SCHEMBL20062913

SCHEMBL20062913

Cc1cc(N2/C(=C3/N(c4cc(C)nc(C)c4)c4ccc(-c5ccccc5)cc4N3c3cc(C)nc(C)c3)N(c3cc(C)nc(C)c3)c3cc(-c4ccccc4)ccc32)cc(C)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
LMNA P02545 3/20 0.36
KDM4E B2RXH2 4/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
MAPT P10636 5/20 0.35
HSD17B10 Q99714 4/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
MAPK1 P28482 2/20 0.35
HTT P42858 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
AVPR1A P37288 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA2B P29275 1/20 0.35
ADORA1 P30542 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062910 0.83 CYP1A2 (0.35) GAAL3MBTL1LMNAKDM4ENPC1
SCHEMBL18905746 0.81 ALDH1A1 (0.43) GAALMNAKDM4EMAPTHSD17B10
SCHEMBL20062920 0.81 RAB9A (0.38) GAAL3MBTL1LMNAKDM4ENPC1
SCHEMBL20062892 0.79 RECQL (0.43) GAAL3MBTL1ALDH1A1KMT2A
SCHEMBL20071948 0.78
SCHEMBL18905697 0.77 RXRB (0.38) ALDH1A1HTT
SCHEMBL20681868 0.77 TSHR (0.37) GAAL3MBTL1LMNAKDM4ENPC1
SCHEMBL19343013 0.76 HSP90AA1 (0.45) LMNAMAPTALDH1A1HPGDHTT
SCHEMBL20062912 0.74 LMNA (0.33) GAALMNAKDM4ENPC1RAB9A
SCHEMBL18905721 0.74 MGLL (0.40) L3MBTL1KDM4ENPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed