Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.37 |
| ▸ | ADH1A | P07327 | 4/20 | 0.37 |
| ▸ | HPGDS | O60760 | 2/20 | 0.35 |
| ▸ | ADH1C | P00326 | 3/20 | 0.34 |
| ▸ | ADH7 | P40394 | 2/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20064684 | 0.76 | ADH1B (0.42) | ADH1BADH1AHPGDSADH1CADH7 | |
| SCHEMBL20065264 | 0.76 | HPGDS (0.33) | HPGDS | |
| SCHEMBL24716629 | 0.74 | ADH1B (0.44) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL19872341 | 0.70 | ADH1B (0.44) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL23573330 | 0.69 | ADH1B (0.39) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL19020952 | 0.69 | — | — | |
| SCHEMBL18987914 | 0.67 | — | — | |
| SCHEMBL19872374 | 0.67 | ADH1B (0.41) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL19436690 | 0.65 | TRPA1 (0.33) | — | |
| SCHEMBL16412698 | 0.64 | ADH1B (0.42) | ADH1BADH1AADH1CADH7ADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |