Pterostilbene

Pterostilbene

SCHEMBL20063

COc1cc(/C=C/c2ccc(O)cc2)cc(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 6/20 1.00
CYP1B1 Q16678 6/20 1.00
ALOX5 P09917 6/20 1.00
NQO2 P16083 5/20 1.00
PTGS2 P35354 4/20 1.00
TTR P02766 3/20 1.00
ABL1 P00519 3/20 1.00
BCR P11274 3/20 1.00
KDM4E B2RXH2 3/20 1.00
ABCB1 P08183 2/20 1.00
PTGS1 P23219 2/20 1.00
MEN1 O00255 2/20 1.00
MAPT P10636 2/20 1.00
KMT2A Q03164 2/20 1.00
NPC1 O15118 1/20 1.00
GAA P10253 1/20 1.00
MAPK1 P28482 1/20 1.00
RAB9A P51151 1/20 1.00
GFER P55789 1/20 1.00
HDAC6 Q9UBN7 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pterostilbene SCHEMBL28222684 1.00 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
Pterostilbene SCHEMBL3545782 1.00 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
Pterostilbene SCHEMBL563218 1.00 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
SCHEMBL562335 0.94 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
SCHEMBL562336 0.94 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
SCHEMBL30475363 0.94 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
Pterostilbene SCHEMBL3476941 0.93 NQO2 (0.86) CYP1A1CYP1B1ALOX5NQO2PTGS2
Pterostilbene SCHEMBL3476943 0.93 NQO2 (0.86) CYP1A1CYP1B1ALOX5NQO2PTGS2
SCHEMBL25328598 0.92 CYP1A1 (0.86) CYP1A1CYP1B1ALOX5NQO2PTGS2
SCHEMBL12535853 0.89 PTGS2 (0.80) CYP1A1CYP1B1ALOX5NQO2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6627 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144837-A1 GLP-1R AGONIST COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC (US) 2026-05-28 US claimed
CN-122075343-A Concocted pigment for scalp hairline and packaging bottle thereof 2026-05-26 CN claimed
CN-121518621-B Tumor drug evaluation method based on PBMC and prostate organoids and application thereof WUXI NO.2 PEOPLE'S HOSPITAL (CN) 2026-05-26 CN claimed
US-12636281-B2 Dietary supplements to ameliorate dietary inadequacies related to brain health or neurodegenerative diseases, and methods to design dietary supplements NEURORESERVE INC. (US) 2026-05-26 US claimed
WO-2026107510-A1 HOT-MELT ADHESIVE COMPOSITION AND METHOD OF APPLICATION BIOBOND ADHESIVES, INC. (US) 2026-05-21 WO claimed
EP-4744663-A2 SKIN COMPOSITION Eaderm Co., Ltd. (JP) 2026-05-20 EP claimed
EP-4743071-A2 DIPHENYLETHYLENE COMPOUNDS AND COMPOSITIONS THEREOF INNOVENE INC. (US) 2026-05-20 EP claimed
CN-122056786-A Lipid hybridization nanoparticle and preparation method and application thereof 上海世领制药有限公司 2026-05-19 CN claimed
CN-121337636-B Liposome with lipase responsiveness, preparation method, application and product thereof 广州科盈化妆品有限公司 2026-05-15 CN claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
CN-101028320-A Vegetable medicinal composition with hypoglycemic and hypolipidemic functions and its making method JIADEEN MEDICAL CO LTD GUANGZH (CN) 2007-09-05 CN claimed
EP-1782802-A1 COMBINED USE OF PTEROSTILBENE AND QUERCETIN FOR THE PRODUCTION OF CANCER TREATMENT MEDICAMENTS Universidad de Valencia (ES) 2007-05-09 EP claimed
WO-2006034219-A2 INACTIVATION OF MICROORGANISMS WITH MULTIDRUG RESISTANCE INHIBITORS AND PHENOTHIAZINIUMS THE GENERAL HOSPITAL CORPORATION (US) 2006-03-30 WO claimed
US-20060057231-A1 Pterostilbene as a new agonist for the peroxisome proliferator-activated receptor alpha isoform AGRICULTURE, UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF, THE 2006-03-16 US claimed
WO-2006020999-A2 PTEROSTILBENE AS A NEW AGONIST FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA ISOFORM THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2006-02-23 WO claimed
JP-2006502154-A 2006-01-19 JP claimed
US-20050271744-A1 Nutritional and therapeutic composition of an insulin sensitizer and a peptide fraction DSM IP ASSETS B.V. (NL) 2005-12-08 US claimed
EP-1534314-A1 A NUTRITIONAL AND THERAPEUTIC COMPOSITION OF AN INSULIN SENSITIZER AND A PEPTIDE FRACTION DSM IP Assets B.V. (NL) 2005-06-01 EP claimed
US-20050038125-A1 Method for the treatment of arthritis and pain N.V. NUTRICIA (NL) 2005-02-17 US claimed
WO-2004022083-A1 A NUTRITIONAL AND THERAPEUTIC COMPOSITION OF AN INSULIN SENSITIZER AND A PEPTIDE FRACTION DSM IP ASSETS B.V. (NL) 2004-03-18 WO claimed