Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | CRHBP | P24387 | 3/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30557374 | 0.93 | MAPT (0.72) | MAPTALDH1A1TDP1CRHBPCRHR2 | |
| SCHEMBL2006238 | 0.93 | MAPT (0.72) | MAPTALDH1A1TDP1CRHBPCRHR2 | |
| SCHEMBL16187964 | 0.84 | MAPT (0.56) | MAPTALDH1A1TDP1CRHBPCRHR2 | |
| SCHEMBL2008393 | 0.84 | MAPT (0.60) | MAPTALDH1A1TDP1CRHBPCRHR2 | |
| SCHEMBL17849570 | 0.82 | HSD17B2 (0.66) | MAPTALDH1A1TDP1CRHBPCRHR2 | |
| SCHEMBL5956207 | 0.81 | LMNA (0.63) | MAPTALDH1A1TDP1CRHBPCRHR2 | |
| SCHEMBL2004978 | 0.80 | MAPT (0.67) | MAPTALDH1A1TDP1CRHBPCRHR2 | |
| SCHEMBL17849564 | 0.80 | ACLY (0.59) | MAPTALDH1A1LMNACA12CA2 | |
| SCHEMBL31681419 | 0.79 | CA2 (0.60) | MAPTALDH1A1LMNACA12CA2 | |
| SCHEMBL14877793 | 0.79 | MAPT (0.67) | MAPTALDH1A1TDP1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |