SCHEMBL20066483

SCHEMBL20066483

CC(=O)/C=C/c1ccc(Cn2ccnc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 7/20 0.78
CYP1A2 P05177 2/20 0.78
USP2 O75604 1/20 0.78
LMNA P02545 1/20 0.78
MEN1 O00255 1/20 0.78
CYP3A4 P08684 1/20 0.78
CYP2D6 P10635 1/20 0.78
CYP2C19 P33261 1/20 0.78
KMT2A Q03164 1/20 0.78
CYP19A1 P11511 6/20 0.55
CYP11B1 P15538 6/20 0.55
CYP11B2 P19099 5/20 0.55
CYP2A6 P11509 1/20 0.53
CYP2B6 P20813 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ozagrel SCHEMBL29153959 0.89 TBXAS1 (0.92) TBXAS1CYP1A2USP2LMNAMEN1
SCHEMBL28609155 0.87 TBXAS1 (0.80) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL4211 0.87 TBXAS1 (1.00) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL4210 0.87 TBXAS1 (1.00) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL582828 0.86 TBXAS1 (0.97) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL36183 0.86 TBXAS1 (1.00) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL582827 0.86 TBXAS1 (0.97) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL36182 0.86 TBXAS1 (1.00) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL1652693 0.86 TBXAS1 (0.97) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL28049244 0.86 TBXAS1 (0.97) TBXAS1CYP1A2USP2LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180104220-A1 IMIDAZOLE COMPOUND MEDSHINE DISCOVERY INC. (CN) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180104220-A1 IMIDAZOLE COMPOUND MAPT, SLC10A2, SLC5A11 TBXAS1 1000/4885CYP1A2 147/4885USP2 3356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.