Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20071990 | 0.76 | ROCK1 (0.42) | HCRTR1HCRTR2GRM4PIK3CAMTOR | |
| SCHEMBL20062942 | 0.72 | GPR84 (0.38) | SMN1; SMN2LMNATDP1 | |
| SCHEMBL20062939 | 0.71 | RPS6KA5 (0.42) | CYP17A1ROCK1SMN1; SMN2CYP1A2 | |
| SCHEMBL20062878 | 0.70 | SMN1; SMN2 (0.53) | ROCK1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL17716006 | 0.69 | MKNK1 (0.48) | HCRTR1HCRTR2GRM4PIK3CAMTOR | |
| SCHEMBL19533417 | 0.67 | CDK2 (0.67) | ROCK1 | |
| SCHEMBL23697527 | 0.67 | ALDH1A1 (0.48) | SMN1; SMN2KDM4ELMNAHTTALDH1A1 | |
| SCHEMBL21308705 | 0.67 | IDH1 (0.39) | GRM4PIK3CAMTORROCK1KDM4E | |
| SCHEMBL21554382 | 0.66 | ROCK1 (0.68) | ROCK1HTTPOLB | |
| SCHEMBL22397667 | 0.66 | ROCK1 (0.45) | HCRTR1HCRTR2GRM4CYP17A1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180108691-A1 | ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2018-04-19 | — | — | US | disclosed |