SCHEMBL20062930

Cc1cc2c(cc1C)N(c1nc(C(C)(C)C)cc(C(C)(C)C)n1)C(=C1N(c3nc(C(C)(C)C)cc(C(C)(C)C)n3)c3cc(C)c(C)cc3N1c1nc(C(C)(C)C)cc(C(C)(C)C)n1)N2c1nc(C(C)(C)C)cc(C(C)(C)C)n1

nearest known ligand 0.35

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	HSD17B10	Q99714	2/20	0.33

▸	KDM4E	B2RXH2	1/20	0.33

▸	GAA	P10253	1/20	0.33

▸	HPGD	P15428	1/20	0.33

▸	HMGCR	P04035	1/20	0.30

▸	MGAT2	Q10469	1/20	0.30

▸	ALDH1A1	P00352	1/20	0.30

▸	LMNA	P02545	1/20	0.30

▸	TP53	P04637	1/20	0.30

▸	TSHR	P16473	1/20	0.30

▸	RAB9A	P51151	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20062916	0.81	GAA (0.35)	HSD17B10KDM4EGAAHPGDHMGCR
SCHEMBL20062946	0.81	HRH4 (0.30)	—
SCHEMBL20062928	0.80	HSD17B10 (0.32)	HSD17B10HPGDMGAT2ALDH1A1TSHR
SCHEMBL20071766	0.78	HSD17B10 (0.33)	HSD17B10KDM4EGAAHPGDHMGCR
SCHEMBL20062945	0.76	HTT (0.34)	—
SCHEMBL20062880	0.73	GAA (0.35)	HSD17B10KDM4EGAAHPGDALDH1A1
SCHEMBL20062896	0.69	ELANE (0.33)	GAAHPGD
SCHEMBL20062921	0.68	KDM4E (0.33)	KDM4EALDH1A1RAB9A
SCHEMBL20062922	0.67	GAA (0.33)	HSD17B10KDM4EGAAHPGDALDH1A1
SCHEMBL20062926	0.66	HCRTR1 (0.39)	HSD17B10KDM4EGAAHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20180108691-A1	ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS	CANON KABUSHIKI KAISHA (JP)	2018-04-19	—	—	US	disclosed