | — | CN | claimed |
| CN-122079717-A | Efficient oxygen deleting reagent and application thereof in carbon resource molecular skeleton deoxidizing reconstruction | — | 2026-05-26 | — | — | CN | disclosed |
| CN-118084634-A | Preparation method of fluorine-containing ether and fluorine-containing ether | 纯钧新材料(深圳)有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-116514880-A | Novel PNNO and PNNN chiral tetradentate ligand and application thereof in asymmetric hydrogenation | 凯特立斯（深圳）科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-115772141-A | Synthetic method of aryl-containing piperidine derivative Boc piperidine 4-fluorophenylethanol | 苏州汉德创宏生化科技有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-115772141-A | Synthetic method of aryl-containing piperidine derivative Boc piperidine 4-fluorophenylethanol | 苏州汉德创宏生化科技有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-108367410-B | Method for rejuvenating slurry of abrasive material | KONICA MINOLTA,INC. (JP) | 2019-11-01 | — | — | CN | disclosed |
| CN-1336821-A | Substituted 1-(piperidin-4-yl)-3-(aryl)-isothioureas, their prepn. and therapeutic use | PF MEDICAMENT (FR) | 2002-02-20 | — | — | CN | disclosed |
| CN-1325540-A | Polishing liquid for metal and polishing method | HITACHI CHEMICAL CO LTD (JP) | 2001-12-05 | — | — | CN | disclosed |
| CN-1300280-A | Process for the preparation of -alpha- (2, 3-dimethoxyphenyl) -1- [ 2- (4-fluorophenyl) ethyl ] -4-piperidinemethanol | HOECHST PHARMA (US) | 2001-06-20 | — | — | CN | disclosed |
| CN-1253547-A | 1,4-substituted cyclic amine derivatives | EISAI CO LTD (JP) | 2000-05-17 | — | — | CN | disclosed |
| CN-1033043-C | N-amide glucuromide glycoside antibiotic A40926 group and glycoside antibiotic A40926 | LEPETIT SPA (IT) | 1996-10-16 | — | — | CN | disclosed |
| CN-1095710-A | Enzyme Inhibitors | WELLCOME FOUND (GB) | 1994-11-30 | — | — | CN | disclosed |
| CN-86108977-A | N-amido glucuronide aglycone antibiotics A40926 family and aglycone antibiotics A40926 | — | 1988-04-27 | — | — | CN | disclosed |