SCHEMBL20062928

CC(C)(C)c1ccc2c(c1)N(c1nc(C(C)(C)C)cc(C(C)(C)C)n1)/C(=C1\N(c3nc(C(C)(C)C)cc(C(C)(C)C)n3)c3ccc(C(C)(C)C)cc3N1c1nc(C(C)(C)C)cc(C(C)(C)C)n1)N2c1nc(C(C)(C)C)cc(C(C)(C)C)n1

nearest known ligand 0.35

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	HSD17B10	Q99714	2/20	0.32

▸	ALDH1A1	P00352	1/20	0.32

▸	HPGD	P15428	1/20	0.32

▸	ALOX15	P16050	1/20	0.32

▸	TDP1	Q9NUW8	1/20	0.32

▸	TSHR	P16473	1/20	0.31

▸	MGAT2	Q10469	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20062918	0.84	HPGD (0.32)	HSD17B10ALDH1A1HPGDALOX15TDP1
SCHEMBL20062926	0.84	HCRTR1 (0.39)	HSD17B10ALDH1A1HPGDALOX15TDP1
SCHEMBL20062888	0.81	ALDH1A1 (0.30)	HSD17B10ALDH1A1HPGDALOX15TDP1
SCHEMBL20062930	0.80	HSD17B10 (0.33)	HSD17B10ALDH1A1HPGDTSHRMGAT2
SCHEMBL20062925	0.79	ALDH1A1 (0.32)	HSD17B10ALDH1A1HPGDALOX15TDP1
SCHEMBL20071768	0.79	SCN10A (0.33)	HSD17B10ALDH1A1HPGDALOX15TDP1
SCHEMBL20062886	0.77	NR1H3 (0.33)	—
SCHEMBL18905685	0.75	KCNH2 (0.36)	HSD17B10ALDH1A1HPGDALOX15TDP1
SCHEMBL20062907	0.74	ALDH1A1 (0.36)	HSD17B10ALDH1A1HPGDALOX15TDP1
SCHEMBL18905679	0.74	CA9 (0.39)	HSD17B10ALDH1A1HPGDALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20180108691-A1	ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS	CANON KABUSHIKI KAISHA (JP)	2018-04-19	—	—	US	disclosed