Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20061786 | 0.91 | CYP2A6 (0.33) | EGFRADRA1DADRA1AALDH1A1CYP3A4 | |
| SCHEMBL20061807 | 0.91 | CYP2A6 (0.33) | EGFRADRA1DADRA1AALDH1A1CYP3A4 | |
| SCHEMBL20061789 | 0.89 | KDM4E (0.40) | EGFRKDM4EALDH1A1PKMHPGD | |
| SCHEMBL20061797 | 0.89 | CYP2A6 (0.34) | EGFRMEN1KMT2AADRA1DADRA1A | |
| SCHEMBL20061811 | 0.87 | CYP2A6 (0.33) | EGFRMEN1KMT2AADRA1DADRA1A | |
| SCHEMBL20061804 | 0.84 | EGFR (0.35) | EGFRKDM4E | |
| SCHEMBL20061795 | 0.84 | EGFR (0.32) | EGFRKDM4E | |
| SCHEMBL20061791 | 0.81 | MAPK9 (0.37) | EGFRKDM4EALDH1A1MAPTPKM | |
| SCHEMBL20061818 | 0.81 | MAPK9 (0.37) | EGFRKDM4EALDH1A1MAPTPKM | |
| SCHEMBL20061806 | 0.78 | KDM4E (0.37) | EGFRATMKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11239432-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2022-02-01 | — | — | US | disclosed |
| US-20180108848-A1 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-04-19 | — | — | US | disclosed |
| US-20180108848-A1 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11239432-B2 | Organic electroluminescent materials and devices | OCIAD1, OSBP, OCIAD2 | EGFR 3000/4885ATM 4631/4885KDM4E 4450/4885 |
| US-20180108848-A1 | Organic electroluminescent materials and devices | OSBP, OSBP2, OCIAD2 | EGFR 4403/4885ATM 4413/4885KDM4E 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.