SCHEMBL28813675

SCHEMBL28813675

c1ccc(-c2ccccc2-n2ccnc2-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDR P35968 13/20 0.46
HCAR1 Q9BXC0 1/20 0.43
ALDH1A1 P00352 2/20 0.43
HTT P42858 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPK9 P45984 1/20 0.42
MAPK10 P53779 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
FLT1 P17948 1/20 0.41
FLT4 P35916 1/20 0.41
MGLL Q99685 1/20 0.41
ESR1 P03372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15315957 0.97 KDR (0.43) KDRHCAR1ALDH1A1HTTHSD17B10
SCHEMBL29187775 0.84 LMNA (0.45) HCAR1ALDH1A1HTTHSD17B10NPSR1
SCHEMBL15316042 0.83 KDR (0.42) KDRMAPK9MAPK10FLT1FLT4
SCHEMBL822887 0.82 KDR (0.41) KDRMAPK9MAPK10FLT1FLT4
SCHEMBL25564159 0.82 KDR (0.46) KDRMAPK9MAPK10FLT1FLT4
SCHEMBL15315970 0.82 KDR (0.51) KDRALDH1A1MAPK9MAPK10FLT1
SCHEMBL15315975 0.81 KDR (0.44) KDRMAPK9MAPK10
SCHEMBL27659057 0.78 P2RX4 (0.46) KDRHCAR1MAPK9MAPK10FLT1
SCHEMBL528245 0.77 MAPK9 (0.54) KDRMAPK9MAPK10FLT1FLT4
Benzene SCHEMBL27839441 0.77 MAPK9 (0.54) KDRMAPK9MAPK10FLT1FLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111164081-B Heterocyclic compound and noxious arthropod control agent containing same 住友化学株式会社 2022-08-12 CN disclosed