SCHEMBL20062920

SCHEMBL20062920

CC(C)(C)c1cc(N2/C(=C3/N(c4cc(C(C)(C)C)nc(C(C)(C)C)c4)c4ccc(-c5ccccc5)cc4N3c3cc(C(C)(C)C)nc(C(C)(C)C)c3)N(c3cc(C(C)(C)C)nc(C(C)(C)C)c3)c3cc(-c4ccccc4)ccc32)cc(C(C)(C)C)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.38
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SYK P43405 1/20 0.36
KCNQ3 O43525 1/20 0.36
KCNQ2 O43526 1/20 0.36
GAA P10253 3/20 0.35
HPGD P15428 1/20 0.35
KDM4E B2RXH2 2/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAPK14 Q16539 1/20 0.33
ATM Q13315 1/20 0.33
PTGS2 P35354 1/20 0.32
GRN P28799 1/20 0.32
SORT1 Q99523 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062915 0.85 HPGD (0.38) RAB9ALMNAALDH1A1TP53TSHR
SCHEMBL18905697 0.82 RXRB (0.38) ALDH1A1ATMRXRARXRB
SCHEMBL20062913 0.81 GAA (0.36) RAB9ALMNAALDH1A1TSHRHSD17B10
SCHEMBL20062922 0.80 GAA (0.33) RAB9ALMNAALDH1A1TP53TSHR
SCHEMBL20062918 0.79 HPGD (0.32) ALDH1A1TSHRHSD17B10GAAHPGD
SCHEMBL18905746 0.78 ALDH1A1 (0.43) LMNAALDH1A1HSD17B10GAAHPGD
SCHEMBL18911862 0.76 RXRA (0.34) RXRARXRB
SCHEMBL20062916 0.75 GAA (0.35) RAB9ALMNAALDH1A1TP53TSHR
SCHEMBL19343013 0.73 HSP90AA1 (0.45) LMNAALDH1A1HPGDMAPTATM
SCHEMBL19343014 0.72 HSP90AA1 (0.39) RAB9ALMNAALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed