Pterostilbene

Pterostilbene

SCHEMBL563218

COc1cc(C=Cc2ccc(O)cc2)cc(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 6/20 1.00
CYP1B1 Q16678 6/20 1.00
ALOX5 P09917 6/20 1.00
NQO2 P16083 5/20 1.00
PTGS2 P35354 4/20 1.00
TTR P02766 3/20 1.00
ABL1 P00519 3/20 1.00
BCR P11274 3/20 1.00
KDM4E B2RXH2 3/20 1.00
ABCB1 P08183 2/20 1.00
PTGS1 P23219 2/20 1.00
MEN1 O00255 2/20 1.00
MAPT P10636 2/20 1.00
KMT2A Q03164 2/20 1.00
NPC1 O15118 1/20 1.00
GAA P10253 1/20 1.00
MAPK1 P28482 1/20 1.00
RAB9A P51151 1/20 1.00
GFER P55789 1/20 1.00
HDAC6 Q9UBN7 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pterostilbene SCHEMBL28222684 1.00 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
Pterostilbene SCHEMBL20063 1.00 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
Pterostilbene SCHEMBL3545782 1.00 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
SCHEMBL562335 0.94 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
SCHEMBL562336 0.94 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
SCHEMBL30475363 0.94 CYP1A1 (1.00) CYP1A1CYP1B1ALOX5NQO2PTGS2
Pterostilbene SCHEMBL3476941 0.93 NQO2 (0.86) CYP1A1CYP1B1ALOX5NQO2PTGS2
Pterostilbene SCHEMBL3476943 0.93 NQO2 (0.86) CYP1A1CYP1B1ALOX5NQO2PTGS2
SCHEMBL25328598 0.92 CYP1A1 (0.86) CYP1A1CYP1B1ALOX5NQO2PTGS2
SCHEMBL12535853 0.89 PTGS2 (0.80) CYP1A1CYP1B1ALOX5NQO2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 507 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024211130-A1 METHODS FOR MODIFYING MEIOTIC RECOMBINATION IN PLANTS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-10-10 WO claimed
US-20240263203-A1 RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES IPTECTOR ASSETS APS (DK) 2024-08-08 US claimed
WO-2024124467-A1 HYDROXYSTILBENE COMPOUND OINTMENT, USE THEREOF, AND PREPARATION METHOD THEREFOR 科笛生物医药(无锡)有限公司 2024-06-20 WO claimed
WO-2023164606-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-08-31 WO claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
EP-4142751-A1 FIBROBLAST MEDIATED EXPANSION AND AUGMENTATION OF IMMUNE REGULATORY CELLS FOR TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) Figene, LLC (US) 2023-03-08 EP claimed
EP-3906301-A1 RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES Barrit Sarl (FR) 2021-11-10 EP claimed
US-20210338558-A1 USE OF COLLAGEN BINDING DOMAINS TO DELIVER PRODUCTS TO SKIN FABIUS BIOTECHNOLOGY (US) 2021-11-04 US claimed
CN-111635389-A Hydrogen peroxide responsive compound for imaging and therapy and synthesis method thereof 中国人民解放军陆军军医大学 2020-09-08 CN claimed
WO-2020141230-A1 RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES BARRIT SARL (FR) 2020-07-09 WO claimed
WO-2010111719-A2 MELANOGENESIS INHIBITION BY 3, 5-DIMETHOXY-4'-HYDROXYSTILBENES AND COSMECEUTICAL COMPOSITIONS THEREOF SAMI LABS LIMITED (IN) 2010-09-30 WO claimed
US-20100240767-A1 Melanogenesis inhibitiuon by 3,5-dimethoxy-4'-hydroxystilbenes and cosmeceutical compositions thereof SAMI LABS LTD (IN) 2010-09-23 US claimed
US-20100204179-A1 Resveratrol complex and process for the preperation UNIÃO BRASILEIRA DE EDUCAÇÃO E ASSISTÊNCIA - MANTENEDORA DA PUCRS (BR) 2010-08-12 US claimed
EP-2178525-A1 RESVERATROL COMPLEX AND PROCESS FOR THE PREPERATION União Brasileira De Educação E Assistência - Mantenedora Da Pucrs (BR) 2010-04-28 EP claimed
US-7705188-B2 Structural modification of resveratrol: sodium resverastatin phosphate Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of the Arizona State University (US) 2010-04-27 US claimed
WO-2009118338-A2 USE OF A POLYPHENOLIC TYPE COMPOUND FOR PREVENTING OR TREATING A POLYGLUTAMINE EXPANSION NEURODEGENERATIVE DISEASE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2009-10-01 WO claimed
WO-2009012551-A1 RESVERATROL COMPLEX AND PROCESS FOR THE PREPERATION UNIÄO BRASILEIRA DE EDUCAÇAO E ASSITENCIA-MANTENEDORA DA PUCRS (BR) 2009-01-29 WO claimed
US-20080166304-A1 Inactivation of Microorganisms With Multidrug Resistance Inhibitors and Phenothiaziniums THE GENERAL HOSPITAL CORPOARTION (US) 2008-07-10 US claimed
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CELANESE EMULSIONS GMBH (DE) 2008-06-12 US claimed
WO-2006034219-A2 INACTIVATION OF MICROORGANISMS WITH MULTIDRUG RESISTANCE INHIBITORS AND PHENOTHIAZINIUMS THE GENERAL HOSPITAL CORPORATION (US) 2006-03-30 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240767-A1 Melanogenesis inhibitiuon by 3,5-dimethoxy-4'-hydroxystilbenes and cosmeceutical compositions thereof TYR, MC1R, MITF CYP1A1 620/4885CYP1B1 176/4885ALOX5 171/4885
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CBR3, CBR1, CYP3A4 CYP1A1 5/4885CYP1B1 4/4885ALOX5 251/4885
US-20210338558-A1 USE OF COLLAGEN BINDING DOMAINS TO DELIVER PRODUCTS TO SKIN COL14A1, COL2A1, COL1A1 CYP1A1 2414/4885CYP1B1 2275/4885ALOX5 4281/4885
US-20100204179-A1 Resveratrol complex and process for the preperation SI, GPR119, GYS1 CYP1A1 958/4885CYP1B1 1425/4885ALOX5 3037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.