Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1256350 | 1.00 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL1512973 | 0.96 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL444364 | 0.92 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL20061841 | 0.87 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL7398961 | 0.87 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL5233467 | 0.86 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL5233459 | 0.86 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL13990630 | 0.86 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL12072337 | 0.86 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB | |
| SCHEMBL617770 | 0.86 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1NPC1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300454-B1 | Novel Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-21 | — | — | EP | disclosed |
| US-8623902-B2 | Microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-07 | — | — | US | disclosed |
| US-20110207781-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| EP-2300454-A1 | Novel Microbiocides | Syngenta Participations AG (CH) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009153191-A1 | Novel Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2009-12-23 | — | — | WO | disclosed |
| US-20080015146-A1 | Dpp-IV Inhibitors | SANTHERA PHARMACEUTICALS (DEUTSCHLAND) AG (DE) | 2008-01-17 | — | — | US | disclosed |
| EP-1786806-A1 | DPP-IV INHIBITORS | Santhera Pharmaceuticals (Schweiz) AG (CH) | 2007-05-23 | — | — | EP | disclosed |
| WO-2005121131-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015146-A1 | Dpp-IV Inhibitors | DPP4, DPP9, DPP3 | SMN1; SMN2 4238/4885ALDH1A1 435/4885NPC1 1084/4885 |
| US-20110207781-A1 | NOVEL MICROBIOCIDES | CD14, FPR1, MPO | SMN1; SMN2 3851/4885ALDH1A1 433/4885NPC1 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.