SCHEMBL20061804

SCHEMBL20061804

c1ccc2c(c1)C1c3cc4cocc4cc3C2c2ncncc21

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EGFR P00533 3/20 0.35
PIK3CD O00329 1/20 0.31
PIK3CA P42336 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20061820 0.89 EGFR (0.30) EGFR
SCHEMBL20061809 0.89 EGFR (0.30) EGFR
SCHEMBL20061789 0.88 KDM4E (0.40) EGFRPIK3CDPIK3CAKDM4E
SCHEMBL20061793 0.87
SCHEMBL20061784 0.84 EGFR (0.38) EGFRKDM4E
SCHEMBL20061795 0.82 EGFR (0.32) EGFRKDM4E
SCHEMBL20061798 0.80 APAF1 (0.32)
SCHEMBL20061791 0.79 MAPK9 (0.37) EGFRPIK3CDPIK3CAKDM4E
SCHEMBL20061818 0.79 MAPK9 (0.37) EGFRPIK3CDPIK3CAKDM4E
SCHEMBL20061825 0.79 MEN1 (0.34) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11239432-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-01 US disclosed
US-20180108848-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-04-19 US disclosed
US-20180108848-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11239432-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 EGFR 3000/4885PIK3CD 982/4885PIK3CA 2639/4885
US-20180108848-A1 Organic electroluminescent materials and devices OSBP, OSBP2, OCIAD2 EGFR 4403/4885PIK3CD 1294/4885PIK3CA 3461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.