Ozagrel

Ozagrel

SCHEMBL36183

Cl.O=C(O)C=Cc1ccc(Cn2ccnc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

TBXAS1

The experimentally established mechanism targets of Ozagrel. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TBXAS1 known ✓ P24557 14/20 1.00
CYP1A2 P05177 2/20 0.97
USP2 O75604 1/20 0.97
LMNA P02545 1/20 0.97
MEN1 O00255 1/20 0.97
CYP3A4 P08684 1/20 0.97
CYP2D6 P10635 1/20 0.97
CYP2C19 P33261 1/20 0.97
KMT2A Q03164 1/20 0.97
CYP19A1 P11511 1/20 0.57
CYP11B1 P15538 1/20 0.55
CYP11B2 P19099 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ozagrel SCHEMBL36182 1.00 TBXAS1 (1.00) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL10493930 0.99 TBXAS1 (0.97) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL27808192 0.99 TBXAS1 (0.97) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL10493936 0.99 TBXAS1 (0.97) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL4210 0.99 TBXAS1 (1.00) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL4211 0.99 TBXAS1 (1.00) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL582828 0.97 TBXAS1 (0.97) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL582827 0.97 TBXAS1 (0.97) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL1652693 0.97 TBXAS1 (0.97) TBXAS1CYP1A2USP2LMNAMEN1
Ozagrel SCHEMBL28049244 0.97 TBXAS1 (0.97) TBXAS1CYP1A2USP2LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 923 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843529-B Resolution method of ozagrel hydrochloride intermediate and preparation method of ozagrel hydrochloride Beijing Sunshine Nuohe Pharmaceutical Research Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-119818454-A Ozagrel hydrochloride capsule and preparation method thereof 杭州华东医药集团新药研究院有限公司 2025-04-15 CN claimed
CN-118206580-A Preparation method of ozagrel hydrochloride intermediate 山东新时代药业有限公司 2024-06-18 CN claimed
CN-117843529-A Resolution method of ozagrel hydrochloride intermediate and preparation method of ozagrel hydrochloride 北京阳光诺和药物研究股份有限公司 2024-04-09 CN claimed
CN-107735401-B Substituted dihydropyrrolopyrazole derivatives 宇部兴产株式会社 2021-08-31 CN claimed
US-10273252-B2 Substituted dihydropyrrolopyrazole derivative UBE INDUSTRIES, LTD. (JP) 2019-04-30 US claimed
US-20180186818-A1 SUBSTITUTED DIHYDROPYRROLOPYRAZOLE DERIVATIVE UBE INDUSTRIES, LTD. (JP) 2018-07-05 US claimed
EP-3309163-A1 SUBSTITUTED DIHYDROPYRROLOPYRAZOLE DERIVATIVE UBE Industries, Ltd. (JP) 2018-04-18 EP claimed
CN-106380448-A Preparation method of ozagrel 扬子江药业集团江苏海慈生物药业有限公司 2017-02-08 CN claimed
CN-102626388-B Liposome solid preparation of ozagrel HAINAN YONGTIAN DRUG RES INST CO LTD 2013-05-29 CN claimed
CN-103006644-A Method for preventing and treating thrombogenesis BEIJING FUKANGREN BIOPHARMACEUTICAL TECHNOLOGY CO LTD 2013-04-03 CN claimed
EP-1010435-B1 NANOCAPSULE PREPARATIONS FOR TREATING INTRAARTICULAR DISEASES MARUHO K K (JP) 2010-11-03 EP claimed
EP-1242068-A4 ENDOGENOUS NITRIC OXIDE SYNTHESIS UNDER CONDITIONS OF LOW OXYGEN TENSION NITROMED INC (US) 2007-04-25 EP claimed
US-20030050305-A1 Thromboxane inhibitors, compositions and methods of use NITROMED, INC. 2003-03-13 US claimed
EP-1242068-A1 ENDOGENOUS NITRIC OXIDE SYNTHESIS UNDER CONDITIONS OF LOW OXYGEN TENSION Nitromed, Inc. (US) 2002-09-25 EP claimed
WO-2001089519-A1 THROMBOXANE INHIBITORS, COMPOSITIONS AND METHODS OF USE RELATED APPLICATIONS NITROMED, INC. (US) 2001-11-29 WO claimed
WO-2001032167-A1 ENDOGENOUS NITRIC OXIDE SYNTHESIS UNDER CONDITIONS OF LOW OXYGEN TENSION NITROMED, INC. (US) 2001-05-10 WO claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed
EP-0058079-B1 4-(1-IMIDAZOLYLMETHYL)CINNAMIC ACID HYDROCHLORIDE MONOHYDRATE, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Kissei Pharmaceutical Co. Ltd. (JP) 1985-01-23 EP claimed
JP-57131769-A None JP disclosed
CN-117843529-B Resolution method of ozagrel hydrochloride intermediate and preparation method of ozagrel hydrochloride Beijing Sunshine Nuohe Pharmaceutical Research Co.,Ltd. (CN) 2026-05-26 CN disclosed
CN-117843529-B Resolution method of ozagrel hydrochloride intermediate and preparation method of ozagrel hydrochloride Beijing Sunshine Nuohe Pharmaceutical Research Co.,Ltd. (CN) 2026-05-26 CN disclosed
CN-117843529-B Resolution method of ozagrel hydrochloride intermediate and preparation method of ozagrel hydrochloride Beijing Sunshine Nuohe Pharmaceutical Research Co.,Ltd. (CN) 2026-05-26 CN disclosed
US-12629379-B2 Pharmaceutical composition for preventing, suppressing, or treating symptom associated with allergic reaction NIPPON CHEMIPHAR CO., LTD. (JP) 2026-05-19 US disclosed
US-20260042788-A1 STAT6 COMPOUNDS GILEAD SCIENCES INC (US) 2026-02-12 US disclosed
US-20260014147-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2026-01-15 US disclosed
CN-121287630-A Preparation containing ozagrel hydrochloride and preparation method thereof 北京新领先医药科技发展有限公司 2026-01-09 CN disclosed
CN-121287630-A Preparation containing ozagrel hydrochloride and preparation method thereof 北京新领先医药科技发展有限公司 2026-01-09 CN disclosed
US-20260001893-A1 SMALL MOLECULE MODULATORS OF STAT6 GILEAD SCIENCES INC (US) 2026-01-01 US disclosed
US-20260000678-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING, SUPPRESSING, OR TREATING SYMPTOM ASSOCIATED WITH PSEUDO-ALLERGIC REACTION TAKASAKI UNIV OF HEALTH AND WELFARE (JP) 2026-01-01 US disclosed
CN-121194965-A Amorphous and crystalline forms of ozagrel hydrochloride 奎米卡新特缇卡股份有限公司 2025-12-23 CN disclosed
CN-121194965-A Amorphous and crystalline forms of ozagrel hydrochloride 奎米卡新特缇卡股份有限公司 2025-12-23 CN disclosed
US-12485088-B2 Rapidly-orodispersible tablets having an interior cavity Aprecia Pharmaceuticals LLC (US) 2025-12-02 US disclosed
US-20250340551-A1 SMALL MOLECULE MODULATORS OF STAT6 GILEAD SCIENCES INC (US) 2025-11-06 US disclosed
US-20250325677-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-23 US disclosed
US-20250320205-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-16 US disclosed
US-20250320206-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-16 US disclosed
US-20250197401-A1 PURINONE DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2025-06-19 US disclosed
US-12324856-B2 Oral drug dosage form comprising drug in the form of nanoparticles Triastek, Inc. (CN) 2025-06-10 US disclosed
US-12304913-B2 Dihydropyrrolopyrazole derivative UBE INDUSTRIES, LTD. (JP) 2025-05-20 US disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
CN-119857095-A Choroidal neovascularization inhibitor or drusen inhibitor and its evaluation or screening method 林科杰诺米克斯股份有限公司 2025-04-22 CN disclosed
CN-119818454-A Ozagrel hydrochloride capsule and preparation method thereof 杭州华东医药集团新药研究院有限公司 2025-04-15 CN disclosed
CN-119818454-A Ozagrel hydrochloride capsule and preparation method thereof 杭州华东医药集团新药研究院有限公司 2025-04-15 CN disclosed
CN-119818454-A Ozagrel hydrochloride capsule and preparation method thereof 杭州华东医药集团新药研究院有限公司 2025-04-15 CN disclosed
EP-4512394-A2 DOSAGE FORMS AND USE THEREOF Triastek, Inc. (CN) 2025-02-26 EP disclosed
EP-4501357-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR SUPPRESSING OR TREATING SYMPTOMS ACCOMPANYING PSEUDO-ALLERGIC REACTIONS Takasaki University of Health and Welfare (JP) 2025-02-05 EP disclosed
US-12202829-B2 Heterocyclic compound FIMECS, INC. (JP) 2025-01-21 US disclosed
US-20240408023-A1 DOSAGE FORMS OF CONTROLLED RELEASE AT SPECIFIC GASTROINTESTINAL SITES Triastek, Inc. (CN) 2024-12-12 US disclosed
EP-4171518-B1 RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY Aprecia Pharmaceuticals LLC (US) 2024-12-11 EP disclosed
US-20240342094-A1 COMPARTMENTED PHARMACEUTICAL DOSAGE FORMS Triastek, Inc. (CN) 2024-10-17 US disclosed
EP-3302442-B1 DOSAGE FORMS AND USE THEREOF TRIASTEK INC (CN) 2024-10-16 EP disclosed
US-12102721-B2 Dosage forms of controlled release at specific gastrointestinal sites Triastek, Inc. (CN) 2024-10-01 US disclosed
US-20240317751-A1 PURINONE DERIVATIVE HYDROCHLORIDE ONO PHARMACEUTICAL CO., LTD. (JP) 2024-09-26 US disclosed
CN-118662488-A Therapeutic agent for myalgic encephalomyelitis/chronic fatigue syndrome 田边三菱制药株式会社 2024-09-20 CN disclosed
CN-114980874-B Therapeutic agent for myalgic encephalomyelitis/chronic fatigue syndrome 田边三菱制药株式会社 2024-08-13 CN disclosed
US-12042562-B2 3D printing methods for compartmented pharmaceutical dosage forms Triastek, Inc. (CN) 2024-07-23 US disclosed
CN-118206580-A Preparation method of ozagrel hydrochloride intermediate 山东新时代药业有限公司 2024-06-18 CN disclosed
CN-118206580-A Preparation method of ozagrel hydrochloride intermediate 山东新时代药业有限公司 2024-06-18 CN disclosed
CN-117924203-A Method for synthesizing ozagrel intermediate 山东新时代药业有限公司 2024-04-26 CN disclosed
CN-117924204-A Synthesis method of ozagrel intermediate 山东新时代药业有限公司 2024-04-26 CN disclosed
CN-117924264-A Preparation method of ozagrel intermediate 山东新时代药业有限公司 2024-04-26 CN disclosed
CN-111902146-B Medicinal products for treating cough 日本化学药品株式会社 2024-04-12 CN disclosed
CN-117843529-A Resolution method of ozagrel hydrochloride intermediate and preparation method of ozagrel hydrochloride 北京阳光诺和药物研究股份有限公司 2024-04-09 CN disclosed
CN-117843529-A Resolution method of ozagrel hydrochloride intermediate and preparation method of ozagrel hydrochloride 北京阳光诺和药物研究股份有限公司 2024-04-09 CN disclosed
CN-117843529-A Resolution method of ozagrel hydrochloride intermediate and preparation method of ozagrel hydrochloride 北京阳光诺和药物研究股份有限公司 2024-04-09 CN disclosed
US-20240083899-A1 PURINONE DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2024-03-14 US disclosed
US-11897885-B2 Purinone derivative hydrochloride ONO PHARMACEUTICAL CO., LTD. (JP) 2024-02-13 US disclosed
EP-4306524-A2 LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS PureTech LYT, Inc. (US) 2024-01-17 EP disclosed
US-11851449-B2 Heterocyclic amide compounds having an RORvt inhibitory action TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-12-26 US disclosed
EP-3750540-B1 CHOROIDAL NEOVASCULARIZATION SUPPRESSOR OR DRUSEN FORMATION SUPPRESSOR LINK GENOMICS INC (JP) 2023-12-13 EP disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
EP-3885347-B1 DIHYDROPYRROLOPYRAZOLE DERIVATIVE UBE CORP (JP) 2023-11-22 EP disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
CN-110997645-B Preparation method of ozagrel 埃吉斯制药公司 2023-10-10 CN disclosed
WO-2023190826-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR SUPPRESSING OR TREATING SYMPTOMS ACCOMPANYING PSEUDO-ALLERGIC REACTIONS 学校法人 高崎健康福祉大学 2023-10-05 WO disclosed
US-20230277552-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING, SUPPRESSING, OR TREATING SYMPTOM ASSOCIATED WITH ALLERGIC REACTION NIPPON CHEMIPHAR CO., LTD. (JP) 2023-09-07 US disclosed
US-20230270665-A1 RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY Aprecia Pharmaceuticals LLC 2023-08-31 US disclosed
US-20230265153-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 LTD (GB) 2023-08-24 US disclosed
US-20230242529-A1 HETEROCYCLIC COMPOUND FIMECS, INC. (JP) 2023-08-03 US disclosed
CN-116437928-A Pharmaceutical composition for preventing, inhibiting or treating symptoms associated with allergic reactions 日本化学药品株式会社 2023-07-14 CN disclosed
CN-112062785-B Preparation method of ozagrel and intermediate thereof 广东东阳光药业有限公司 2023-06-27 CN disclosed
EP-4190356-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING, SUPPRESSING, OR TREATING SYMPTOMS ASSOCIATED WITH ALLERGIC REACTION Nippon Chemiphar Co., Ltd. (JP) 2023-06-07 EP disclosed
CN-113171350-B Pharmaceutical dosage forms and uses thereof 南京三迭纪医药科技有限公司 2023-05-26 CN disclosed
EP-3590938-B1 PURINONE DERIVATIVE AS BTK KINASE INHIBITOR ONO PHARMACEUTICAL CO (JP) 2023-05-24 EP disclosed
EP-3018123-B1 AMIDE COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2023-05-10 EP disclosed
EP-4171518-A1 RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY Aprecia Pharmaceuticals LLC (US) 2023-05-03 EP disclosed
US-11639354-B2 Heterocyclic compound FIMECS, INC. (JP) 2023-05-02 US disclosed
CN-116018131-A Fast orodispersible tablet with inner cavity 阿普雷奇亚制药有限责任公司 2023-04-25 CN disclosed
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels ASCENDIS PHARMA A/S (DK) 2023-04-20 US disclosed
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels ASCENDIS PHARMA A/S (DE) 2023-01-24 US disclosed
US-11548928-B2 Engineered platelets for targeted delivery of a therapeutic agent JPV01 LTD. (GB) 2023-01-10 US disclosed
CN-115504979-A Method for synthesizing mercaptopurine 南京卡文迪许生物工程技术有限公司 2022-12-23 CN disclosed
US-20220402935-A1 HETEROCYCLIC COMPOUND FIMECS, INC. (JP) 2022-12-22 US disclosed
US-11518796-B2 Engineered platelets for targeted delivery of a therapeutic agent JPV01 LTD. (GB) 2022-12-06 US disclosed
US-11512085-B2 Heteroaryl compound having drug activity SHANGHAI DUDE MEDICAL TECHNOLOGY CO., LTD (CN) 2022-11-29 US disclosed
US-20220363684-A1 PURINONE DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2022-11-17 US disclosed
US-11433022-B2 Rapidly-orodispersible tablets having an in interior cavity Aprecia Pharmaceuticals LLC (US) 2022-09-06 US disclosed
US-20220251165-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 LTD. (GB) 2022-08-11 US disclosed
CN-113081991-B Pharmaceutical dosage forms and uses thereof 南京三迭纪医药科技有限公司 2022-07-15 CN disclosed
EP-4026898-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 Ltd (GB) 2022-07-13 EP disclosed
CN-114729004-A Heterocyclic compounds 日商泛美克斯股份有限公司 2022-07-08 CN disclosed
CN-113444099-B Reaction type hydrogen sulfide fluorescent probe and preparation and application thereof 浙江大学城市学院 2022-06-21 CN disclosed
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 EP disclosed
US-20220177474-A1 PURINONE DERIVATIVE HYDROCHLORIDE ONO PHARMACEUTICAL CO., LTD. (JP) 2022-06-09 US disclosed
EP-4006037-A1 HETEROCYCLIC COMPOUND Fimecs, Inc. (JP) 2022-06-01 EP disclosed
EP-3981392-A1 CONTROLLED RELEASE DOSAGE FORM Triastek, Inc. (CN) 2022-04-13 EP disclosed
US-11292795-B2 Purinone derivative hydrochloride ONO PHARMACEUTICAL CO., LTD. (JP) 2022-04-05 US disclosed
US-11278499-B2 Oral drug dosage form comprising various release profiles Triastek, Inc. (CN) 2022-03-22 US disclosed
US-20220073653-A1 CUBIC CYCLODEXTRIN FRAMEWORK-RGD COMPOSITION AND PREPARATION METHOD THEREFOR SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2022-03-10 US disclosed
US-20220054409-A1 RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY Aprecia Pharmaceuticals LLC 2022-02-24 US disclosed
US-11246873-B2 Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate THE SCRIPPS RESEARCH INSTITUTE (US) 2022-02-15 US disclosed
US-20220041684-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 LTD. (GB) 2022-02-10 US disclosed
EP-3947434-A2 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 Ltd (GB) 2022-02-09 EP disclosed
US-20220002303-A1 DIHYDROPYRROLOPYRAZOLE DERIVATIVE UBE CORPORATION (JP) 2022-01-06 US disclosed
WO-2021263132-A1 RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY Aprecia Pharmaceuticals LLC (US) 2021-12-30 WO disclosed
EP-3592393-B1 RELEASABLE CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2021-12-01 EP disclosed
CN-109111446-B Heteroaryl compound with pharmaceutical activity 上海度德医药科技有限公司 2021-11-30 CN disclosed
EP-3913003-A1 CUBIC CYCLODEXTRIN FRAMEWORK-RGD COMPOSITION AND PREPARATION METHOD THEREFOR Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2021-11-24 EP disclosed
EP-3885347-A1 DIHYDROPYRROLOPYRAZOLE DERIVATIVE Ube Industries, Ltd. (JP) 2021-09-29 EP disclosed
CN-113444099-A Reaction type hydrogen sulfide fluorescent probe and preparation and application thereof 浙江大学城市学院 2021-09-28 CN disclosed
US-11116849-B2 Hydrogel-linked prodrugs releasing tagged drugs ASCENDIS PHARMA A/S (DK) 2021-09-14 US disclosed
US-20210277030-A1 AMIDE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-09-09 US disclosed
CN-108653221-B Pharmaceutical dosage forms and uses thereof 南京三迭纪医药科技有限公司 2021-09-07 CN disclosed
CN-107735401-B Substituted dihydropyrrolopyrazole derivatives 宇部兴产株式会社 2021-08-31 CN disclosed
CN-111440253-B Cubic cyclodextrin framework-RGD composition and preparation method thereof 中国科学院上海药物研究所 2021-08-27 CN disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20210205226-A1 ORAL DRUG DOSAGE FORM COMPRISING DRUG IN THE FORM OF NANOPARTICLES Triastek, Inc. (CN) 2021-07-08 US disclosed
US-11053262-B2 Heterocyclic amide compounds having RORyT inhibitory action TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-07-06 US disclosed
WO-2021123775-A2 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 LTD (GB) 2021-06-24 WO disclosed
US-20210179614-A1 HETEROCYCLIC COMPOUND FIMECS, INC. (JP) 2021-06-17 US disclosed
EP-3831811-A1 HETEROCYCLIC COMPOUND Fimecs, Inc. (JP) 2021-06-09 EP disclosed
EP-3119885-B1 ANTIBODY-FYNOMER CONJUGATES MITSUBISHI TANABE PHARMA CORP (JP) 2021-06-02 EP disclosed
US-20210128479-A1 DOSAGE FORMS OF CONTROLLED RELEASE AT SPECIFIC GASTROINTESTINAL SITES Triastek, Inc. (CN) 2021-05-06 US disclosed
US-10973767-B2 Oral drug dosage form comprising drug in the form of nanoparticles Triastek, Inc. (CN) 2021-04-13 US disclosed
CN-109923101-B Cyclic compound 武田药品工业株式会社 2021-03-09 CN disclosed
CN-108721242-B Pharmaceutical dosage forms and uses thereof 南京三迭纪医药科技有限公司 2021-03-02 CN disclosed
EP-3782649-A1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS Ascendis Pharma A/S (DK) 2021-02-24 EP disclosed
CN-108026088-B Oxadiazole derivatives as HDAC inhibitors 武田药品工业株式会社 2021-02-12 CN disclosed
WO-2021020585-A1 HETEROCYCLIC COMPOUND ファイメクス株式会社 2021-02-04 WO disclosed
WO-2021020586-A1 HETEROCYCLIC COMPOUND ファイメクス株式会社 2021-02-04 WO disclosed
US-20210015933-A1 BIOACTIVE CARBOXYLIC ACID TYPE COMPOUND-POLYMER CONJUGATE, AND METHOD FOR MANUFACTURING THE SAME SEIKAGAKU CORPORATION (JP) 2021-01-21 US disclosed
US-10894798-B2 Substituted dihydropyrrolopyrazole derivative UBE INDUSTRIES, LTD. (JP) 2021-01-19 US disclosed
CN-106211782-B Antibody-fynomer conjugates 田边三菱制药株式会社 2021-01-15 CN disclosed
US-20210009593-A1 PURINONE DERIVATIVE HYDROCHLORIDE ONO PHARMACEUTICAL CO., LTD. (JP) 2021-01-14 US disclosed
US-10869851-B1 Targeting NUR77 for mitigating perinatal neuroinflammation THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2020-12-22 US disclosed
US-20200390780-A1 DIRECTED DIFFERENTIATION OF OLIGODENDROCYTE PRECURSOR CELLS TO A MYELINATING CELL FATE NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) 2020-12-17 US disclosed
EP-3750540-A1 CHOROIDAL NEOVASCULARIZATION SUPPRESSOR OR DRUSEN FORMATION SUPPRESSOR Link Genomics, Inc. (JP) 2020-12-16 EP disclosed
US-20200360391-A1 Medicinal Composition for Treating Intractable Heart Disease OSAKA UNIVERSITY (JP) 2020-11-19 US disclosed
US-10835520-B2 Phenyl derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2020-11-17 US disclosed
CN-111902146-A Medicinal product for treating cough 日本化学药品株式会社 2020-11-06 CN disclosed
US-20200339577-A1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-10-29 US disclosed
US-10807981-B2 Purinone derivative hydrochloride ONO PHARMACEUTICAL CO., LTD. (JP) 2020-10-20 US disclosed
US-20200315971-A1 3D PRINTING METHODS FOR COMPARTMENTED PHARMACEUTICAL DOSAGE FORMS Triastek, Inc. (CN) 2020-10-08 US disclosed
EP-2992086-B1 MODULATION OF REGULATORY T CELL FUNCTION VIA PROTEIN KINASE C-ETA LA JOLLA INST ALLERGY & IMMUNOLOGY (US) 2020-09-30 EP disclosed
US-20200297700-A1 BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF TOBIRA THERAPEUTICS INC (US) 2020-09-24 US disclosed
EP-2459220-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2020-09-09 EP disclosed
US-10761087-B2 Choroidal neovascularization suppressor or drusen formation suppressor, and method for assessing or screening for same LINK GENOMICS, INC. (JP) 2020-09-01 US disclosed
EP-3391883-B1 CHOROIDAL NEOVASCULARIZATION SUPPRESSOR OR DRUSEN FORMATION SUPPRESSOR, AND METHOD FOR ASSESSING OR SCREENING FOR SAME LINK GENOMICS INC (JP) 2020-08-19 EP disclosed
US-10745397-B2 1-Substituted 1,2,3,4-tetrahydro-1,7-naphthyridin-8-amine derivatives and their use as EP4 receptor antagonists TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-08-18 US disclosed
US-10738004-B2 Cyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-08-11 US disclosed
CN-111440253-A Cubic cyclodextrin framework-RGD composition and preparation method thereof 中国科学院上海药物研究所 2020-07-24 CN disclosed
WO-2020147754-A1 CUBIC CYCLODEXTRIN FRAMEWORK-RGD COMPOSITION AND PREPARATION METHOD THEREFOR 中国科学院上海药物研究所 2020-07-23 WO disclosed
US-10660899-B2 Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate THE SCRIPPS RESEARCH INSTITUTE (US) 2020-05-26 US disclosed
US-10653795-B2 2020-05-19 US disclosed
EP-2741782-B1 PROTEIN CARRIER-LINKED PRODRUGS ASCENDIS PHARMA AS (DK) 2020-05-06 EP disclosed
EP-3643306-A2 CARRIER-LINKED PRODRUGS HAVING REVERSIBLE CARBOXYLIC ESTER LINKAGES Ascendis Pharma A/S (DK) 2020-04-29 EP disclosed
EP-3643716-A1 HETEROARYL COMPOUND HAVING PHARMACEUTICAL ACTIVITY Shanghai Dude Medical Technology Co., Ltd (CN) 2020-04-29 EP disclosed
US-20200123156-A1 HETEROARYL COMPOUND HAVING DRUG ACTIVITY SHANGHAI DUDE MEDICAL TECHNOLOGY CO., LTD 2020-04-23 US disclosed
US-10618257-B2 Light-shielding sheet and container FUJIMORI KOGYO CO., LTD. (JP) 2020-04-14 US disclosed
EP-3325475-B1 OXADIAZOLE DERIVATIVES USEFUL AS HDAC INHIBITORS TAKEDA PHARMACEUTICALS CO (JP) 2020-03-18 EP disclosed
US-20200048256-A1 PURINONE DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2020-02-13 US disclosed
EP-3112368-B1 PURINONE DERIVATIVE AS BTK KINASE INHIBITOR ONO PHARMACEUTICAL CO (JP) 2020-02-12 EP disclosed
WO-2020027225-A1 HETEROCYCLIC COMPOUND ファイメクス株式会社 2020-02-06 WO disclosed
EP-3066094-B1 PYRAZOLE FOR THE TREATMENT AUTOIMMUNE DISORDERS TAKEDA PHARMACEUTICALS CO (JP) 2020-01-08 EP disclosed
EP-3325490-B1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICALS CO (JP) 2019-12-18 EP disclosed
CN-107835800-B Cyclic compound 武田药品工业株式会社 2019-11-26 CN disclosed
EP-3569249-A1 MEDICINAL COMPOSITION FOR TREATING INTRACTABLE HEART DISEASE Osaka University (JP) 2019-11-20 EP disclosed
US-20190343841-A1 Medicinal Composition for Treating Intractable Heart Disease OSAKA UNIVERSITY (JP) 2019-11-14 US disclosed
US-10472376-B2 Amide compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-11-12 US disclosed
US-20190321299-A1 ORAL DRUG DOSAGE FORM COMPRISING VARIOUS RELEASE PROFILES Triastek, Inc. (CN) 2019-10-24 US disclosed
US-20190315748-A1 PURINONE DERIVATIVE HYDROCHLORIDE ONO PHARMACEUTICAL CO., LTD. (JP) 2019-10-17 US disclosed
WO-2019189876-A1 (CARBOXYLIC ACID-TYPE COMPOUND)-POLYMER CONJUGATE HAVING BIOLOGICAL ACTIVITY, AND METHOD FOR PRODUCING SAME 生化学工業株式会社 2019-10-03 WO disclosed
CN-110290781-A The dosage form of stomach and intestine privileged site control release 南京三迭纪医药科技有限公司 2019-09-27 CN disclosed
WO-2019177117-A1 DRUG FOR TREATING COUGH 日本ケミファ株式会社 2019-09-19 WO disclosed
US-10406146-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-09-10 US disclosed
EP-3115057-B1 USE OF IMMUNESUPPRESSANT RECEPTOR ONO PHARMACEUTICAL CO (JP) 2019-09-04 EP disclosed
US-20190256531-A1 SUBSTITUTED DIHYDROPYRROLOPYRAZOLE DERIVATIVE UBE INDUSTRIES, LTD. (JP) 2019-08-22 US disclosed
US-10370377-B2 Purinone derivative hydrochloride ONO PHARMACEUTICAL CO., LTD. (JP) 2019-08-06 US disclosed
US-20190233370-A1 CYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-08-01 US disclosed
US-10363220-B2 Compartmented pharmaceutical dosage forms Triastek, Inc. (CN) 2019-07-30 US disclosed
US-10357484-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-07-23 US disclosed
EP-3511320-A1 CYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2019-07-17 EP disclosed
US-20190192440-A1 ORAL DRUG DOSAGE FORM COMPRISING DRUG IN THE FORM OF NANOPARTICLES Triastek, Inc. (CN) 2019-06-27 US disclosed
CN-109923101-A Cyclic compound 武田药品工业株式会社 2019-06-21 CN disclosed
US-10323095-B2 Antibody-fynomer conjugates MITSUBISHI TANABE PHARMA CORPORATION (JP) 2019-06-18 US disclosed
US-20190169192-A1 PURINONE DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2019-06-06 US disclosed
US-10308643-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-06-04 US disclosed
US-20190133924-A1 Alcohol-Resistant Formulations CIMA LABS INC (US) 2019-05-09 US disclosed
EP-2913047-B1 PULMONARY DISEASE-SPECIFIC THERAPEUTIC AGENT CARDIO INCORPORATED (JP) 2019-05-08 EP disclosed
CN-107847398-B Control the pharmaceutical dosage form of release 南京三迭纪医药科技有限公司 2019-05-07 CN disclosed
US-10273252-B2 Substituted dihydropyrrolopyrazole derivative UBE INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10258575-B2 Oral drug dosage forms having desired drug release profiles and uses thereof Triastek, Inc. (CN) 2019-04-16 US disclosed
US-10233185-B2 Purinone derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2019-03-19 US disclosed
EP-3452003-A1 CONTROLLED RELEASE DOSAGE FORM Triastek, Inc. (CN) 2019-03-13 EP disclosed
CN-109431965-A Pharmaceutical formulation and its use 南京三迭纪医药科技有限公司 2019-03-08 CN disclosed
CN-109432039-A Pharmaceutical formulation and its use 南京三迭纪医药科技有限公司 2019-03-08 CN disclosed
US-20190038604-A1 BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF TOBIRA THERAPEUTICS, INC. (US) 2019-02-07 US disclosed
US-20190030010-A1 PHENYL DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2019-01-31 US disclosed
US-20190008836-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-01-10 US disclosed
CN-104940943-B By spraying with the mucocutaneous attached type preparation of gel-type and the drug delivery system for using it 东兴药品工业株式会社 2019-01-04 CN disclosed
CN-109111446-A A kind of heteroaryl compound with pharmaceutical activity 上海度德医药科技有限公司 2019-01-01 CN disclosed
WO-2018137686-A9 DOSAGE FORMS OF CONTROLLED RELEASE AT SPECIFIC GASTROINTESTINAL SITES Triastek, Inc. (CN) 2018-12-27 WO disclosed
US-20180364216-A1 CHOROIDAL NEOVASCULARIZATION SUPPRESSOR OR DRUSEN FORMATION SUPPRESSOR, AND METHOD FOR ASSESSING OR SCREENING FOR SAME ROHTO PHARMACEUTICAL CO., LTD. (JP) 2018-12-20 US disclosed
US-20180360974-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2018-12-20 US disclosed
US-10143626-B2 Controlled release dosage form Triastek, Inc. (CN) 2018-12-04 US disclosed
CN-108883096-A Choroidal neovascularization inhibitor or drusen inhibitor and evaluation or screening method thereof 林科杰诺米克斯股份有限公司 2018-11-23 CN disclosed
US-20180335433-A1 COMPOSITIONS TARGETING PKC-THETA AND USES AND METHODS OF TREATING PKC-THETA PATHOLOGIES, ADVERSE IMMUNE RESPONSES AND DISEASES LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2018-11-22 US disclosed
CN-105481771-B A kind of preparation process of ozagrel intermediate (E) -4- (imidazolyl methyl) methyl cinnamate 济南诚汇双达化工有限公司 2018-11-09 CN disclosed
US-20180319812-A1 HETEROCYCLIC COMPOUND ACTION MEDICAL TECHNOLOGIES, LLC 2018-11-08 US disclosed
WO-2018204764-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION (US) 2018-11-08 WO disclosed
US-10117861-B2 Phenyl derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2018-11-06 US disclosed
CN-108721242-A Pharmaceutical formulation and its use 南京三迭纪医药科技有限公司 2018-11-02 CN disclosed
US-20180311167-A1 DOSAGE FORMS AND USE THEREOF Triastek, Inc. (CN) 2018-11-01 US disclosed
CN-104098514-B Ozagrel newly crystalline substance II types substance and preparation method and its pharmaceutical composition and purposes 中国医学科学院药物研究所 2018-10-30 CN disclosed
EP-3391883-A1 CHOROIDAL NEOVASCULARIZATION SUPPRESSOR OR DRUSEN FORMATION SUPPRESSOR, AND METHOD FOR ASSESSING OR SCREENING FOR SAME Link Genomics, Inc. (JP) 2018-10-24 EP disclosed
CN-108653221-A Pharmaceutical formulation and its use 南京三迭纪医药科技有限公司 2018-10-16 CN disclosed
US-10093629-B2 Heterocyclic compounds and their use as retinoid-related orphan receptor (ROR) gamma-T inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-10-09 US disclosed
US-10081624-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-09-25 US disclosed
US-20180263967-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-09-20 US disclosed
WO-2018163131-A1 RELEASABLE CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2018-09-13 WO disclosed
US-20180244675-A1 PURINONE DERIVATIVE HYDROCHLORIDE ONO PHARMACEUTICAL CO., LTD. (JP) 2018-08-30 US disclosed
EP-3150577-B1 PHENYL DERIVATIVE ONO PHARMACEUTICAL CO (JP) 2018-08-29 EP disclosed
US-10053468-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-08-21 US disclosed
CN-108395405-A A kind of ozagrel intermediate production technology 中卫市创科知识产权投资有限公司 2018-08-14 CN disclosed
CN-108395405-A A kind of ozagrel intermediate production technology 中卫市创科知识产权投资有限公司 2018-08-14 CN disclosed
US-20180222896-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-08-09 US disclosed
US-20180215754-A1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-08-02 US disclosed
WO-2018137686-A1 DOSAGE FORMS OF CONTROLLED RELEASE AT SPECIFIC GASTROINTESTINAL SITES Triastek, Inc. (CN) 2018-08-02 WO disclosed
CN-105189454-B Phenyl derivatives 小野药品工业株式会社 2018-07-13 CN disclosed
EP-2465539-B1 DISINTEGRATING PARTICLE COMPOSITION AND ORALLY RAPIDLY DISINTEGRATING TABLET FUJI CHEM IND CO LTD (JP) 2018-07-11 EP disclosed
US-20180186818-A1 SUBSTITUTED DIHYDROPYRROLOPYRAZOLE DERIVATIVE UBE INDUSTRIES, LTD. (JP) 2018-07-05 US disclosed
EP-3342772-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2018-07-04 EP disclosed
US-10004701-B2 Methods and compositions for treating infection UNIVERSITY OF ROCHESTER (US) 2018-06-26 US disclosed
US-20180170933-A1 PURINONE DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2018-06-21 US disclosed
US-10000488-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-06-19 US disclosed
EP-3327019-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2018-05-30 EP disclosed
EP-3325475-A1 OXADIAZOLE DERIVATIVES USEFUL AS HDAC INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2018-05-30 EP disclosed
EP-3325490-A1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS Takeda Pharmaceutical Company Limited (JP) 2018-05-30 EP disclosed
US-9981966-B2 Purinone derivative hydrochloride ONO PHARMACEUTICAL CO., LTD. (JP) 2018-05-29 US disclosed
US-20180116911-A1 CONTROLLED RELEASE DOSAGE FORM Triastek, Inc. (CN) 2018-05-03 US disclosed
US-20180118797-A1 USE OF IMMUNESUPPRESSANT RECEPTOR ONO PHARMACEUTICAL CO., LTD. (JP) 2018-05-03 US disclosed
US-20180118708-A1 CYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-05-03 US disclosed
US-20180111991-A1 MODULATORS OF ACTIVIN AND METHODS FOR MODULATING IMMUNE RESPONSES AND T FOLLICULAR HELPER CELLS LA JOLLA INST ALLERGY & IMMUNOLOGY (US) 2018-04-26 US disclosed
EP-2980072-B1 PHENYL DERIVATIVE ONO PHARMACEUTICAL CO (JP) 2018-04-25 EP disclosed
EP-3309163-A1 SUBSTITUTED DIHYDROPYRROLOPYRAZOLE DERIVATIVE UBE Industries, Ltd. (JP) 2018-04-18 EP disclosed
US-20180099000-A1 Method for the Prophylaxis or Treatment of Systemic Lupus Erythematosus and/or Lupus Nephritis MILLENNIUM PHARM INC (US) 2018-04-12 US disclosed
EP-3302442-A1 DOSAGE FORMS AND USE THEREOF Triastek, Inc. (CN) 2018-04-11 EP disclosed
CN-105228923-B Anti-dazzling screen and container 藤森工业株式会社 2018-03-30 CN disclosed
US-9926322-B2 Purinone derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2018-03-27 US disclosed
CN-107847398-A The pharmaceutical dosage form of control release 南京三迭纪医药科技有限公司 2018-03-27 CN disclosed
EP-3296296-A1 CYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2018-03-21 EP disclosed
EP-3294706-A1 CYCLIC COMPOUNDS Takeda Pharmaceutical Company Limited (JP) 2018-03-21 EP disclosed
CN-107735401-A Substituted Dihydropyrrolopyrazole Derivatives 宇部兴产株式会社 2018-02-23 CN disclosed
US-9896453-B2 Purinone derivative hydrochloride ONO PHARMACEUTICAL CO., LTD. (JP) 2018-02-20 US disclosed
WO-2018030550-A1 HETEROCYCLIC COMPOUNDS WITH AN ROR(GAMMA)T MODULATING ACTIVITY TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-02-15 WO disclosed
US-20180042908-A1 PHENYL DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2018-02-15 US disclosed
US-9890145-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-02-13 US disclosed
US-9879013-B2 Purinone derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2018-01-30 US disclosed
CN-206934352-U Pharmaceutical formulation 南京三迭纪医药科技有限公司 2018-01-30 CN disclosed
US-9873744-B1 Methods of treating OX40 mediated recall immune responses using OX40L antibodies and agents useful for identifying same LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2018-01-23 US disclosed
US-9856299-B2 Use of immunesuppressant receptor ONO PHARMACEUTICAL CO., LTD. (JP) 2018-01-02 US disclosed
EP-2980089-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2017-12-20 EP disclosed
US-9834820-B2 Methods for the treatment and diagnosis of bone mineral density related diseases INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2017-12-05 US disclosed
US-9834520-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-12-05 US disclosed
US-9828357-B2 Cyclic compounds TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-11-28 US disclosed
US-9820980-B2 Phenyl derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2017-11-21 US disclosed
WO-2017193099-A1 CONTROLLED RELEASE DOSAGE FORM LI XIAOLING (US) 2017-11-09 WO disclosed
US-20170313705-A1 PURINONE DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2017-11-02 US disclosed
US-20170313706-A1 PURINONE DERIVATIVE HYDROCHLORIDE ONO PHARMACEUTICAL CO., LTD. (JP) 2017-11-02 US disclosed
EP-2227560-B1 METHODS FOR THE TREATMENT AND DIAGNOSIS OF BONE MINERAL DENSITY RELATED DISEASES INSERM - INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE (FR) 2017-10-18 EP disclosed
US-9770419-B2 Methods and compositions of camel derived products MOUSA SHAKER A (US) 2017-09-26 US disclosed
US-20170253591-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-09-07 US disclosed
EP-2738170-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2017-08-30 EP disclosed
US-9732082-B2 2017-08-15 US disclosed
EP-2014305-B1 SPRAYABLE GEL-TYPE SKIN/MUCOSA-ADHESIVE PREPARATION AND ADMINISTRATION SYSTEM USING THE PREPARATION TOKO YAKUHIN KOGYO KK (JP) 2017-08-09 EP disclosed
EP-2759533-B1 CONDENSED HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2017-08-02 EP disclosed
EP-3192791-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2017-07-19 EP disclosed
EP-3187497-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2017-07-05 EP disclosed
US-20170174682-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-06-22 US disclosed
EP-2762466-B1 PHENYL DERIVATIVE ONO PHARMACEUTICAL CO (JP) 2017-06-21 EP disclosed
US-9676719-B2 Phenyl derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2017-06-13 US disclosed
WO-2017095428-A1 MODULATORS OF ACTIVIN AND METHODS FOR MODULATING IMMUNE RESPONSES AND T FOLLICULAR HELPER CELLS LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2017-06-08 WO disclosed
US-20170144973-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS RETINOID-RELATED ORPHAN RECEPTOR (ROR) GAMMA-T INHIBITORS Takenda Pharmaceutical Company Limited (JP) 2017-05-25 US disclosed
US-20170136029-A1 DIRECTED DIFFERENTIATION OF OLIGODENDROCYTE PRECURSOR CELLS TO A MYELINATING CELL FATE IRM LLC (BM) 2017-05-18 US disclosed
US-9650343-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-05-16 US disclosed
EP-3164388-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS RETINOID-RELATED ORPHAN RECEPTOR (ROR) GAMMA-T INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2017-05-10 EP disclosed
US-9643967-B2 Pyrrolo[3,2-c]pyridine derivatives as TLR inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-05-09 US disclosed
US-9637483-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-05-02 US disclosed
CN-206120770-U Medicine formulation 南京三迭纪医药科技有限公司 2017-04-26 CN disclosed
CN-206120771-U Medicine formulation 南京三迭纪医药科技有限公司 2017-04-26 CN disclosed
US-9630924-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-04-25 US disclosed
US-20170105969-A1 CENICRIVIROC FOR THE TREATMENT OF HIV-2 INFECTION TOBIRA THERAPEUTICS, INC. 2017-04-20 US disclosed
US-20170107240-A1 AMIDE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-04-20 US disclosed
US-20170096422-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-04-06 US disclosed
EP-3148538-A1 CENICRIVIROC FOR THE TREATMENT OF HIV-2 INFECTION Tobira Therapeutics, Inc. (US) 2017-04-05 EP disclosed
EP-3150577-A1 PHENYL DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2017-04-05 EP disclosed
US-9611244-B2 Cyclic compounds TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-04-04 US disclosed
US-20170081412-A1 ANTIBODY-FYNOMER CONJUGATES MITSUBISHI TANABE PHARMA CORPORATION (JP) 2017-03-23 US disclosed
US-9592288-B2 Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate THE SCRIPPS RESEARCH INSTITUTE (US) 2017-03-14 US disclosed
US-20170066737-A1 CYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-03-09 US disclosed
US-20170065540-A1 METHODS AND COMPOSITIONS FOR TREATING INFECTION UNIVERSITY OF ROCHESTER (US) 2017-03-09 US disclosed
WO-2017038909-A1 HETEROCYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-03-09 WO disclosed
US-20170050974-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-02-23 US disclosed
US-9573903-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-02-21 US disclosed
CN-106380448-A Preparation method of ozagrel 扬子江药业集团江苏海慈生物药业有限公司 2017-02-08 CN disclosed
EP-3124487-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2017-02-01 EP disclosed
WO-2017014323-A1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-01-26 WO disclosed
WO-2017014321-A1 OXADIAZOLE DERIVATIVES USEFUL AS HDAC INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-01-26 WO disclosed
EP-3119885-A1 ANTIBODY-FYNOMER CONJUGATES Mitsubishi Tanabe Pharma Corporation (JP) 2017-01-25 EP disclosed
CN-104507940-B Heterocyclic compounds 武田药品工业株式会社 2017-01-25 CN disclosed
US-20170015655-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-01-19 US disclosed
US-20170008885-A1 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AS TLR INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-01-12 US disclosed
EP-3115057-A1 USE OF IMMUNESUPPRESSANT RECEPTOR ONO Pharmaceutical Co., Ltd. (JP) 2017-01-11 EP disclosed
EP-3112368-A1 PURINONE DERIVATIVE AS BTK KINASE INHIBITOR ONO PHARMACEUTICAL CO., LTD. (JP) 2017-01-04 EP disclosed
US-9533966-B2 Cyclic compounds TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-01-03 US disclosed
CN-106236715-A Pharmaceutical dosage forms and uses thereof 南京三迭纪医药科技有限公司 2016-12-21 CN disclosed
WO-2016199943-A1 HETEROCYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-12-15 WO disclosed
US-20160354315-A1 DOSAGE FORMS AND USE THEREOF Triastek, Inc. (CN) 2016-12-08 US disclosed
WO-2016192680-A1 DOSAGE FORMS AND USE THEREOF Triastek, Inc. (CN) 2016-12-08 WO disclosed
CN-106211782-A Antibody fynomer conjugate 田边三菱制药株式会社 2016-12-07 CN disclosed
WO-2016182036-A1 CYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-11-17 WO disclosed
US-20160326133-A1 CYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-11-10 US disclosed
US-20160326102-A1 CYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-11-10 US disclosed
US-20160311811-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-10-27 US disclosed
EP-3080124-A1 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AS TLR INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2016-10-19 EP disclosed
US-9464105-B2 Hydroxylated KRN7000 analogue and use thereof RIKEN (JP) 2016-10-11 US disclosed
EP-2465540-B1 DISINTEGRATING PARTICLE COMPOSITION AND ORALLY RAPIDLY DISINTEGRATING TABLET FUJI CHEM IND CO LTD (JP) 2016-10-05 EP disclosed
US-9446055-B2 Disintegrating particle composition and orally rapidly disintegrating tablet FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2016-09-20 US disclosed
US-20160264576-A1 PURINONE DERIVATIVE HYDROCHLORIDE ONO PHARMACEUTICAL CO., LTD. (JP) 2016-09-15 US disclosed
EP-3066094-A1 PYRAZOLE FOR THE TREATMENT AUTOIMMUNE DISORDERS Takeda Pharmaceutical Company Limited (JP) 2016-09-14 EP disclosed
EP-2786996-B1 PURINONE DERIVATIVE HYDROCHLORIDE ONO PHARMACEUTICAL CO (JP) 2016-09-14 EP disclosed
US-20160251352-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2016-09-01 US disclosed
US-20160250238-A1 Method for the Prophylaxis or Treatment of Systemic Lupus Erythematosus and/or Lupus Nephritis MILLENNIUM PHARMACEUTICALS, INC. (US) 2016-09-01 US disclosed
CN-105481772-B A kind of sodium ozagrel crystal-form compound 郭琨 2016-08-31 CN disclosed
CN-103958465-B Phenyl derivatives 小野药品工业株式会社 2016-08-31 CN disclosed
US-20160229814-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-08-11 US disclosed
EP-3052105-A1 METHOD FOR THE PROPHYLAXIS OR TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS AND/OR LUPUS NEPHRITIS Millennium Pharmaceuticals, Inc. (US) 2016-08-10 EP disclosed
WO-2016123541-A2 CENICRIVIROC FOR THE TREATMENT OF ENCEPHALITIS INFECTION TOBIRA THERAPEUTICS, INC. (US) 2016-08-04 WO disclosed
US-20160213660-A1 PHENYL DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2016-07-28 US disclosed
EP-2578585-B1 PURINONE DERIVATIVE AS BTK KINASE INHIBITOR ONO PHARMACEUTICAL CO (JP) 2016-07-20 EP disclosed
US-9393221-B2 Methods and compounds for reducing intracellular lipid storage THE GENERAL HOSPITAL CORPORATION (US) 2016-07-19 US disclosed
US-20160176872-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL (JP) 2016-06-23 US disclosed
US-20160176822-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL (JP) 2016-06-23 US disclosed
US-20160176873-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL (JP) 2016-06-23 US disclosed
CN-105705149-A Method for the prophylaxis or treatment of systemic lupus erythematosus and/or lupus nephritis 米伦纽姆医药公司 2016-06-22 CN disclosed
US-9371320-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-21 US disclosed
US-9371325-B2 Purinone derivative hydrochloride ONO PHARMACEUTICAL CO., LTD. (JP) 2016-06-21 US disclosed
US-20160166687-A1 DIRECTED DIFFERENTIATION OF OLIGODENDROCYTE PRECURSOR CELLS TO A MYELINATING CELL FATE THE SCRIPPS RESEARCH INSTITUTE 2016-06-16 US disclosed
US-9365520-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-14 US disclosed
US-20160159773-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-09 US disclosed
WO-2016090035-A2 MODULATORS OF ACTIVIN AND METHODS FOR MODULATING IMMUNE RESPONSES AND T FOLLICULAR HELPER CELLS LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2016-06-09 WO disclosed
WO-2016088903-A1 HETEROCYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-09 WO disclosed
EP-3029031-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-06-08 EP disclosed
US-9340499-B2 Phenyl derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2016-05-17 US disclosed
EP-3018126-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-05-11 EP disclosed
EP-3018123-A1 AMIDE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-05-11 EP disclosed
US-9321757-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-04-26 US disclosed
CN-105481772-A Ozagrel sodium crystal type compound GUO KUN 2016-04-13 CN disclosed
CN-105481771-A Preparation process of ozagrel intermediate methyl (E)-4-(imidazolylmethyl) cinnamate JINAN CHENGHUI SHUANGDA CHEMICAL CO LTD 2016-04-13 CN disclosed
US-20160089864-A1 Light-Shielding Sheet And Container FUJIMORI KOGYO CO., LTD. (JP) 2016-03-31 US disclosed
EP-3000750-A1 LIGHT-SHIELDING SHEET AND CONTAINER Fujimori Kogyo Co., Ltd. (JP) 2016-03-30 EP disclosed
US-20160082123-A1 Hydrogel-Linked Prodrugs Releasing Tagged Drugs ASCENDIS PHARMA A/S (DK) 2016-03-24 US disclosed
EP-2583964-B1 NEW CRYSTALLINE FORMS OF 4,4'-[4-FLUORO-7-({4-[4-(3-FLUORO-2-METHYLPHENYL)BUTOXY]PHENYL}ETHYNYL)-2-METHYL-1H-INDOLE-1,3-DIYL]DIBUTANOIC ACID ONO PHARMACEUTICAL CO (JP) 2016-03-23 EP disclosed
US-20160075753-A1 MODULATION OF REGULATORY T CELL FUNCTION VIA PROTEIN KINASE C-eta LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY 2016-03-17 US disclosed
EP-2992086-A2 MODULATION OF REGULATORY T CELL FUNCTION VIA PROTEIN KINASE C- La Jolla Institute for Allergy and Immunology (US) 2016-03-09 EP disclosed
EP-2988783-A1 HYDROGEL-LINKED PRODRUGS RELEASING MODIFIED DRUGS Ascendis Pharma A/S (DK) 2016-03-02 EP disclosed
US-20160039757-A1 PHENYL DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2016-02-11 US disclosed
US-20160039811-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-02-11 US disclosed
WO-2016021742-A1 HETEROCYCLIC COMPOUNDS AS EP4 RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-02-11 WO disclosed
EP-2980089-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-02-03 EP disclosed
EP-2980072-A1 PHENYL DERIVATIVE ONO Pharmaceutical Co., Ltd. (JP) 2016-02-03 EP disclosed
EP-2975031-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2016-01-20 EP disclosed
US-20160008326-A1 BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-01-14 US disclosed
US-20160002169-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-01-07 US disclosed
WO-2016002968-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS RETINOID-RELATED ORPHAN RECEPTOR (ROR) GAMMA-T INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-01-07 WO disclosed
CN-105228923-A Shade and container FUJIMORI KOGYO CO LTD 2016-01-06 CN disclosed
CN-103958513-B Hypoxanthine derivant hydrochloric acid salt ONO PHARMACEUTICAL CO.,LTD. (JP) 2015-12-23 CN disclosed
CN-105189454-A Phenyl derivative ONO PHARMACEUTICAL CO 2015-12-23 CN disclosed
WO-2015187663-A1 CENICRIVIROC FOR THE TREATMENT OF HIV-2 INFECTION TOBIRA THERAPEUTICS, INC. (US) 2015-12-10 WO disclosed
US-9199997-B2 Purinone derivative hydrochloride ONO PHARMACEUTICAL CO., LTD. (JP) 2015-12-01 US disclosed
US-9187453-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-11-17 US disclosed
US-9156837-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-10-13 US disclosed
US-20150274731-A1 PURINONE DERIVATIVE HYDROCHLORIDE ONO PHARMACEUTICAL CO (JP) 2015-10-01 US disclosed
US-20150272874-A1 PULMONARY DISEASE-SPECIFIC THERAPEUTIC AGENT CARDIO INCORPORATED (JP) 2015-10-01 US disclosed
CN-104940943-A Sprayable gel-type skin/mucosa-adhesive preparation and administration system using the preparation TOKO YAKUHIN KOGYO KK 2015-09-30 CN disclosed
WO-2015141862-A1 ANTIBODY-FYNOMER CONJUGATES MITSUBISHI TANABE PHARMA CORPORATION (JP) 2015-09-24 WO disclosed
EP-2913047-A1 PULMONARY DISEASE-SPECIFIC THERAPEUTIC AGENT Cardio, Inc. (JP) 2015-09-02 EP disclosed
US-9120776-B2 Condensed heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-09-01 US disclosed
US-20150238473-A1 METHODS AND COMPOSITIONS FOR TREATING INFECTION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-08-27 US disclosed
US-20150218199-A1 HYDROXYLATED KRN7000 ANALOGUE AND USE THEREOF RIKEN (JP) 2015-08-06 US disclosed
US-9085578-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-07-21 US disclosed
US-9072734-B2 Quaternary ammonium salt compounds TEIJIN PHARMA LIMITED (JP) 2015-07-07 US disclosed
EP-2177513-B1 PHENYLACETIC ACID COMPOUND ONO PHARMACEUTICAL CO (JP) 2015-07-01 EP disclosed
WO-2015088045-A1 PYRROLO[3,2-C]PYRIDINE DERIVATIVES AS TLR INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-06-18 WO disclosed
EP-2881400-A1 HYDROXYLATED KRN7000 ANALOGUE AND USE THEREOF Riken (JP) 2015-06-10 EP disclosed
US-20150141406-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-05-21 US disclosed
WO-2015068856-A1 PYRAZOLE FOR THE TREATMENT AUTOIMMUNE DISORDERS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-05-14 WO disclosed
US-20150133451-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-05-14 US disclosed
US-20150126486-A1 PHENYL DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2015-05-07 US disclosed
CN-102459231-B Quaternary ammonium salt compound TEIJIN PHARMA LTD 2015-04-22 CN disclosed
US-20150104437-A1 METHODS FOR THE TREATMENT AND DIAGNOSIS OF BONE MINERAL DENSITY RELATED DISEASES Universite De Paris (FR) 2015-04-16 US disclosed
WO-2015051067-A1 METHOD FOR THE PROPHYLAXIS OR TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS AND/OR LUPUS NEPHRITIS MILLENNIUM PHARMACEUTICALS, INC. (US) 2015-04-09 WO disclosed
EP-2857400-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2015-04-08 EP disclosed
CN-104507940-A Heterocyclic compounds TAKEDA PHARMACEUTICAL 2015-04-08 CN disclosed
US-20150093383-A1 USE OF IMMUNESUPPRESSANT RECEPTOR ONO PHARMACEUTICAL CO., LTD. (JP) 2015-04-02 US disclosed
US-20150094296-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-04-02 US disclosed
US-20150094299-A1 PURINONE DERIVATIVE ONO PHARMACEUTICAL CO (JP) 2015-04-02 US disclosed
CN-102918040-B Purinone derivative ONO PHARMACEUTICAL CO 2015-03-18 CN disclosed
US-8975409-B2 Phenyl derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2015-03-10 US disclosed
EP-2308562-B1 Azetidine ring compounds and drugs comprising the same ONO PHARMACEUTICAL CO (JP) 2015-02-25 EP disclosed
US-8962623-B2 Aminopyrazine compounds LOCUS PHARMACEUTICALS, INC. (US) 2015-02-24 US disclosed
US-8956615-B1 Methods of treating OX40 mediated recall immune responses using OX40L antibodies and agents useful for identifying same LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2015-02-17 US disclosed
US-20150045349-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED 2015-02-12 US disclosed
EP-2832734-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2015-02-04 EP disclosed
US-8945557-B2 Use of immunesuppressant receptor ONO PHARMACEUTICAL CO., LTD. (JP) 2015-02-03 US disclosed
US-8940725-B2 Purinone derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2015-01-27 US disclosed
EP-2298352-B1 PERCUTANEOUS ABSORPTION ENHANCER AND TRANSDERMAL PREPARATION USING THE SAME TOA EIYO LTD (JP) 2015-01-14 EP disclosed
CN-101212986-B Stable emulsified composition TAKEDA PHARMACEUTICAL 2015-01-14 CN disclosed
EP-2818473-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2014-12-31 EP disclosed
EP-2424368-B1 PYRROLOTRIAZINE COMPOUNDS LOCUS PHARMACEUTICALS INC (US) 2014-12-31 EP disclosed
US-20140357630-A1 Phenylacetic Acid Compound ONO PHARMACEUTICAL CO., LTD. (JP) 2014-12-04 US disclosed
US-8900602-B2 Disintegrating particle composition and orally rapidly disintegrating tablet FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2014-12-02 US disclosed
US-20140330015-A1 PURINONE DERIVATIVE HYDROCHLORIDE ONO PHARMACEUTICAL CO., LTD (JP) 2014-11-06 US disclosed
WO-2014179491-A2 MODULATION OF REGULATORY T CELL FUNCTION VIA PROTEIN KINASE C-η LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2014-11-06 WO disclosed
CN-102633723-B Preparation method of ozagrel TIBET YIMING XIYA BIOLOG MEDICAL TECHNOLOGY CO LTD 2014-11-05 CN disclosed
US-20140323402-A1 Protein Carrier-Linked Prodrugs Ascendis Phama A/S (DK) 2014-10-30 US disclosed
WO-2014173759-A1 HYDROGEL-LINKED PRODRUGS RELEASING MODIFIED DRUGS ASCENDIS PHARMA A/S (DK) 2014-10-30 WO disclosed
CN-104098514-A Ozagrel new crystal II material, preparation method, pharmaceutical composition and use INST MATERIA MEDICA CAMS 2014-10-15 CN disclosed
EP-2786996-A1 PURINONE DERIVATIVE HYDROCHLORIDE ONO Pharmaceutical Co., Ltd. (JP) 2014-10-08 EP disclosed
US-20140296257-A1 High-Loading Water-Soluable Carrier-Linked Prodrugs ASCENDIS PHARMA A/S (DK) 2014-10-02 US disclosed
US-8846863-B2 Heat stable protein ingredients UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2014-09-30 US disclosed
EP-2508204-B1 Remedies for diseases caused by vascular contraction or dilation ONO PHARMACEUTICAL CO (JP) 2014-09-24 EP disclosed
US-20140249093-A1 Carrier-Linked Prodrugs Having Reversible Carboxylic Ester Linkages ASCENDIS PHARMA A/S (DK) 2014-09-04 US disclosed
EP-2444401-B1 NOVEL IMIDAZOPYRIDINE COMPOUND ONO PHARMACEUTICAL CO (JP) 2014-09-03 EP disclosed
US-20140243254-A1 Polymeric Hyperbranched Carrier-Linked Prodrugs ASCENDIS PHARMA A/S (DK) 2014-08-28 US disclosed
US-20140235611-A1 PHENYL DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2014-08-21 US disclosed
US-20140234320-A1 MODULATORS OF 4-1BB AND IMMUNE RESPONSES LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2014-08-21 US disclosed
US-8809524-B2 Phenylacetic acid compound ONO PHARMACEUTICAL CO., LTD. (JP) 2014-08-19 US disclosed
US-20140228409-A1 CONDENSED HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-08-14 US disclosed
CN-103080085-B Novel crystalline forms of 4, 4' - [ 4-fluoro-7- ({4- [4- (3-fluoro-2-methylphenyl) butoxy ] phenyl } ethynyl) -2-methyl-1H-indole-1, 3-diyl ] dibutanoic acid ONO PHARMACEUTICAL CO 2014-08-13 CN disclosed
EP-2762466-A1 PHENYL DERIVATIVE ONO Pharmaceutical Co., Ltd. (JP) 2014-08-06 EP disclosed
EP-2759533-A1 CONDENSED HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2014-07-30 EP disclosed
CN-103958465-A Phenyl derivative ONO PHARMACEUTICAL CO 2014-07-30 CN disclosed
CN-103958513-A 6-Hydroxypurine derivative hydrochloride ONO PHARMACEUTICAL CO 2014-07-30 CN disclosed
US-8771724-B2 Percutaneous absorption enhancer and transdermal preparation using the same TOA EIYO LTD. (JP) 2014-07-08 US disclosed
US-8771711-B2 Sprayable gel-type skin/mucosa-adhesive preparation and administration system using the preparation TOKO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 2014-07-08 US disclosed
US-20140186372-A1 COMPOSITIONS TARGETING PKC-THETA AND USES AND METHODS OF TREATING PKC-THETA PATHOLOGIES, ADVERSE IMMUNE RESPONSES AND DISEASES LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2014-07-03 US disclosed
US-20140187529-A1 AMINOPYRAZINE COMPOUNDS LOCUS PHARMACEUTICALS, INC. (US) 2014-07-03 US disclosed
US-8765783-B2 Pharmaceutical composition for treatment of disease due to vascular constriction or vasodilation ONO PHARMACEUTICALS CO., LTD. (JP) 2014-07-01 US disclosed
US-8765754-B2 Pyrrolotriazine compounds LOCUS PHARMACEUTICALS, INC. (US) 2014-07-01 US disclosed
EP-2741782-A1 PROTEIN CARRIER-LINKED PRODRUGS Ascendis Pharma A/S (DK) 2014-06-18 EP disclosed
EP-2741744-A1 CARRIER-LINKED PRODRUGS HAVING REVERSIBLE CARBOXYLIC ESTER LINKAGES Ascendis Pharma A/S (DK) 2014-06-18 EP disclosed
EP-2741778-A1 POLYMERIC HYPERBRANCHED CARRIER-LINKED PRODRUGS Ascendis Pharma A/S (DK) 2014-06-18 EP disclosed
EP-2741779-A1 HIGH-LOADING WATER-SOLUBLE CARRIER-LINKED PRODRUGS Ascendis Pharma A/S (DK) 2014-06-18 EP disclosed
CN-102558061-B Synthetic method of ozagrel BEIJING YMKY PHARMACEUTICAL TECHNOLOGY CO LTD 2014-06-18 CN disclosed
CN-102573913-B Biodegradable polyethylene glycol-based water-insoluble hydrogels ASCENDIS PHARMA AS 2014-06-18 CN disclosed
US-20140163001-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-06-12 US disclosed
EP-2738170-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2014-06-04 EP disclosed
US-8741943-B2 Bicyclic compound, production and use thereof TOBIRA THERAPEUTICS, INC. (US) 2014-06-03 US disclosed
US-8728494-B2 2014-05-20 US disclosed
EP-1806147-B1 USE OF IMMUNESUPPRESSANT RECEPTOR ONO PHARMACEUTICAL CO (JP) 2014-04-30 EP disclosed
EP-2720705-A2 COMPOSITIONS TARGETING PKC-THETA AND USES AND METHODS OF TREATING PKC-THETA PATHOLOGIES, ADVERSE IMMUNE RESPONSES AND DISEASES La Jolla Institute for Allergy and Immunology (US) 2014-04-23 EP disclosed
EP-1522314-B1 REMEDIES FOR DISEASES CAUSED BY VASCULAR CONTRACTION OR DILATION ONO PHARMACEUTICAL CO (JP) 2014-03-05 EP disclosed
CN-103613546-A Chemical synthesizing method of ozagrel UNIV QINGDAO AGRICULTURAL 2014-03-05 CN disclosed
US-20140038949-A1 DIRECTED DIFFERENTIATION OF OLIGODENDROCYTE PRECURSOR CELLS TO A MYELINATING CELL FATE IRM LLC (BM) 2014-02-06 US disclosed
US-20140037722-A1 METHODS AND COMPOSITIONS OF CAMEL DERIVED PRODUCTS MOUSA SHAKER A (US) 2014-02-06 US disclosed
EP-1790637-B1 Derivatives of N-4-piperidyl urea and medicaments containing them as active ingredient ONO PHARMACEUTICAL CO (JP) 2014-01-29 EP disclosed
US-8604207-B2 Nitrogenous heterocyclic derivative and medicine containing the same as an active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2013-12-10 US disclosed
CN-102391186-B Method for preparing ozagrel intermediate (E)-4-(methyl imidazolyl) methyl cinnamate JINAN CHENGHUI SHUANGDA CHEMICAL CO LTD 2013-12-04 CN disclosed
US-8598223-B2 Crystalline forms of 4, 4′-[4-fluoro-7-({4-[4-(3-fluoro-2-methylphenyl) butoxy] phenyl} ethynyl)-2-methyl-1H-indole-1,3-diyl] dibutanoic acid, 4,4′-[2-methyl-7-({4-[4-(pentafluorophenyl) butoxy] phenyl} ethynyl)-1H-indole-1, 3-diyl] dibutanoic acid, and 4,4′-[4-fluoro-2-methyl-7-({4-[4-(2, 3, 4, 6-tetrafluorophenyl) butoxy] phenyl} ethynyl)-1H-indole-1, 3-diyl] dibutanoic acid ONO PHARMACEUTICAL CO., LTD. (JP) 2013-12-03 US disclosed
EP-1889839-B1 Bicyclic compound, production and use as HIV inhibitors TOBIRA THERAPEUTICS INC (US) 2013-11-06 EP disclosed
US-8575167-B2 Spiro compounds having stearoyl-CoA desaturase action TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-11-05 US disclosed
WO-2013162350-A2 CIRCULAR ANTIVIRAL RNA UNIVERSITI PUTRA MALAYSIA (MY) 2013-10-31 WO disclosed
US-8569504-B2 Imidazopyridine compound ONO PHARMACEUTICAL CO., LTD. (JP) 2013-10-29 US disclosed
US-8557803-B2 Purinone derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2013-10-15 US disclosed
US-8551477-B1 Methods of treating OX40 mediated recall immune responses using OX40L antibodies and agents useful for identifying same LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2013-10-08 US disclosed
CN-102065900-B Percutaneous absorption enhancer and transdermal preparation using the same TOA EIYO LTD (JP) 2013-09-25 CN disclosed
EP-1997902-B1 SCREENING METHOD UNIV HIROSHIMA (JP) 2013-09-18 EP disclosed
US-8529879-B2 Epithelium-improving agent Kobayashi, Haruzo (JP) 2013-09-10 US disclosed
US-20130225808-A1 PHENYLACETIC ACID COMPOUND ONO PHARMACEUTICAL CO., LTD. (JP) 2013-08-29 US disclosed
US-20130217880-A1 PURINONE DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2013-08-22 US disclosed
EP-1553075-B1 LPA RECEPTOR ANTAGONISTS ONO PHARMACEUTICAL CO (JP) 2013-08-14 EP disclosed
US-20130202705-A1 ALCOHOL-RESISTANT FORMULATIONS CIMA LABS INC. (US) 2013-08-08 US disclosed
EP-1661892-B1 CONDENSED RING COMPOUND AND USE THEREOF ONO PHARMACEUTICAL CO (JP) 2013-07-24 EP disclosed
US-8476266-B2 Phenylacetic acid compound ONO PHARMACEUTICAL CO., LTD. (JP) 2013-07-02 US disclosed
CN-102626388-B Liposome solid preparation of ozagrel HAINAN YONGTIAN DRUG RES INST CO LTD 2013-05-29 CN disclosed
CN-102626388-B Liposome solid preparation of ozagrel HAINAN YONGTIAN DRUG RES INST CO LTD 2013-05-29 CN disclosed
CN-101921220-B Pharmaceutical compositions for treating diseases with bone mass loss having EP4 agonist as the active ingredient ONO PHARMACEUTICAL CO 2013-05-22 CN disclosed
US-20130108602-A1 METHODS AND USES OF NUR77 AND NUR77 AGONISTS TO MODULATE MACROPHAGES AND MONOCYTES, AND TREAT INFLAMMATION, INFLAMMATORY DISEASE AND CARDIOVASCULAR DISEASE LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2013-05-02 US disclosed
CN-103080085-A 4,4 ' - [ 4-fluoro-7- ({4- [4- (3-fluoro-2-methylphenyl) butoxy ] phenyl } ethynyl) -2-methyl-1H-indole-1, 3-diyl ] dibutanoic acid, 4 ' - [ 2-methyl-7- ({4- [4- (pentafluorophenyl) butoxy ] phenyl } ethynyl) -1H-indole-1, 3-diyl ] dibutanoic acid and 4,4 ' - [ 4-fluoro-2-methyl-7 ONO PHARMACEUTICAL CO 2013-05-01 CN disclosed
EP-2583964-A1 NOVEL CRYSTALLINE FORMS OF 4,4'-[4-FLUORO-7-({4-[4-(3-FLUORO-2-METHYLPHENYL)BUTOXY]PHENYL}ETHYNYL)-2-METHYL-1H-INDOLE-1,3-DIYL]DIBUTANOIC ACID, 4,4'-[2-METHYL-7-({4-[4-(PENTAFLUOROPHENYL)BUTOXY]PHENYL}ETHYNYL)-1H-INDOLE-1,3-DIYL]DIBUTANOIC ACID, AND 4,4'-[4-FLUORO-2-METHYL-7-({4-[4-(2,3,4,6-TETRAFLUOROPHENYL)BUTOXY]PHENYL}ETHYNYL)-1H-INDOLE-1,3-DIYL]DIBUTANOIC ACID ONO Pharmaceutical Co., Ltd. (JP) 2013-04-24 EP disclosed
US-20130095127-A1 METHODS OF INHIBITING INFLAMMATION AND INFLAMMATORY DISEASES USING Gal-3BP (BTBD17B, LGALS3BP, GALECTIN-3 BINDING PROTEIN, MAC-2 BINDING PROTEIN) LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2013-04-18 US disclosed
CN-103044334-A Refining method of ozagrel methyl ester DEZHOU HANHUA CHEM CO LTD 2013-04-17 CN disclosed
CN-103044334-A Refining method of ozagrel methyl ester DEZHOU HANHUA CHEM CO LTD 2013-04-17 CN disclosed
US-20130090482-A1 CRYSTALLINE FORMS OF 4, 4'- [4-FLUORO-7-( ETHYNYL)-2-METHYL-1H-INDOLE-1,3-DIYL] DIBUTANOIC ACID, 4,4'-[2-METHYL-7-( ETHYNYL)-1H-INDOLE-1, 3-DIYL] DIBUTANOIC ACID, AND 4,4'-[4-FLUORO-2-METHYL-7- ( ETHYNYL)-1H-INDOLE-1, 3-DIYL] DIBUTANOIC ACID ONO PHARMACEUTICAL CO., LTD. (JP) 2013-04-11 US disclosed
EP-2578585-A1 PURINONE DERIVATIVE ONO Pharmaceutical Co., Ltd. (JP) 2013-04-10 EP disclosed
US-20130085275-A1 NITROGENOUS HETEROCYCLIC DERIVATIVE AND MEDICINE CONTAINING THE SAME AS AN ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2013-04-04 US disclosed
CN-103006644-A Method for preventing and treating thrombogenesis BEIJING FUKANGREN BIOPHARMACEUTICAL TECHNOLOGY CO LTD 2013-04-03 CN disclosed
CN-103006644-A Method for preventing and treating thrombogenesis BEIJING FUKANGREN BIOPHARMACEUTICAL TECHNOLOGY CO LTD 2013-04-03 CN disclosed
US-8410276-B2 Nitrogenous heterocyclic derivative and medicine containing the same as an active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2013-04-02 US disclosed
US-20130079327-A1 PURINONE DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2013-03-28 US disclosed
EP-2568969-A2 ALCOHOL-RESISTANT FORMULATIONS Cima Labs Inc. (US) 2013-03-20 EP disclosed
US-20130064818-A1 USE OF IMMUNESUPPRESSANT RECEPTOR ONO PHARMACEUTICAL CO., LTD. (JP) 2013-03-14 US disclosed
EP-2566878-A1 METHODS OF INHIBITING INFLAMMATION AND INFLAMMATORY DISEASES USING GAL-3BP (BTBD17B, LGALS3BP, GALECTIN-3 BINDING PROTEIN, MAC-2 BINDING PROTEIN) La Jolla Institute for Allergy and Immunology (US) 2013-03-13 EP disclosed
EP-2565178-A1 LPA Receptor Antagonists ONO PHARMACEUTICAL CO., LTD. (JP) 2013-03-06 EP disclosed
CN-101759628-B Ethynylindole compounds ONO PHARMACEUTICAL CO 2013-02-27 CN disclosed
WO-2013024049-A1 PROTEIN CARRIER-LINKED PRODRUGS ASCENDIS PHARMA A/S (DK) 2013-02-21 WO disclosed
WO-2013024047-A1 HIGH-LOADING WATER-SOLUBLE CARRIER-LINKED PRODRUGS ASCENDIS PHARMA A/S (DK) 2013-02-21 WO disclosed
WO-2013024053-A1 CARRIER-LINKED PRODRUGS HAVING REVERSIBLE CARBOXYLIC ESTER LINKAGES ASCENDIS PHARMA A/S (DK) 2013-02-21 WO disclosed
WO-2013024048-A1 POLYMERIC HYPERBRANCHED CARRIER-LINKED PRODRUGS ASCENDIS PHARMA A/S (DK) 2013-02-21 WO disclosed
CN-102918040-A Purinone derivative ONO PHARMACEUTICAL CO 2013-02-06 CN disclosed
US-20130028887-A1 PHENYLACETIC ACID COMPOUND ONO PHARMACEUTICAL CO., LTD. (JP) 2013-01-31 US disclosed
US-8362058-B2 Bicyclic compound, production and use thereof TOBIRA THERAPEUTICS, INC. (US) 2013-01-29 US disclosed
US-20130023488-A1 METHODS AND COMPOUNDS FOR REDUCING INTRACELLULAR LIPID STORAGE THE GENERAL HOSPITAL CORPORATION (US) 2013-01-24 US disclosed
EP-2546234-A1 Nitrogeneous heterocyclic derivative and medicine containing the same as an active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2013-01-16 EP disclosed
CN-102883713-A Alcohol-resistant formulations CIMA LABS INC 2013-01-16 CN disclosed
EP-2543368-A1 Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties Viamet Pharmaceuticals, Inc. (US) 2013-01-09 EP disclosed
EP-1666473-B1 CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO (JP) 2013-01-02 EP disclosed
WO-2012177788-A1 MODULATORS OF 4-1BB AND IMMUNE RESPONSES LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2012-12-27 WO disclosed
WO-2012174412-A2 COMPOSITIONS TARGETING PKC-THETA AND USES AND METHODS OF TREATING PKC-THETA PATHOLOGIES, ADVERSE IMMUNE RESPONSES AND DISEASES LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2012-12-20 WO disclosed
US-8333969-B2 Use of immunesuppressant receptor ONO PHARMACEUTICAL CO., LTD. (JP) 2012-12-18 US disclosed
US-8329420-B2 Screening method for a substance that binds to an intracellular region of TLR4 HIROSHIMA UNIVERSITY (JP) 2012-12-11 US disclosed
EP-1586564-B1 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICINAL USES THEREOF ONO PHARMACEUTICAL CO (JP) 2012-11-28 EP disclosed
US-8318739-B2 Remedy for corneal diseases TEIKA PHARMACEUTICAL CO., LTD. (JP) 2012-11-27 US disclosed
US-8318952-B2 Substituted indole derivatives for the treatment of respiratory diseases ONO PHARMACEUTICAL CO., LTD. (JP) 2012-11-27 US disclosed
US-8318729-B2 Phenylacetic acid compound ONO PHARMACEUTICAL CO., LTD. (JP) 2012-11-27 US disclosed
EP-1481976-B1 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO (JP) 2012-11-07 EP disclosed
EP-1852420-B1 Indole compounds for treating respiratory disorders ONO PHARMACEUTICAL CO (JP) 2012-10-17 EP disclosed
EP-2508204-A2 Remedies for diseases caused by vascular contraction or dilation ONO PHARMACEUTICAL CO., LTD. (JP) 2012-10-10 EP disclosed
US-20120232054-A1 PYRROLOTRIAZINE COMPOUNDS LOCUS PHARMACEUTICALS, INC. (US) 2012-09-13 US disclosed
US-20120232028-A1 Bicyclic Compound, Production and Use Thereof TOBIRA THERAPEUTICS, INC. (US) 2012-09-13 US disclosed
WO-2012121939-A2 AMINOPYRAZINE COMPOUNDS LOCUS PHARMACEUTICALS, INC. (US) 2012-09-13 WO disclosed
US-20120207728-A1 Epithelium-Improving Agent KOBAYASHI HARUZO (JP) 2012-08-16 US disclosed
US-20120202773-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DISEASES ASSOCIATED WITH DECREASE IN BONE MASS COMPRISING EP4 AGONIST AS ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2012-08-09 US disclosed
CN-102626388-A Liposome solid preparation of ozagrel HAINAN YONGTIAN DRUG RES INST CO LTD 2012-08-08 CN disclosed
EP-2481732-A1 Condensed ring compound and use thereof Ono Pharmaceutical Co., Ltd. (JP) 2012-08-01 EP disclosed
EP-2206698-B1 Ethynylindole compounds ONO PHARMACEUTICAL CO (JP) 2012-07-18 EP disclosed
US-20120165413-A1 DISINTEGRATING PARTICLE COMPOSITION AND ORALLY RAPIDLY DISINTEGRATING TABLET FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2012-06-28 US disclosed
US-8207223-B2 Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising EP4 agonist as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2012-06-26 US disclosed
US-20120156261-A1 DISINTEGRATING PARTICLE COMPOSITION AND ORALLY RAPIDLY DISINTEGRATING TABLET FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2012-06-21 US disclosed
US-20120156219-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2012-06-21 US disclosed
US-20120156259-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels ASCENDIS PHARMA A/S (DK) 2012-06-21 US disclosed
EP-2465538-A2 Use of immunesuppressant receptor ONO PHARMACEUTICAL CO., LTD. (JP) 2012-06-20 EP disclosed
EP-2465539-A1 DISINTEGRATING PARTICLE COMPOSITION AND ORALLY RAPIDLY DISINTEGRATING TABLET FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2012-06-20 EP disclosed
EP-2465540-A1 DISINTEGRATING PARTICLE COMPOSITION AND ORALLY RAPIDLY DISINTEGRATING TABLET FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 2012-06-20 EP disclosed
EP-2459220-A1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS Ascendis Pharma A/S (DK) 2012-06-06 EP disclosed
US-8183273-B2 8-[4-(2-butoxyethoxy)phenyl]-1-isobutyl-N-[4-[[N-methyl-N-(tetrahydropyran-4-yl)amino]methyl]phenyl]-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide; HIV infectious diseases, chronic rheumatoid arthritis, autoimmune disease, allergic diseases, ischemic brain cell disease TOBIRA THERAPEUTICS, INC. (US) 2012-05-22 US disclosed
EP-2444401-A1 NOVEL IMIDAZOPYRIDINE COMPOUND ONO Pharmaceutical Co., Ltd. (JP) 2012-04-25 EP disclosed
US-20120094990-A1 PHENYLACETIC ACID COMPOUND ONO PHARMACEUTICAL CO., LTD. (JP) 2012-04-19 US disclosed
US-20120094944-A1 NOVEL IMIDAZOPYRIDINE COMPOUND ONO PHARMACEUTICAL CO., LTD. (JP) 2012-04-19 US disclosed
US-20120088782-A1 LPA RECEPTOR ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2012-04-12 US disclosed
US-8153625-B2 Nitrogen-containing heterocyclic compounds and medicinal use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2012-04-10 US disclosed
US-20120077856-A1 PHARMACEUTICAL PRODUCT TAKEDA PHARMACEUTICAL COMPANY LIMITED 2012-03-29 US disclosed
US-8143404-B2 N-heterocycle urea compounds such as 5-([(butyl{1-[(2-methyl-6-{4-[(methylsulfonyl)amino]phenoxy)-3-pyridinyl)methyl]-4-piperidinyl}amino)carbonyl]amino)-2,4-difluorobenzamide; chemokine receptor CCR5 antagonists for various inflammatory diseases, autoimmune diseases, infectious diseases ONO PHARMACEUTICAL CO., LTD (JP) 2012-03-27 US disclosed
US-8138335-B2 Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient ONO PHARMACEUTICAL CO., LTD (JP) 2012-03-20 US disclosed
EP-2424368-A1 PYRROLOTRIAZINE COMPOUNDS Locus Pharmaceuticals, Inc. (US) 2012-03-07 EP disclosed
EP-2426121-A1 QUATERNARY AMMONIUM SALT COMPOUND Teijin Pharma Limited (JP) 2012-03-07 EP disclosed
US-8124645-B2 LPA receptor antagonist ONO PHARMACEUTICAL CO., LTD. (JP) 2012-02-28 US disclosed
US-20120046467-A1 QUATERNARY AMMONIUM SALT COMPOUNDS TEIJIN PHARMA LIMITED (JP) 2012-02-23 US disclosed
US-8115014-B2 Ethynylindole compounds ONO Pharmaceuticals, Co., Ltd. (JP) 2012-02-14 US disclosed
EP-1810972-B1 NITROGENOUS HETEROCYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF ONO PHARMACEUTICAL CO (JP) 2012-01-25 EP disclosed
US-8101175-B1 Methods of treating OX40 mediated recall immune responses using OX40L antibodies and agents useful for identifying same LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2012-01-24 US disclosed
EP-2206702-B1 Bicyclic compound, production and use thereof TOBIRA THERAPEUTICS INC (US) 2011-12-28 EP disclosed
EP-1927353-B1 REMEDY FOR CORNEAL DISEASES TEIKA PHARMACEUTICAL CO LTD (JP) 2011-11-23 EP disclosed
CN-102247346-A Novel anti-coagulation medicinal composition BEIJING FUKANGREN BIOPHARMACEUTICAL TECHNOLOGY CO LTD 2011-11-23 CN disclosed
WO-2011143118-A2 ALCOHOL-RESISTANT FORMULATIONS CIMA LABS INC. (US) 2011-11-17 WO disclosed
CN-101420982-B Dry direct-compression fast disintegrating tablet TOA PHARMACEUTICALS CO LTD 2011-11-09 CN disclosed
US-20110268680-A1 HEAT STABLE PROTEIN INGREDIENTS UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2011-11-03 US disclosed
WO-2011127288-A2 METHODS AND USES OF NUR77 AND NUR77 AGONISTS TO MODULATE MACROPHAGES AND MONOCYTES, AND TREAT INFLAMMATION, INFLAMMATORY DISEASE AND CARDIOVASCULAR DISEASE LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2011-10-13 WO disclosed
EP-1695955-B1 COMPOUNDS HAVING LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISM AND USES THEREOF ONO PHARMACEUTICAL CO (JP) 2011-10-12 EP disclosed
WO-2011119185-A1 METHODS OF INHIBITING INFLAMMATION AND INFLAMMATORY DISEASES USING GAL-3BP (BTBD17B, LGALS3BP, GALECTIN-3 BINDING PROTEIN, MAC-2 BINDING PROTEIN) LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2011-09-29 WO disclosed
US-8026273-B2 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2011-09-27 US disclosed
EP-2366389-A1 Severe sepsis preventive therapeutic agent Takeda Pharmaceutical Company Limited (JP) 2011-09-21 EP disclosed
US-8003642-B2 Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2011-08-23 US disclosed
US-20110184034-A1 Severe sepsis preventive therapeutic agent TAKEDA PHARMACEUTICAL COMPANY LIMITED 2011-07-28 US disclosed
EP-1486491-B1 CARBOXYLIC ACID COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO (JP) 2011-07-13 EP disclosed
US-7968572-B2 Nitrogen-containing heterocyclic compound and pharmaceutical application thereof ONO PHARMACEUTICALS CO., LTD. (JP) 2011-06-28 US disclosed
US-20110152520-A1 NITROGENOUS HETEROCYCLIC DERIVATIVE AND MEDICINE CONTAINING THE SAME AS AN ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2011-06-23 US disclosed
CN-101056855-B Nitrogen-containing heterocyclic derivative and drug containing same as active ingredient ONO PHARMACEUTICAL CO 2011-06-15 CN disclosed
US-7960416-B2 Oil-in-water emulsion of a 1-carboxylate-6-arylsulfamoyl cyclohexene and synthetic and naturally occurring phospholipids; nitric oxide or cytokine prodution inhibitors; cardiovascular disorders, autoimmune dieseases, septic shock; improved stability during autoclave sterilization TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
CN-102065900-A Percutaneous absorption enhancer and transdermal preparation using the same TOA EIYO LTD (JP) 2011-05-18 CN disclosed
WO-2011057144-A2 METHODS FOR MODULATING LIF ACTIVITY, TREATING IMMUNE DISORDERS AND DISEASES, AND STIMULATINGS IMMUNE RESPONSES LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2011-05-12 WO disclosed
US-20110104241-A1 PERCUTANEOUS ABSORPTION ENHANCER AND TRANSDERMAL PREPARATION USING THE SAME TOA EIYO LTD. (JP) 2011-05-05 US disclosed
EP-2308562-A2 Azetidine ring compounds and drugs comprising the same Ono Pharmaceutical Co., Ltd. (JP) 2011-04-13 EP disclosed
US-20110070236-A1 USE OF IMMUNESUPPRESSANT RECEPTOR ONO PHARMACEUTICAL CO., LTD. (JP) 2011-03-24 US disclosed
EP-2298352-A1 PERCUTANEOUS ABSORPTION ENHANCER AND TRANSDERMAL PREPARATION USING THE SAME TOA Eiyo Ltd. (JP) 2011-03-23 EP disclosed
