SCHEMBL20062895

SCHEMBL20062895

CC(C)(C)c1ccc2c(c1)N(c1cccnc1)/C(=C1\N(c3cccnc3)c3ccc(C(C)(C)C)cc3N1c1cccnc1)N2c1cccnc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
MAPT P10636 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.44
KIF11 P52732 1/20 0.44
CCR9 P51686 3/20 0.40
HTT P42858 2/20 0.40
CYP2E1 P05181 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2A6 P11509 1/20 0.40
HRH3 Q9Y5N1 2/20 0.39
ELANE P08246 1/20 0.39
AR P10275 1/20 0.38
GAA P10253 1/20 0.38
RECQL P46063 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062906 0.81 KIF11 (0.43) ALDH1A1MAPTLMNAKIF11CCR9
SCHEMBL18905689 0.81 TSHR (0.38) ALDH1A1MAPTLMNAMAPK1KIF11
SCHEMBL18905680 0.81 TSHR (0.38) ALDH1A1MAPTLMNAMAPK1KIF11
SCHEMBL18783040 0.80 ALDH1A1 (0.43) ALDH1A1MAPTSMN1; SMN2LMNAMAPK1
SCHEMBL18783238 0.80 ALDH1A1 (0.43) ALDH1A1MAPTSMN1; SMN2LMNAMAPK1
SCHEMBL18905694 0.80 NOTUM (0.39) ALDH1A1KIF11ARHSD17B10NPC1
SCHEMBL20681861 0.79 KIF11 (0.44) ALDH1A1MAPTSMN1; SMN2LMNAMAPK1
SCHEMBL18783430 0.79 MAPT (0.42) ALDH1A1MAPTSMN1; SMN2LMNAMAPK1
SCHEMBL18854901 0.79 ALDH1A1 (0.45) ALDH1A1MAPTSMN1; SMN2LMNAMAPK1
SCHEMBL18783445 0.79 ALDH1A1 (0.42) ALDH1A1MAPTSMN1; SMN2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed