Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CRHBP | P24387 | 3/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | METAP2 | P50579 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30557374 | 1.00 | MAPT (0.72) | MAPTALDH1A1CRHBPCRHR2TDP1 | |
| SCHEMBL17849558 | 0.93 | MAPT (0.64) | MAPTALDH1A1CRHBPCRHR2TDP1 | |
| SCHEMBL2008393 | 0.87 | MAPT (0.60) | MAPTALDH1A1CRHBPCRHR2TDP1 | |
| SCHEMBL17849570 | 0.85 | HSD17B2 (0.66) | MAPTALDH1A1CRHBPCRHR2TDP1 | |
| SCHEMBL2004978 | 0.84 | MAPT (0.67) | MAPTALDH1A1CRHBPCRHR2TDP1 | |
| SCHEMBL11499329 | 0.83 | MAPT (0.64) | MAPTALDH1A1CRHBPCRHR2TDP1 | |
| SCHEMBL28704611 | 0.83 | MAPT (0.64) | MAPTALDH1A1CRHBPCRHR2TDP1 | |
| SCHEMBL29507647 | 0.83 | MAPT (0.69) | MAPTALDH1A1CRHBPCRHR2HSP90AA1 | |
| SCHEMBL28690955 | 0.83 | MAPT (0.64) | MAPTALDH1A1CRHBPCRHR2TDP1 | |
| SCHEMBL1138740 | 0.83 | MAPT (0.69) | MAPTALDH1A1CRHBPCRHR2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960435-B2 | Anti-cancer agents and androgen inhibition activity compound | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2011-06-14 | — | — | US | claimed |
| US-20100113600-A1 | ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-05-06 | — | — | US | claimed |
| WO-2008076918-A9 | ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND | UNIV MARYLAND (US) | 2008-08-07 | — | — | WO | claimed |
| WO-2008076918-A2 | ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2008-06-26 | — | — | WO | claimed |
| US-12427798-B2 | Heat-sensitive recording composition | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2025-09-30 | — | — | US | disclosed |
| US-20250001788-A1 | HEAT-SENSITIVE RECORDING COMPOSITION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2025-01-02 | — | — | US | disclosed |
| EP-4442468-A1 | HEAT-SENSITIVE RECORDING COMPOSITION | Nippon Kayaku Kabushiki Kaisha (JP) | 2024-10-09 | — | — | EP | disclosed |
| EP-4442467-A1 | THERMAL RECORDING COMPOSITION | Nippon Kayaku Kabushiki Kaisha (JP) | 2024-10-09 | — | — | EP | disclosed |
| US-20240326501-A1 | HEAT-SENSITIVE RECORDING COMPOSITION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2024-10-03 | — | — | US | disclosed |
| WO-2023100900-A1 | THERMAL RECORDING COMPOSITION | 日本化薬株式会社 | 2023-06-08 | — | — | WO | disclosed |
| WO-2023100902-A1 | HEAT-SENSITIVE RECORDING COMPOSITION | 日本化薬株式会社 | 2023-06-08 | — | — | WO | disclosed |
| CN-108349282-B | Thermosensitive recording material and diphenyl sulfone | 日本化药株式会社 | 2021-09-21 | — | — | CN | disclosed |
| US-10899153-B2 | Heat-sensitive recording material and diphenylsulfone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2021-01-26 | — | — | US | disclosed |
| WO-2020039601-A1 | OIL-IN-WATER TYPE EMULSION OF ACTINIC-RAY-CURABLE RESIN COMPOSITION, AND THERMAL RECORDING MATERIAL | 日本化薬株式会社 | 2020-02-27 | — | — | WO | disclosed |
| US-20180312465-A1 | Heat-Sensitive Recording Material And Diphenylsulfone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2018-11-01 | — | — | US | disclosed |
| EP-3378666-A1 | HEAT-SENSITIVE RECORDING MATERIAL AND DIPHENYLSULFONE | Nippon Kayaku Kabushiki Kaisha (JP) | 2018-09-26 | — | — | EP | disclosed |
| US-7960435-B2 | Anti-cancer agents and androgen inhibition activity compound | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2011-06-14 | — | — | US | disclosed |
| US-20100113600-A1 | ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2008076918-A9 | ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND | UNIV MARYLAND (US) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008076918-A2 | ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113600-A1 | ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND | AR, HTR3D, NR5A1 | MAPT 4558/4885ALDH1A1 763/4885CRHBP 1956/4885 |
| US-20180312465-A1 | Heat-Sensitive Recording Material And Diphenylsulfone | HSPA4L, WFS1, HSPH1 | MAPT 1276/4885ALDH1A1 536/4885CRHBP 4150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.