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SCHEMBL20062925

SCHEMBL20062925

CC(C)(C)c1cnc(N2/C(=C3/N(c4ncc(C(C)(C)C)cn4)c4ccc(C(C)(C)C)cc4N3c3ncc(C(C)(C)C)cn3)N(c3ncc(C(C)(C)C)cn3)c3cc(C(C)(C)C)ccc32)nc1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.32
▸ HPGD P15428 1/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ ALOX5AP P20292 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ PKM P14618 1/20 0.30
▸ RECQL P46063 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062928 0.79 HSD17B10 (0.32) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL20062926 0.79 HCRTR1 (0.39) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL20681894 0.78 ALDH1A1 (0.33) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL20062937 0.78 ALDH1A1 (0.31) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL18905679 0.75 CA9 (0.39) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL18905684 0.75 CA9 (0.39) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL20062894 0.75 CA12 (0.35) ALDH1A1HPGDALOX15MEN1KMT2A
SCHEMBL18905704 0.74 ALDH1A1 (0.35) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL20062906 0.73 KIF11 (0.43) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL18905685 0.72 KCNH2 (0.36) ALDH1A1HPGDALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 — — US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 — — US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 — — US disclosed