Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13344490 | 0.86 | TSHR (0.58) | TSHRHTTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL13301446 | 0.82 | ALDH1A1 (0.59) | TSHRHTTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL30399076 | 0.80 | LMNA (0.58) | TSHRHTTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL16213836 | 0.78 | TSHR (0.65) | TSHRHTTALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL7745194 | 0.77 | SMN1; SMN2 (0.59) | TSHRHTTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8293951 | 0.76 | POLB (0.66) | TSHRHTTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL13478215 | 0.76 | HTT (0.58) | TSHRHTTALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL10647581 | 0.75 | POLB (0.59) | TSHRHTTALDH1A1KDM4EKMT2A | |
| SCHEMBL16213835 | 0.75 | TSHR (0.51) | TSHRHTTALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL19618645 | 0.75 | TSHR (0.48) | TSHRHTTALDH1A1CXCR4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10220096-B2 | Injectable and stable hydrogels with dynamic properties modulated by biocompatible catalysts | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-03-05 | — | — | US | disclosed |
| US-20180104348-A1 | INJECTABLE AND STABLE HYDROGELS WITH DYNAMIC PROPERTIES MODULATED BY BIOCOMPATIBLE CATALYSTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10220096-B2 | Injectable and stable hydrogels with dynamic properties modulated by biocompatible catalysts | MMP1, F12, CD44 | TSHR 2746/4885HTT 343/4885ALDH1A1 2426/4885 |
| US-20180104348-A1 | INJECTABLE AND STABLE HYDROGELS WITH DYNAMIC PROPERTIES MODULATED BY BIOCOMPATIBLE CATALYSTS | MMP1, F12, CD44 | TSHR 2746/4885HTT 343/4885ALDH1A1 2426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.