Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 5/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 3/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83203 | 0.84 | SLC6A2 (0.62) | HTR1ASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL69817 | 0.82 | HTR1A (0.60) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL20204758 | 0.81 | SYK (0.48) | FFAR4HTR1ASLC6A2SLC6A3EPHX2 | |
| SCHEMBL19641654 | 0.80 | PDE4A (0.48) | — | |
| SCHEMBL17123797 | 0.80 | SLC6A2 (0.57) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL2299164 | 0.79 | SLC6A2 (0.37) | HTR1ASLC6A2SLC6A3SCDGPR6 | |
| SCHEMBL26144164 | 0.79 | CSNK2A1 (0.41) | GPR6 | |
| SCHEMBL14957010 | 0.79 | SLC6A2 (0.60) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL20063995 | 0.79 | PDE4D (0.51) | — | |
| SCHEMBL7366297 | 0.78 | SYK (0.48) | FFAR4HTR1ASLC6A2SLC6A3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |