SCHEMBL20062899

SCHEMBL20062899

Cc1ccc(N2C(=C3N(c4ccc(C)nc4)c4cc(F)c(F)cc4N3c3ccc(C)nc3)N(c3ccc(C)nc3)c3cc(F)c(F)cc32)cn1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.44
PTGS2 P35354 2/20 0.37
KCNQ3 O43525 1/20 0.36
KCNQ2 O43526 1/20 0.36
CHRNB2 P17787 1/20 0.34
CHRNA4 P43681 1/20 0.34
HSD17B3 P37058 1/20 0.33
GRM4 Q14833 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
TDO2 P48775 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SLC6A9 P48067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20681884 0.78 ELANE (0.36) ELANEPTGS2KCNQ3KCNQ2CHRNB2
SCHEMBL18905677 0.68
SCHEMBL18905714 0.68
SCHEMBL18905691 0.68 KCNH2 (0.37) NPC1RAB9ASMN1; SMN2
SCHEMBL18911778 0.68 KMT2A (0.40) NPC1RAB9ASMN1; SMN2
SCHEMBL18911689 0.68 RXRA (0.32)
SCHEMBL18905687 0.67 MGLL (0.38) ELANE
SCHEMBL20062896 0.67 ELANE (0.33) ELANE
SCHEMBL15424076 0.67 ELANE (0.45) ELANECHRNB2CHRNA4HSD17B3RAB9A
SCHEMBL20062890 0.67 TP53 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed