SCHEMBL20062906

SCHEMBL20062906

CC(C)(C)c1ccc2c(c1)N(c1ccncc1)/C(=C1\N(c3ccncc3)c3ccc(C(C)(C)C)cc3N1c1ccncc1)N2c1ccncc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.43
BCHE P06276 1/20 0.35
CCR9 P51686 1/20 0.35
HRH3 Q9Y5N1 2/20 0.35
CA9 Q16790 3/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
HPGD P15428 2/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
AR P10275 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18905684 0.86 CA9 (0.39) KIF11CA9CA12CA1HPGD
SCHEMBL18905679 0.86 CA9 (0.39) KIF11CA9CA12CA1HPGD
SCHEMBL18905680 0.83 TSHR (0.38) KIF11CA9CA12CA1HPGD
SCHEMBL18905689 0.83 TSHR (0.38) KIF11CA9CA12CA1HPGD
SCHEMBL20062895 0.81 ALDH1A1 (0.44) KIF11CCR9HRH3NPC1LMNA
SCHEMBL18905704 0.81 ALDH1A1 (0.35) CA9CA12CA1HPGDNPC1
SCHEMBL20062907 0.79 ALDH1A1 (0.36) HPGDNPC1LMNAMAPTTSHR
SCHEMBL20062918 0.79 HPGD (0.32) CA9CA12CA1HPGDTSHR
SCHEMBL18866680 0.79 KIF11 (0.42) KIF11BCHECCR9HRH3CA9
SCHEMBL18905694 0.78 NOTUM (0.39) KIF11HPGDNPC1RAB9AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed