Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26318126 | 0.92 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL21813931 | 0.85 | MEN1 (0.41) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL7855456 | 0.85 | TDP1 (0.45) | ALDH1A1KMT2ATDP1CYP1A2HSD17B10 | |
| SCHEMBL21999479 | 0.84 | ATM (0.45) | ALDH1A1MEN1KMT2ATDP1HPGD | |
| SCHEMBL9911426 | 0.84 | ATM (0.50) | ALDH1A1MEN1KMT2ATDP1HPGD | |
| SCHEMBL20413347 | 0.83 | KDM4E (0.51) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL25481778 | 0.82 | MEN1 (0.49) | ALDH1A1MEN1KMT2ATDP1HPGD | |
| SCHEMBL20381630 | 0.80 | UGT8 (0.36) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL12708648 | 0.79 | TPSAB1 (0.51) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL7855509 | 0.79 | L3MBTL1 (0.63) | ALDH1A1USP2LMNAHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105512-A1 | SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105512-A1 | SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | TPSD1, TPSAB1, TMSB4X | PIK3CD 3108/4885ALDH1A1 2197/4885MEN1 1290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.