Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988581 | 0.78 | POLB (0.50) | POLBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13985266 | 0.77 | POLB (0.49) | POLBLMNAALDH1A1SMN1; SMN2KDM4E | |
| Altretamine SCHEMBL4448907 | 0.76 | LMNA (0.61) | POLBLMNAALDH1A1SMN1; SMN2KDM4E | |
| Pentamethyl Melamine SCHEMBL38832 | 0.76 | LMNA (0.61) | POLBLMNAALDH1A1SMN1; SMN2KDM4E | |
| Pentamethyl Melamine SCHEMBL15346326 | 0.74 | LMNA (0.58) | POLBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1033226 | 0.72 | CYP1A2 (0.53) | POLBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13052601 | 0.72 | POLB (0.44) | POLBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2476635 | 0.72 | POLB (0.41) | POLBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13052626 | 0.70 | POLB (0.40) | POLBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9132750 | 0.68 | LMNA (0.55) | POLBLMNAALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105618-A1 | N-HALAMINE MELAMINE DERIVATIVES AS NOVEL DECONTAMINATION AND BIOCIDAL AGENTS | STATE OF ISRAEL PRIME MINISTER'S OFFICE ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105618-A1 | N-HALAMINE MELAMINE DERIVATIVES AS NOVEL DECONTAMINATION AND BIOCIDAL AGENTS | HNMT, CAT, TYR | POLB 1415/4885LMNA 1687/4885ALDH1A1 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.