Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 10/20 | 0.37 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192672 | 0.82 | ESR1 (0.49) | ESR1KDRPLAAALDH1A1ALPG | |
| SCHEMBL20071999 | 0.77 | ESR1 (0.40) | ESR1KDRPLAAALDH1A1TSHR | |
| SCHEMBL21359724 | 0.72 | KDR (0.41) | ESR1KDRPLAATSHRKDM4E | |
| SCHEMBL6440778 | 0.71 | KMT2A (0.50) | ESR1KDRPLAAALDH1A1ALPG | |
| SCHEMBL27982363 | 0.70 | MEN1 (0.42) | ESR1KDRALDH1A1TSHRMAPT | |
| SCHEMBL15315970 | 0.68 | KDR (0.51) | KDRALDH1A1TSHRFLT1FLT4 | |
| SCHEMBL28813675 | 0.68 | KDR (0.46) | ESR1KDRALDH1A1HSD17B10FLT1 | |
| SCHEMBL1263722 | 0.67 | ESR1 (0.50) | ESR1KDRPLAAALDH1A1ALPG | |
| SCHEMBL19065614 | 0.67 | ESR1 (0.46) | ESR1KDRPLAAALDH1A1ALPG | |
| SCHEMBL786747 | 0.67 | HDAC4 (0.52) | ESR1ALDH1A1CHEK1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180108691-A1 | ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2018-04-19 | — | — | US | disclosed |