Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20064396 | 0.89 | NPC1 (0.33) | PPARAKDM4E | |
| SCHEMBL21222362 | 0.79 | IDO1 (0.32) | — | |
| SCHEMBL21222361 | 0.79 | IDO1 (0.32) | — | |
| SCHEMBL20064291 | 0.77 | LMNA (0.43) | — | |
| SCHEMBL21222386 | 0.74 | MKNK1 (0.34) | — | |
| SCHEMBL20063982 | 0.74 | MKNK1 (0.34) | — | |
| SCHEMBL20065543 | 0.74 | — | — | |
| SCHEMBL20065481 | 0.71 | — | — | |
| SCHEMBL20064420 | 0.71 | PPARA (0.57) | PPARAKDM4E | |
| SCHEMBL20064061 | 0.70 | PDE4A (0.35) | PPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |