Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21227941 | 0.90 | TRPV1 (0.39) | SCN9ATRPV1MALT1 | |
| SCHEMBL20065141 | 0.87 | TRPV1 (0.40) | SCN9ATRPV1 | |
| SCHEMBL20065597 | 0.85 | HRH3 (0.34) | MALT1 | |
| SCHEMBL21221932 | 0.84 | SCN9A (0.39) | SCN9AMALT1RBP4 | |
| SCHEMBL20064449 | 0.80 | MALT1 (0.35) | SCN9AMALT1 | |
| SCHEMBL21222066 | 0.79 | TRPV1 (0.39) | SCN9ATRPV1 | |
| SCHEMBL21227914 | 0.78 | OXTR (0.35) | SCN9ARBP4 | |
| SCHEMBL21222185 | 0.77 | TRPV1 (0.36) | SCN9ATRPV1MALT1 | |
| SCHEMBL21222188 | 0.77 | TRPV1 (0.36) | SCN9ATRPV1MALT1 | |
| SCHEMBL21227945 | 0.76 | RBP4 (0.40) | MALT1RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |