Sugi Predict

Sugi Predict / Compounds / SCHEMBL20064149

SCHEMBL20064149

SCHEMBL20064149

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc(-c5ccc6c(ccc7oc8ccccc8c76)c5)c4)c3)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 4/20 0.43
▸ PLA2G4A P47712 4/20 0.43
▸ PLA2G10 O15496 1/20 0.43
▸ PGR P06401 2/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ CYP1A2 P05177 3/20 0.40
▸ ABCG2 Q9UNQ0 2/20 0.40
▸ CYP1A1 P04798 1/20 0.40
▸ FYN P06241 1/20 0.40
▸ MAPK3 P27361 1/20 0.40
▸ AHR P35869 1/20 0.40
▸ PAX8 Q06710 1/20 0.40
▸ CASP3 P42574 1/20 0.38
▸ SENP7 Q9BQF6 1/20 0.38
▸ SENP6 Q9GZR1 1/20 0.38
▸ HCRTR1 O43613 1/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ HPGD P15428 3/20 0.38
▸ CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22880331 1.00 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10PGRL3MBTL1
SCHEMBL22880209 0.99 PGR (0.42) PLA2G2APLA2G4APLA2G10PGRL3MBTL1
SCHEMBL24275056 0.96 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10PGRL3MBTL1
SCHEMBL25660713 0.96 PGR (0.44) PLA2G2APLA2G4APLA2G10PGRL3MBTL1
SCHEMBL22880424 0.96 TDP1 (0.43) PLA2G2APLA2G4APGRL3MBTL1TDP1
SCHEMBL21456236 0.95 PGR (0.41) PLA2G2APLA2G4APLA2G10PGRL3MBTL1
SCHEMBL22879767 0.94 L3MBTL1 (0.42) PLA2G2APLA2G4APGRL3MBTL1TDP1
SCHEMBL25660682 0.94 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10PGRL3MBTL1
SCHEMBL24275472 0.93 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10PGRL3MBTL1
SCHEMBL23512022 0.93 PGR (0.43) PLA2G2APLA2G4APLA2G10PGRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10741769-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-08-11 — — US disclosed
US-20180108847-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-04-19 — — US disclosed
US-20180108847-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-04-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180108847-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device NR2E3, NR0B1, NR2E1 PLA2G2A 3756/4885PLA2G4A 4121/4885PLA2G10 3884/4885
US-10741769-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device NR2E3, NR0B1, NR2E1 PLA2G2A 3756/4885PLA2G4A 4121/4885PLA2G10 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.