US-7910697-B2 Use of immunesuppressant receptor ONO PHARMACEUTICAL CO., LTD. (JP) 2011-03-22 US disclosed
US-20110052612-A1 SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2011-03-03 US disclosed
EP-1417975-B1 REMEDIES FOR DISEASES WITH BONE MASS LOSS HAVING EP4 AGONIST AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO (JP) 2011-03-02 EP disclosed
US-20110038855-A1 TRAIL AND METHODS OF MODULATING T CELL ACTIVITY AND ADAPTIVE IMMUNE RESPONSES USING TRAIL LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2011-02-17 US disclosed
WO-2011012715-A1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2011-02-03 WO disclosed
US-7875745-B2 {1-[(2S,3S)-2-(2,3-dihydro-1H-inden-2-ylmethyl)-3-(3,5-dimethoxy-4- methylphenyl)-3-hydroxylpropyl]-1H-pyrrol-3-yl}acetic acid; for urinary system disease selected from the group of prostatic hypertrophy, neurogenic bladder dysfunction disease, dysuria, pollakiuria, night urination and urodynia ONO PHARMACEUTICAL CO., LTD. (JP) 2011-01-25 US disclosed
US-20110015158-A1 METALLOENZYME INHIBITORS USING METAL BINDING MOIETIES IN COMBINATION WITH TARGETING MOIETIES VIAMET PHARMACEUTICALS, INC. (US) 2011-01-20 US disclosed
EP-1481969-B1 PIPERIDINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO (JP) 2011-01-19 EP disclosed
US-7858610-B2 Preventive and/or remedy for lower urinary tract diseases containing EP4 agonist ONO PHARMACEUTICAL CO., LTD. (JP) 2010-12-28 US disclosed
US-20100322978-A1 MEDICAL COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-23 US disclosed
CN-101921220-A Treat the EP that contains with the bone mass loss diseases associated 4Agonist is as the pharmaceutical composition of activeconstituents ONO PHARMACEUTICAL CO 2010-12-22 CN disclosed
EP-2260869-A2 Pharmaceutical product Takeda Pharmaceutical Company Limited (JP) 2010-12-15 EP disclosed
US-20100304998-A1 Chemical Proteomic Assay for Optimizing Drug Binding to Target Proteins MARQUETTE UNIVERSITY (US) 2010-12-02 US disclosed
US-20100305326-A1 Chemical Fragment Screening and Assembly Utilizing Common Chemistry for NMR Probe Introduction and Fragment Linkage MARQUETTE UNIVERSITY (US) 2010-12-02 US disclosed
EP-2255829-A2 Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising EP4 agonist as active ingredient Ono Pharmaceutical Co., Ltd. (JP) 2010-12-01 EP disclosed
EP-2255785-A2 Stable emulsion composition Takeda Pharmaceutical Company Limited (JP) 2010-12-01 EP disclosed
US-20100284991-A1 Methods for the Treatment and Diagnosis of Bone Mineral Density Related Diseases INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2010-11-11 US disclosed
WO-2010126960-A1 PYRROLOTRIAZINE COMPOUNDS LOCUS PHARMACEUTICALS, INC. (US) 2010-11-04 WO disclosed
EP-1010435-B1 NANOCAPSULE PREPARATIONS FOR TREATING INTRAARTICULAR DISEASES MARUHO K K (JP) 2010-11-03 EP disclosed
US-7820682-B2 LPA receptor antagonist ONO PHARMACEUTICAL CO., LTD. (JP) 2010-10-26 US disclosed
US-20100267665-A1 REMEDY FOR CORNEAL DISEASES TEIKA PHARMACEUTICAL CO., LTD. (JP) 2010-10-21 US disclosed
US-20100266539-A1 CHEMOKINE RECEPTOR ANTAGONIST AND MEDICAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2010-10-21 US disclosed
EP-2234608-A2 METALLOENZYME INHIBITORS USING METAL BINDING MOIETIES IN COMBINATION WITH TARGETING MOIETIES Viamet Pharmaceuticals, Inc. (US) 2010-10-06 EP disclosed
US-7807156-B1 Methods of treating OX40 mediated recall immune responses LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2010-10-05 US disclosed
US-20100249157-A2 LPA RECEPTOR ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2010-09-30 US disclosed
US-7803801-B2 Aminopyridine compounds having Syk inhibitory activity JAPAN TOBACCO, INC. (JP) 2010-09-28 US disclosed
US-20100233219-A1 INORGANIC NANOPARTICLE COMPROMISING AN ACTIVE SUBSTANCE IMMOBILIZED ON THE SURFACE AND A POLYMER FUJIFILM CORPORATION (JP) 2010-09-16 US disclosed
US-20100234368-A1 CONDENSED RING COMPOUND AND USE THEREOF TAKEUCHI JUN 2010-09-16 US disclosed
EP-2227560-A1 METHODS FOR THE TREATMENT AND DIAGNOSIS OF BONE MINERAL DENSITY RELATED DISEASES INSERM - Institut National de la Santé et de la Recherche Médicale (FR) 2010-09-15 EP disclosed
US-20100221259-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2010-09-02 US disclosed
US-20100216871-A1 USE OF COMPOUNDS HAVING CCR ANTAGONISM TSUCHIMORI NOBORU 2010-08-26 US disclosed
CN-101796039-A Phenylacetic acid compound ONO PHARMACEUTICAL CO 2010-08-04 CN disclosed
US-7763610-B2 Carboxylic acid derived benzoxazines as agents for the treatment of respiratory diseases ONO PHARMACEUTICAL CO., LTD. (JP) 2010-07-27 US disclosed
US-7759336-B2 Nitrogen-containing heterocyclic compounds and medicinal use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2010-07-20 US disclosed
EP-2206702-A1 Bicyclic compound, production and use thereof Tobira Therapeutics, Inc. (US) 2010-07-14 EP disclosed
EP-2206698-A1 Ethynylindole compounds ONO Pharmaceutical Co., Ltd. (JP) 2010-07-14 EP disclosed
CN-101775013-A Nitrogenous heterocyclic derivative and medicine containing the same as an active ingredient ONO PHARMACEUTICAL CO 2010-07-14 CN disclosed
CN-101759628-A Ethynylindole compounds ONO PHARMACEUTICAL CO 2010-06-30 CN disclosed
US-20100160647-A1 ETHYNYLINDOLE COMPOUNDS ONO PHARMACEUTICAL CO., LTD. (JP) 2010-06-24 US disclosed
US-20100143424-A1 CASEIN NANOPARTICLE FUJIFILM CORPORATION (JP) 2010-06-10 US disclosed
US-7732442-B2 Chemokine receptor antagonist and medical use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2010-06-08 US disclosed
US-7728023-B2 Indole compound and use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2010-06-01 US disclosed
US-20100130737-A1 Regulating Agent of GPR34 Receptor Function TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-05-27 US disclosed
US-7713998-B2 Nitrogenous heterocyclic compound and pharmaceutical use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2010-05-11 US disclosed
US-20100113388-A1 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2010-05-06 US disclosed
EP-2177513-A1 PHENYLACETIC ACID COMPOUND ONO Pharmaceutical Co., Ltd. (JP) 2010-04-21 EP disclosed
EP-2167647-A2 REGULATORY T CELLS AND METHODS OF MAKING AND USING SAME LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2010-03-31 EP disclosed
US-7683094-B2 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2010-03-23 US disclosed
US-20100069351-A1 SPIRO COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-03-18 US disclosed
US-20100063104-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF ONO PHARMACEUTICAL CO., LTD., (JP) 2010-03-11 US disclosed
EP-1423376-B1 BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF TOBIRA THERAPEUTICS INC (US) 2010-03-10 EP disclosed
US-20100029631-A1 CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2010-02-04 US disclosed
US-20100016381-A1 STABLE EMULSION COMPOSITION TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-01-21 US disclosed
US-20100015119-A1 EPITHELIUM-IMPROVING AGENT KOBAYASHI HARUZO 2010-01-21 US disclosed
US-20100010222-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DISEASES ASSOCIATED WITH DECREASE IN BONE MASS COMPRISING EP4 AGONIST AS ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2010-01-14 US disclosed
US-20090325956-A1 Aromatic amine derivative and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-12-31 US disclosed
US-20090325992-A1 COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2009-12-31 US disclosed
US-20090317833-A1 Screening Method HIROSHIMA UNIVERSITY (JP) 2009-12-24 US disclosed
US-20090304599-A1 Protein Nanoparticles and the Use of the Same FUJIFILM CORPORATION (JP) 2009-12-10 US disclosed
US-20090299265-A1 Electrode Assembly for Iontophoresis Having Shape-Memory Separator and Iontophoresis Device Using the Same TTI ELLEBEAU, INC. (JP) 2009-12-03 US disclosed
EP-2119446-A1 EPITHELIUM IMPROVING AGENT Kobayashi, Haruzo (JP) 2009-11-18 EP disclosed
US-20090280153-A1 electrical devices, anti-scarring agents, and therapeutic compositions ANGIOTECH INTERNATIONAL AG (CH) 2009-11-12 US disclosed
US-20090280148-A1 CASEIN NANOPARTICLE FUJIFILM CORPORATION (JP) 2009-11-12 US disclosed
US-20090275668-A1 Sprayable Gel-Type Skin/Mucosa-Adhesive Preparation and Administration System Using the Preparation TOKO YAKUHIN KOGYO DABUSHIKI KAISHA (JP) 2009-11-05 US disclosed
US-7608637-B2 Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising EP4 agonist as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2009-10-27 US disclosed
US-7601712-B2 Such as (1)-2-(4-chloro-3-((2-chloro-4-(((2S)-4-methyl-3,4-dihydro-2H-1,4-benzoxazin-2-ly)methoxy)benzoyl)amino)phenyl)-2-methylpropanoic acid; prostaglandin receptor agonists ONO PHARMACEUTICAL CO., LTD. (JP) 2009-10-13 US disclosed
US-20090247600-A1 REMEDY FOR CORNEAL DISEASES TEIKA PHARAMACEUTICAL CO., LTD. (JP) 2009-10-01 US disclosed
US-20090226500-A1 SUTURES AND ANTI-SCARRING AGENTS ANGIOTECH PHARMACEUTICALS, INC (CA) 2009-09-10 US disclosed
WO-2009105140-A2 METALLOENZYME INHIBITORS USING METAL BINDING MOIETIES IN COMBINATION WITH TARGETING MOIETIES VIAMET PHARMACEUTICALS, INC. (US) 2009-08-27 WO disclosed
US-20090209585-A1 CYCLOALKENE DERIVATIVES, PROCESS FOR PRODUCTION OF THE DERIVATIVES, AND USE OF THE SAME TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-08-20 US disclosed
US-7563822-B2 Agents for the prevention or treatment of renal diseases KISSEI PHARMACEUTICAL CO., LTD. (JP) 2009-07-21 US disclosed
US-20090155277-A1 Use of immunesuppressant receptor ONO PHARMACEUTICAL CO., LTD. (JP) 2009-06-18 US disclosed
WO-2009071661-A1 METHODS FOR THE TREATMENT AND DIAGNOSIS OF BONE MINERAL DENSITY RELATED DISEASES INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2009-06-11 WO disclosed
WO-2009073163-A1 AVIAN INFLUENZA ANTIBODIES, COMPOSITIONS, AND METHODS THEREOF AMERICAN TYPE CULTURE COLLECTION (ATCC) (US) 2009-06-11 WO disclosed
US-7541478-B2 Coumarin derivative and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-06-02 US disclosed
US-20090136470-A1 REGULATORY T CELLS AND METHODS OF MAKING AND USING SAME NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-05-28 US disclosed
CN-101443322-A Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient ONO PHARMACEUTICAL CO (JP) 2009-05-27 CN disclosed
US-20090131403-A1 NITROGENATED HETEROCYCLIC DERIVATIVE , AND PHARMACEUTICAL AGENT COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2009-05-21 US disclosed
US-7531170-B1 Methods of treating OX40 mediated recall immune responses and agents useful for identifying same LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2009-05-12 US disclosed
US-20090118255-A1 Crp Lowering Agent TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-05-07 US disclosed
EP-2055705-A1 COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF Ono Pharmaceutical CO., LTD. (JP) 2009-05-06 EP disclosed
CN-101426531-A Gel-type skin/mucosa-adhesive preparation for spraying and drug delivery system using the same TOKO YAKUHIN KOGYO KK (JP) 2009-05-06 CN disclosed
CN-101420982-A Dry direct-compression fast disintegrating tablet TOA PHARMACEUTICALS CO LTD (JP) 2009-04-29 CN disclosed
CN-101416943-A Ozagrel liposomes and preparation method thereof SHENYANG WANAIPULIDE MEDICAL T (CN) 2009-04-29 CN disclosed
US-20090105314-A1 Pharmaceutical Agent TAKEDA PHARMACEUTICAL COMPANY LIMITED 2009-04-23 US disclosed
CN-101415395-A Casein nanoparticle FUJIFILM CORP (JP) 2009-04-22 CN disclosed
US-7511159-B2 Azetidine ring compounds and drugs comprising the same ONO PHARMACEUTICAL CO., LTD. (JP) 2009-03-31 US disclosed
US-20090082333-A1 REMEDY FOR XANTHOMA NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2009-03-26 US disclosed
EP-2039681-A1 CYCLOALKENE DERIVATIVES, PROCESS FOR PRODUCTION OF THE DERIVATIVES, AND USE OF THE SAME Takeda Pharmaceutical Company Limited (JP) 2009-03-25 EP disclosed
US-20090074671-A1 DRUG-IMMOBILIZED INORGANIC NANOPARTICLE FUJIFILM CORPORATION (JP) 2009-03-19 US disclosed
US-20090062355-A1 Pharmaceutical Product TAKEDA PHARMACEUTICAL COMPANY LIMITED 2009-03-05 US disclosed
US-7495018-B2 Substituted 1,3-thiazole compounds, their production and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-02-24 US disclosed
US-20090042885-A1 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2009-02-12 US disclosed
US-20090030032-A1 Bicyclic Compound, Production and Use Thereof TAKEDA CHEMICAL INDUSTRIES LTD. (JP) 2009-01-29 US disclosed
EP-2018872-A1 PHARMACEUTICAL PRODUCT Takeda Pharmaceutical Company Limited (JP) 2009-01-28 EP disclosed
EP-2018855-A1 PHARMACEUTICAL AGENT Takeda Pharmaceutical Company Limited (JP) 2009-01-28 EP disclosed
EP-2014305-A1 SPRAYABLE GEL-TYPE SKIN/MUCOSA-ADHESIVE PREPARATION AND ADMINISTRATION SYSTEM USING THE PREPARATION Toko Yakuhin Kogyo Kabushiki Kaisha (JP) 2009-01-14 EP disclosed
EP-2011472-A1 CASEIN NANOPARTICLE FUJIFILM Corporation (JP) 2009-01-07 EP disclosed
US-20090004278-A1 Enzymatically Crosslinked Protein Nanoparticles FUJIFILM CORPORATION (JP) 2009-01-01 US disclosed
WO-2008157394-A2 REGULATORY T CELLS AND METHODS OF MAKING AND USING SAME LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2008-12-24 WO disclosed
CN-101321745-A Nitrogen-containing heterocyclic compound and pharmaceutical application thereof ONO PHARMACEUTICAL CO (JP) 2008-12-10 CN disclosed
EP-1997902-A1 SCREENING METHOD Hiroshima University (JP) 2008-12-03 EP disclosed
US-20080293764-A1 LPA RECEPTOR ANTAGONIST ONO PHARMACEUTICAL CO., LTD. 2008-11-27 US disclosed
EP-1995246-A1 NITROGENATED HETEROCYCLIC DERIVATIVE, AND PHARMACEUTICAL AGENT COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2008-11-26 EP disclosed
US-20080287467-A1 Therapeutic Agent for Respiratory Diseases ONO PHARMACEUTICAL CO., LTD. (JP) 2008-11-20 US disclosed
CN-101302180-A 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient ONO PHARMACEUTICAL CO (JP) 2008-11-12 CN disclosed
WO-2008134354-A1 TNF-α PRODUCTION INHIBITOR ARRAY BIOPHARMA, INC. (US) 2008-11-06 WO disclosed
US-20080260849-A1 COMPOSITION FOR TRANSMUCOSAL ABSORPTION FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
EP-1978930-A2 SUTURES AND ANTI-SCARRING AGENTS Angiotech Pharmaceuticals, Inc. (CA) 2008-10-15 EP disclosed
EP-1968649-A1 PROTEIN NANOPARTICLES AND THE USE OF THE SAME Fujifilm Corporation (JP) 2008-09-17 EP disclosed
US-7425567-B2 Piperidine derivative compounds and drugs containing the compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-09-16 US disclosed
US-20080188532-A1 Indole Compound and Use Thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2008-08-07 US disclosed
US-7402605-B2 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-07-22 US disclosed
US-20080167314-A1 Condensed Imidazole Compound And Use Thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-07-10 US disclosed
EP-1941928-A1 ELECTRODE STRUCTURE FOR IONTOPHORESIS USED TO ADMINISTER DRUG ENCLOSED IN NANOPARTICLE AND IONTOPHORESIS DEVICE MAKING USE OF THE SAME TTI ELLEBEAU, INC. (JP) 2008-07-09 EP disclosed
EP-1941929-A1 ELECTRODE STRUCTURE FOR IONTOPHORESIS COMPRISING SHAPE MEMORY SEPARATOR, AND IONTOPHORESIS APPARATUS COMPRISING THE SAME TTI ELLEBEAU, INC. (JP) 2008-07-09 EP disclosed
US-20080161287-A1 Bicyclic compound, production and use thereof TAKEDA PHARMACEUTICAL COMPANY, LTD (JP) 2008-07-03 US disclosed
CN-101212986-A stable emulsified composition TAKEDA PHARMACEUTICAL (JP) 2008-07-02 CN disclosed
EP-1932840-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2008-06-18 EP disclosed
CN-101203243-A Therapeutic agent for xanthoma NAT UNIV CORP KOBE UNIV (JP) 2008-06-18 CN disclosed
EP-1927353-A1 REMEDY FOR CORNEAL DISEASES Teika Pharmaceutical Co., Ltd. (JP) 2008-06-04 EP disclosed
US-7378428-B2 Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-05-27 US disclosed
US-7371772-B2 Bicyclic compound, production and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-05-13 US disclosed
CN-101166734-A Novel aminopyridine compounds having Syk inhibitory activity JAPAN TOBACCO INC (JP) 2008-04-23 CN disclosed
US-20080081825-A1 Nitrogen-Containing Heterocyclic Compounds and Medicinal Use Thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2008-04-03 US disclosed
US-7351705-B2 Carboxylic acid compounds and a pharmaceutical agent comprising the compound as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-04-01 US disclosed
US-20080057074-A1 Nitrogenous Heterocylic Derivative and Medicine Containing the Same as an Active Ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-03-06 US disclosed
EP-1889839-A1 Bicyclic compound, production and use as HIV inhibitors Takeda Pharmaceutical Company Limited (JP) 2008-02-20 EP disclosed
EP-1889632-A1 REMEDY FOR XANTHOMA National University Corp. Kobe University (JP) 2008-02-20 EP disclosed
EP-1889622-A1 SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2008-02-20 EP disclosed
CN-101128424-A Indole compound and use thereof ONO PHARMACEUTICAL CO (JP) 2008-02-20 CN disclosed
US-20080033033-A1 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. 2008-02-07 US disclosed
US-20080027094-A1 Tropane Compounds and Pharmaceutical Compositions Comprising the Same as an Active Ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-01-31 US disclosed
US-20080021021-A1 Preventive And/Or Remedy For Lower Urinary Tract Diseases Containing Ep4 Agonist ONO PHARMACEUTICAL CO., LTD. (JP) 2008-01-24 US disclosed
EP-1206937-B1 NITROIMIDAZOLE EXTERNAL PREPARATIONS FOR THE TREATMENT OF ATOPIC DERMATITIS SHOEI CO LTD (JP) 2008-01-23 EP disclosed
EP-1875926-A1 STABLE EMULSION COMPOSITION Takeda Pharmaceutical Company Limited (JP) 2008-01-09 EP disclosed
US-20070270429-A1 Function Inhibitor of Effector Cell ONO PHARMACEUTICAL CO., LTD. (JP) 2007-11-22 US disclosed
US-20070265308-A1 Nitrogenous Heterocyclic Compound and Pharmaceutical Use Thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2007-11-15 US disclosed
EP-1854793-A1 NOVEL AMINOPYRIDINE COMPOUND WITH Syk INHIBITORY ACTIVITY Japan Tobacco, Inc. (JP) 2007-11-14 EP disclosed
EP-1852420-A1 INDOLE COMPOUND AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2007-11-07 EP disclosed
US-7291331-B1 Methods of treating OX40 medicated recall immune responses LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) 2007-11-06 US disclosed
US-7291644-B2 Indole derivatives ONO PHARMACEUTICALS CO., LTD. (JP) 2007-11-06 US disclosed
US-20070254886-A1 Chemokine Receptor Antagonist and Medical Use Thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2007-11-01 US disclosed
EP-1849465-A1 AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR Takeda Pharmaceutical Company Limited (JP) 2007-10-31 EP disclosed
US-7288654-B2 Fused-ring pyridine derivative, process for producing the same, and use TAKEDA PHARMACEUTICAL COMPANY LTD (JP) 2007-10-30 US disclosed
US-20070249695-A1 Preventive and/or Therapeutic Agents for Meniere's Disease KAZUYA KAWATA (JP) 2007-10-25 US disclosed
WO-2007116951-A1 DRUG-IMMOBILIZED INORGANIC NANOPARTICLE FUJIFILM CORPORATION (JP) 2007-10-18 WO disclosed
US-20070244079-A1 PREVENTIVE/REMEDY FOR ALLERGIC DISEASES AJINOMOTO CO., INC. (JP) 2007-10-18 US disclosed
WO-2007116954-A2 INORGANIC NANOPARTICLE COMPRISING AN ACTIVE SUBSTANCE IMMOBILIZED ON THE SURFACE AND A POLYMER FUJIFILM CORPORATION (JP) 2007-10-18 WO disclosed
CN-101056855-A Nitrogen-containing heterocyclic derivative and drug containing same as active ingredient ONO PHARMACEUTICAL CO (JP) 2007-10-17 CN disclosed
EP-1832588-A1 CONDENSED IMIDAZOLE COMPOUND AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2007-09-12 EP disclosed
CN-101035520-A CRP lowering agent TAKEDA PHARMACEUTICAL (JP) 2007-09-12 CN disclosed
EP-1829876-A1 NITROGENEOUS TRICYCLIC COMPOUND Asahi Kasei Pharma Corporation (JP) 2007-09-05 EP disclosed
CN-101023936-A A medicine for preventing ischemic disease in a diabetic patient MITSUBISHI PHARMA CORP (JP) 2007-08-29 CN disclosed
US-7262185-B2 Benzazepine derivative, process for producing the same, and use TAKEDA CHEMICAL INDUSTRIES LTD. (JP) 2007-08-28 US disclosed
US-20070197636-A1 Coumarin Derivative And Use Thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-08-23 US disclosed
EP-1818053-A1 PREVENTIVE/REMEDY FOR ALLERGIC DISEASES Ajinomoto Co., Inc. (JP) 2007-08-15 EP disclosed
US-7256211-B1 8-azaprostaglandin derivatives and medical use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2007-08-14 US disclosed
WO-2007089878-A2 SUTURES AND ANTI-SCARRING AGENTS ANGIOTECH PHARMACEUTICALS, INC. (CA) 2007-08-09 WO disclosed
WO-2007086613-A1 ENZYMATICALLY CROSSLINKED PROTEIN NANOPARTICLES FUJIFILM CORPORATION (JP) 2007-08-02 WO disclosed
US-20070179154-A1 Coumarin derivatives, process for their production and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-08-02 US disclosed
EP-1810972-A1 NITROGENOUS HETEROCYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2007-07-25 EP disclosed
US-20070167459-A1 Nitrogen-containing heterocyclic compounds and medicinal use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2007-07-19 US disclosed
EP-1806147-A1 USE OF IMMUNESUPPRESSANT RECEPTOR ONO PHARMACEUTICAL CO., LTD. (JP) 2007-07-11 EP disclosed
WO-2007072982-A1 PROTEIN NANOPARTICLES AND THE USE OF THE SAME FUJIFILM CORPORATION (JP) 2007-06-28 WO disclosed
US-20070149595-A1 Compounds having lysophosphatidic acid receptor antagonism and uses thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2007-06-28 US disclosed
CN-1323074-C Piperidine derivative compound and drug containing the same compound as active ingredient ONO PHARMACEUTICAL CO (JP) 2007-06-27 CN disclosed
US-20070135402-A1 Azetidine ring compounds and drugs comprising the same ONO PHARMACEUTICAL CO., LTD. (JP) 2007-06-14 US disclosed
US-20070135754-A1 ELECTRODE ASSEMBLY FOR IONTOPHORESIS FOR ADMINISTERING ACTIVE AGENT ENCLOSED IN NANOPARTICLE AND IONTOPHORESIS DEVICE USING THE SAME TTI ELLEBEAU, INC. (JP) 2007-06-14 US disclosed
EP-1790637-A1 NITROGENOUS HETEROCYCLIC DERIVATIVE AND MEDICINE CONTAINING THE SAME AS AN ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2007-05-30 EP disclosed
EP-1785421-A1 TROPAN COMPOUND ONO PHARMACEUTICAL CO., LTD. (JP) 2007-05-16 EP disclosed
EP-1776096-A2 CRP LOWERING AGENT Takeda Pharmaceutical Company Limited (JP) 2007-04-25 EP disclosed
EP-1242068-A4 ENDOGENOUS NITRIC OXIDE SYNTHESIS UNDER CONDITIONS OF LOW OXYGEN TENSION NITROMED INC (US) 2007-04-25 EP disclosed
CN-1950352-A Coumarin derivative and use thereof TAKEDA PHARMACEUTICAL (JP) 2007-04-18 CN disclosed
US-7199124-B2 JNK inhibitor TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-04-03 US disclosed
US-20070060595-A1 Novel fused heterocyclic compound and use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2007-03-15 US disclosed
CN-1304001-C Nitroimidazole external preparations for dermatosis SHOEI CO LTD (JP) 2007-03-14 CN disclosed
US-20070021711-A1 Iontophoresis device controlling administration amount and administration period of plurality of drugs Transcutaneous Technologies, Inc. (JP) 2007-01-25 US disclosed
US-20070010529-A1 Nitrogenous heterocyclic compounds and medical use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2007-01-11 US disclosed
EP-1741702-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2007-01-10 EP disclosed
CN-1893977-A By EP4Medicine with agonist as active component for treating diseases related to bone loss ONO PHARMACEUTICAL CO (JP) 2007-01-10 CN disclosed
US-20070004716-A1 Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2007-01-04 US disclosed
US-20060293343-A1 Pyrimidine derivatives ASAHI KASEI PHARMA CORPORATION (JP) 2006-12-28 US disclosed
US-7153852-B2 Indole compounds, process for producing the same and drugs containing the same as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2006-12-26 US disclosed
WO-2006121518-A2 ELECTRICAL DEVICES, ANTI-SCARRING AGENTS, AND THERAPEUTIC COMPOSITIONS ANGIOTECH INTERNATIONAL AG (CH) 2006-11-16 WO disclosed
WO-2006121522-A2 IMPLANTABLE SENSORS AND PUMPS, ANTI-SCARRING AGENTS, AND THERAPEUTIC COMPOSITIONS ANGIOTECH INTERNATIONAL AG (CH) 2006-11-16 WO disclosed
EP-1720850-A1 COUMARIN DERIVATIVE AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2006-11-15 EP disclosed
EP-1254659-B1 STABLE EMULSION COMPOSITIONS TAKEDA PHARMACEUTICAL (JP) 2006-11-15 EP disclosed
US-7135495-B2 Indole derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 2006-11-14 US disclosed
US-20060247266-A1 Nitrogen-containing tricyclic compounds ASAHI KASEI PHARMA CORPORATION (JP) 2006-11-02 US disclosed
US-20060228352-A1 TRAIL and methods of modulating T cell activity and adaptive immune responses using TRAIL NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-10-12 US disclosed
CN-1845911-A Condensed ring compound and use thereof ONO PHARMACEUTICAL CO (JP) 2006-10-11 CN disclosed
US-20060205731-A1 Novel aminopyridine compounds having Syk inhibitory activity JAPAN TOBACCO INC. (JP) 2006-09-14 US disclosed
US-7105572-B2 Stable emulsion compositions TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-09-12 US disclosed
EP-1698375-A1 AZETIDINE RING COMPOUNDS AND DRUGS COMPRISING THE SAME ONO PHARMACEUTICAL CO., LTD. (JP) 2006-09-06 EP disclosed
US-20060194864-A1 Indole derivatives ONO PHARMACEUTICAL CO., LTD. 2006-08-31 US disclosed
US-20060194797-A1 Condensed ring compound and use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2006-08-31 US disclosed
EP-1695955-A1 COMPOUNDS HAVING LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISM AND USES THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2006-08-30 EP disclosed
US-20060178359-A1 Tricyclic compound, process for producing the same, and use SYNGENTA CROP PROTECTION AG (CH) 2006-08-10 US disclosed
US-20060160864-A1 Acrylamide derivative, process for producing the same, and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-07-20 US disclosed
US-20060148830-A1 Lpa receptor antagonist ONO PHARMACEUTICAL CO., LTD. 2006-07-06 US disclosed
US-20060148844-A1 Pharmaceutical composition for treatment of disease due to vascular constriction or vasodilation ONO PHARMACEUTICAL CO., LTD 2006-07-06 US disclosed
EP-1671962-A1 NOVEL FUSED HETEROCYCLIC COMPOUND AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2006-06-21 EP disclosed
US-20060128810-A1 Remedies for allergic diseases KYOTO UNIVERSITY (JP) 2006-06-15 US disclosed
EP-1666473-A1 CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2006-06-07 EP disclosed
EP-1661892-A1 CONDENSED RING COMPOUND AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2006-05-31 EP disclosed
EP-1661889-A1 CHEMOKINE RECEPTOR ANTAGONIST AND MEDICAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2006-05-31 EP disclosed
US-20060111446-A1 5-Amidino-N-(2-aminophenethyl)-2-hydroxybenzenesulfonamide derivative, medicinal composition containing the same, pharmaceutical use thereof, and intermediate therefor KISSEI PHARMACEUTICAL CO., LTD. 2006-05-25 US disclosed
US-20060100197-A1 Fused-ring pyridine derivative, process for producing the same, and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-05-11 US disclosed
US-20060089353-A1 Indole derivative compounds and drugs containing the compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2006-04-27 US disclosed
US-7022689-B2 5-amidino-n-(2-aminophenethyl)-n-hydroxy-benzenesulffonamide derivative, medical composition containing the same, pharmaceutical use thereof and intermediate therefor KISSEI PHARMACEUTICAL CO., LTD. (JP) 2006-04-04 US disclosed
US-20060058288-A1 Severe sepsis preventive therapeutic agent TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2006-03-16 US disclosed
WO-2006016681-A2 CRP LOWERING AGENT TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-02-16 WO disclosed
US-20060035865-A1 Lipid-rich plaque regressing agents TERASHITA ZEN-ICHI 2006-02-16 US disclosed
EP-1623721-A1 EFFECTOR CELL FUNCTION INHIBITOR ONO PHARMACEUTICAL CO., LTD. (JP) 2006-02-08 EP disclosed
US-20060004010-A1 Ccr4 antagonist and medical use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2006-01-05 US disclosed
US-6974806-B2 Lipid-rich plaque inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-12-13 US disclosed
EP-1600440-A1 INDOLE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2005-11-30 EP disclosed
EP-1593680-A1 FUSED-RING PYRIDINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Pharmaceutical Company Limited (JP) 2005-11-09 EP disclosed
EP-1593673-A1 ACRYLAMIDE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Pharmaceutical Company Limited (JP) 2005-11-09 EP disclosed
EP-1593681-A1 TRICYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Pharmaceutical Company Limited (JP) 2005-11-09 EP disclosed
US-20050245537-A1 Use of compounds having ccr antagonism TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-11-03 US disclosed
EP-1586564-A1 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICINAL USES THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2005-10-19 EP disclosed
US-20050222138-A1 Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2005-10-06 US disclosed
US-20050222216-A1 Carboxyoic acid compounds and drugs containing the compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2005-10-06 US disclosed
WO-2005082879-A1 COUMARIN DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-09-09 WO disclosed
EP-1571146-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2005-09-07 EP disclosed
CN-1658863-A Medicine for preventing and treating severe sepsis TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2005-08-24 CN disclosed
EP-1563845-A1 REMEDIES FOR ALLERGIC DISEASES ONO PHARMACEUTICAL CO., LTD. (JP) 2005-08-17 EP disclosed
CN-1653046-A 8-azaprostaglandin derivative compound and medicine containing the same as active ingredient ONO PHARMACEUTICAL CO (JP) 2005-08-10 CN disclosed
CN-1649841-A Piperidine derivative compound and drug containing the same compound as active ingredient ONO PHARMACEUTICAL CO (JP) 2005-08-03 CN disclosed
EP-1044974-B1 N-HYDROXYUREA DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME NIKKEN CHEMICALS CO LTD (JP) 2005-07-20 EP disclosed
EP-1553075-A1 LPA RECEPTOR ANTAGONISTS ONO PHARMACEUTICAL CO., LTD. (JP) 2005-07-13 EP disclosed
US-20050147672-A1 Tablets quickly disintegrating in mouth OHMORI SHINJI (JP) 2005-07-07 US disclosed
EP-1541563-A1 CCR4 ANTAGONIST AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2005-06-15 EP disclosed
US-20050124577-A1 8-Azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2005-06-09 US disclosed
US-20050107354-A1 active ingredient a 5-amidino-2-hydroxybenzenesulfonamide derivative or a pharmaceutical acceptable salt thereof; excellent inhibitory effect on mesangial cell proliferation and decreasing effect on urine protein excretion KISSEI PHARMACEUTICAL CO., LTD. (JP) 2005-05-19 US disclosed
CN-1615305-A Coumarin derivatives, process for their production and use thereof TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2005-05-11 CN disclosed
US-20050085509-A1 Piperidin-2-one derivative compounds and drugs containing these compounds as the active ingredient ONO PHARMACEUTICAL CO. LTD. (JP) 2005-04-21 US disclosed
US-20050080107-A1 Piperidine derivative compounds and drugs containing the compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2005-04-14 US disclosed
US-20050080113-A1 Medicinal compositions TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-04-14 US disclosed
EP-1522314-A1 REMEDIES FOR DISEASES CAUSED BY VASCULAR CONTRACTION OR DILATION ONO PHARMACEUTICAL CO., LTD. (JP) 2005-04-13 EP disclosed
CN-1578767-A Piperidin-2-one derivative compounds and drugs containing these compounds as the active ingredient ONO PHARMACEUTICAL CO (JP) 2005-02-09 CN disclosed
US-20050020634-A1 Coumarin derivatives, process for their production and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-01-27 US disclosed
US-20050020686-A1 Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient ONO PHARMACEUTICAL CO. LTD. (JP) 2005-01-27 US disclosed
US-20050014787-A1 5-amidino-2-hydroxybenzenesulfonamide derivatives medicinal compoistions containing the same medicinal use thereof and intermediates in the production thereof KISSEI PHARMACEUTICAL CO., LTD. (JP) 2005-01-20 US disclosed
EP-1498125-A1 USE OF COMPOUNDS HAVING CCR ANTAGONISM Takeda Pharmaceutical Company Limited (JP) 2005-01-19 EP disclosed
EP-1495756-A1 SEVERE SEPSIS PREVENTIVE THERAPEUTIC AGENT Takeda Chemical Industries, Ltd. (JP) 2005-01-12 EP disclosed
US-20050004096-A1 Indole derivatives, process for producing the same and drugs containing the same as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2005-01-06 US disclosed
US-20050004097-A1 Indole derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 2005-01-06 US disclosed
US-20040259876-A1 Bicyclic compound, production and use thereof TOBIRA THERAPEUTICS, INC. 2004-12-23 US disclosed
US-20040253276-A1 Stable emulsion composition TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-12-16 US disclosed
EP-1486491-A1 CARBOXYOIC ACID COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2004-12-15 EP disclosed
US-20040242455-A1 5-amidino-n-(2-aminophenethyl)-n-hydroxy-benzenesulffonamide derivative, medical composition containing the same, pharmaceutical use thereof and intermediate therefor KISSEI PAHRMACEUTICAL CO., LTD. (JP) 2004-12-02 US disclosed
US-20040242687-A1 Thrombus/thrombogenesis inhibitors MITSUBISHI TANABE PHARMA CORPORATION (JP) 2004-12-02 US disclosed
EP-1481976-A1 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2004-12-01 EP disclosed
EP-1481969-A1 PIPERIDINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2004-12-01 EP disclosed
US-20040235794-A1 Remedies for respiratory diseases comprising sphingosine-1-phosphate receptor controller ONO PHARMACEUTICAL CO., LTD. (JP) 2004-11-25 US disclosed
US-20040235822-A1 Benzazepine derivative, process for producing the same, and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-11-25 US disclosed
US-20040235955-A1 Remedies for pruritus ONO PHARMACEUTICAL CO., LTD. (JP) 2004-11-25 US disclosed
EP-1471064-A1 COUMARIN DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-10-27 EP disclosed
EP-1447401-A1 PIPERIDIN-2-ONE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2004-08-18 EP disclosed
EP-1443041-A1 5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF Kissei Pharmaceutical Co., Ltd. (JP) 2004-08-04 EP disclosed
US-20040137052-A1 mixture of a drug having anti-allergy, anti-histamine, anti-inflammatory, anti-PAF (platelet-aggregating factor) or eosinophile chemotaxis inhibiting activity and an acid; dosage form; excellent in the digestive tract absorbability and stability TAKEDA CHEMICAL INDUSARIES LTD. (JP) 2004-07-15 US disclosed
EP-1430890-A1 THROMBUS/THROMBOGENESIS INHIBITORS Mitsubishi Pharma Corporation (JP) 2004-06-23 EP disclosed
EP-1426059-A1 REMEDIES FOR PRURITUS ONO PHARMACEUTICAL CO., LTD. (JP) 2004-06-09 EP disclosed
EP-1424335-A1 INDOLE DERIVATIVES ONO PHARMACEUTICAL CO., LTD. (JP) 2004-06-02 EP disclosed
EP-1424325-A1 INDOLE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2004-06-02 EP disclosed
EP-1423376-A1 BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-06-02 EP disclosed
EP-1424078-A1 REMEDIES FOR RESPIRATORY DISEASES COMPRISING SPHINGOSINE-1-PHOSPHATE RECEPTOR CONTROLLER ONO PHARMACEUTICAL CO., LTD. (JP) 2004-06-02 EP disclosed
EP-1422228-A1 BENZAZEPINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Chemical Industries, Ltd. (JP) 2004-05-26 EP disclosed
EP-1420783-A1 STABLE EMULSION COMPOSITION Takeda Chemical Industries, Ltd. (JP) 2004-05-26 EP disclosed
US-20040097555-A1 Concomitant drugs TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-05-20 US disclosed
EP-1417975-A1 REMEDIES FOR DISEASES WITH BONE MASS LOSS HAVING EP sb 4 /sb AGONIST AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2004-05-12 EP disclosed
EP-1415983-A1 5-AMIDINO-N-(2-AMINOPHENETHYL)-HYDROXYBENZENESULFONAMIDE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE THEREFOR Kissei Pharmaceutical Co., Ltd. (JP) 2004-05-06 EP disclosed
US-20040063685-A1 Cycloalkene antisepsis drug with antibacterial, antifungal, nonsteroidal antiinflammatory, steroid and/or anticoagulant agents TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-04-01 US disclosed
US-20040063946-A1 Jnk inhibitor TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-04-01 US disclosed
EP-1402900-A1 MEDICINAL COMPOSITIONS Takeda Chemical Industries, Ltd. (JP) 2004-03-31 EP disclosed
US-20040053973-A1 Substituted 1,3-thiazole compounds, their production and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-03-18 US disclosed
US-20030232809-A1 Lipid-rich plaque inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2003-12-18 US disclosed
EP-1364949-A1 JNK INHIBITOR Takeda Chemical Industries, Ltd. (JP) 2003-11-26 EP disclosed
WO-2003014105-A9 BICYCLIC COMPOUND, PRODUCTION AND USE AS HIV INHIBITORS TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-11-20 WO disclosed
US-20030212114-A1 Stable emulsion compositions TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2003-11-13 US disclosed
EP-1354603-A1 CONCOMITANT DRUGS Takeda Chemical Industries, Ltd. (JP) 2003-10-22 EP disclosed
EP-1348443-A1 COMBINATION DRUGS Takeda Chemical Industries, Ltd. (JP) 2003-10-01 EP disclosed
CN-1441794-A Lipid-rich plaque degrading agent TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-09-10 CN disclosed
US-20030161879-A1 Tablets quickly disintegrating in mouth TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2003-08-28 US disclosed
US-20030092754-A1 External preparation for skin diseases containing nitroimidazole SHOEI CO., LTD. (JP) 2003-05-15 US disclosed
EP-1302470-A1 LIPID-RICH PLAQUE INHIBITORS Takeda Chemical Industries, Ltd. (JP) 2003-04-16 EP disclosed
US-20030050305-A1 Thromboxane inhibitors, compositions and methods of use NITROMED, INC. 2003-03-13 US disclosed
WO-2003014105-A1 BICYCLIC COMPOUND, PRODUCTION AND USE AS HIV INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-02-20 WO disclosed
WO-2003013513-A1 STABLE EMULSION COMPOSITION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-02-20 WO disclosed
EP-1268474-A2 SUBSTITUTED 1,3-THIAZOLE COMPOUNDS, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 2003-01-02 EP disclosed
EP-1254659-A1 STABLE EMULSION COMPOSITIONS Takeda Chemical Industries, Ltd. (JP) 2002-11-06 EP disclosed
EP-1242068-A1 ENDOGENOUS NITRIC OXIDE SYNTHESIS UNDER CONDITIONS OF LOW OXYGEN TENSION Nitromed, Inc. (US) 2002-09-25 EP disclosed
CN-1361688-A External preparation for skin diseases containing nitroimidazole SHOEI CO LTD (JP) 2002-07-31 CN disclosed
EP-1206937-A1 NITROIMIDAZOLE EXTERNAL PREPARATIONS FOR DERMATOSIS SHOEI CO., LTD. (JP) 2002-05-22 EP disclosed
WO-2001089519-A1 THROMBOXANE INHIBITORS, COMPOSITIONS AND METHODS OF USE RELATED APPLICATIONS NITROMED, INC. (US) 2001-11-29 WO disclosed
WO-2001074811-A2 SUBSTITUTED 1,3-THIAZOLE COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-10-11 WO disclosed
US-6291482-B1 THROMBOXANE SYNTHASE INHIBITORY ANTI-INFLAMMATORY DRUG COMPRISING N-HYDROXY-N-(6-(3-PYRIDYMETHYL)-2H-1-BENZOPYRAN-3-YLMETHYL)URE A; ANTIALLERGIC, ANTIASTHMATIC NIKKEN CHEMICALS CO., LTD (JP) 2001-09-18 US disclosed
WO-2001032167-A1 ENDOGENOUS NITRIC OXIDE SYNTHESIS UNDER CONDITIONS OF LOW OXYGEN TENSION NITROMED, INC. (US) 2001-05-10 WO disclosed
EP-1010435-A1 NANOCAPSULE PREPARATIONS FOR TREATING INTRAARTICULAR DISEASES Maruho K.K. (JP) 2000-06-21 EP disclosed
US-6028094-A Agent for prevention and suppression of dry coughing caused by angiotensin converting enzyme inhibitors KISSEI PHARMACEUTICAL CO., LTD. (JP) 2000-02-22 US disclosed
US-6028094-A Agent for prevention and suppression of dry coughing caused by angiotensin converting enzyme inhibitors KISSEI PHARMACEUTICAL CO., LTD. (JP) 2000-02-22 US disclosed
EP-0665009-B1 CRYSTALLINE CONDITION DISLOCATING METHOD NIPPON SHINYAKU CO LTD (JP) 2000-02-16 EP disclosed
EP-0875254-A1 AGENT FOR PREVENTION AND DEPRESSION OF DRY COUGHING CAUSED BY ANGIOTENSIN CONVERTING ENZYME INHIBITORS KISSEI PHARMACEUTICAL CO., LTD. (JP) 1998-11-04 EP disclosed
EP-0875254-A1 AGENT FOR PREVENTION AND DEPRESSION OF DRY COUGHING CAUSED BY ANGIOTENSIN CONVERTING ENZYME INHIBITORS KISSEI PHARMACEUTICAL CO., LTD. (JP) 1998-11-04 EP disclosed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US disclosed
WO-1997022362-A1 AGENT FOR PREVENTION AND DEPRESSION OF DRY COUGHING CAUSED BY ANGIOTENSIN CONVERTING ENZYME INHIBITORS KISSEI PHARMACEUTICAL CO., LTD. (JP) 1997-06-26 WO disclosed
US-5602140-A CAUSED BY LEUKOCYTES JAPAN ENERGY CORPORATION (JP) 1997-02-11 US disclosed
EP-0675124-A2 Purine derivatives and suppressants for inflammatory diseases JAPAN ENERGY CORPORATION (JP) 1995-10-04 EP disclosed
EP-0665009-A1 CRYSTALLINE CONDITION DISLOCATING METHOD NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-08-02 EP disclosed
EP-0294814-B1 Treating agents for renal diseases DAIICHI SEIYAKU CO (JP) 1994-01-12 EP disclosed
EP-0298465-B1 ANTIDIABETIC AGENT DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1993-02-17 EP disclosed
US-4942171-A The compound, 6-(1-imidazolyl methyl)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid and salts thereof having antidiabetic activity DAIICHI SEIYAKU CO., LTD. (JP) 1990-07-17 US disclosed
EP-0135177-B1 BENZOCYCLOALKANE DERIVATIVES DAIICHI SEIYAKU CO., LTD. (JP) 1989-12-06 EP disclosed
EP-0298465-A2 Antidiabetic agent DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1989-01-11 EP disclosed
EP-0294814-A2 Treating agents for renal diseases DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1988-12-14 EP disclosed
US-4777257-A CARDIOVASCULAR DISORDERS DAIICHI SEIYAKU CO., LTD. (JP) 1988-10-11 US disclosed
US-4665188-A Certain [(1-imidazolyl)-lower-alkylene]-tetrahydronaphthalenecarboxylic acids or corresponding idan-carboxylic acids which are thromboxane A2 DAIICHI SEIYAKU CO., LTD. (JP) 1987-05-12 US disclosed
US-4607046-A THROMBOXANE SYNTHETASE INHIBITOR KISSEI PHARMACEUTICAL CO., LTD. (JP) 1986-08-19 US disclosed
EP-0135177-A2 Benzocycloalkane derivatives DAIICHI SEIYAKU CO., LTD. (JP) 1985-03-27 EP disclosed
EP-0058079-B1 4-(1-IMIDAZOLYLMETHYL)CINNAMIC ACID HYDROCHLORIDE MONOHYDRATE, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Kissei Pharmaceutical Co. Ltd. (JP) 1985-01-23 EP disclosed
EP-0058079-A2 4-(1-Imidazolylmethyl)cinnamic acid hydrochloride monohydrate, method of preparation thereof, and pharmaceutical composition containing same Kissei Pharmaceutical Co. Ltd. (JP) 1982-08-18 EP disclosed
JP-S57131769-A 4-(1-IMIDAZOLYLMETHYL)CINNAMIC ACID HYDROCHLORIDE MONOHYDRATE, ITS PREPARATION AND DRUG CONTAINING THE SAME KISSEI PHARMACEUT CO LTD 1982-08-14 JP disclosed
US-4226878-A ANTIINFLAMMATORY, HYPOTENSIVES, ANTIHISTAMINES KISSEI PHARMACEUTICAL CO., LTD. (JP) 1980-10-07 US disclosed
US-4226878-A ANTIINFLAMMATORY, HYPOTENSIVES, ANTIHISTAMINES KISSEI PHARMACEUTICAL CO., LTD. (JP) 1980-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160250238-A1 Method for the Prophylaxis or Treatment of Systemic Lupus Erythematosus and/or Lupus Nephritis SSB, ME1, SLC16A1 TBXAS1 4325/4885CYP1A2 3133/4885USP2 3352/4885
US-20100234368-A1 CONDENSED RING COMPOUND AND USE THEREOF CYSLTR2, CYSLTR1, LTB4R2 TBXAS1 97/4885CYP1A2 338/4885USP2 941/4885
US-20060194864-A1 Indole derivatives IDO1, IDO2, PTGIR TBXAS1 286/4885CYP1A2 1314/4885USP2 2056/4885
US-10973767-B2 Oral drug dosage form comprising drug in the form of nanoparticles CYP2D6, CYP3A5, CYP3A7 TBXAS1 3657/4885CYP1A2 30/4885USP2 2634/4885
US-20040259876-A1 Bicyclic compound, production and use thereof CCR5, CCR1, CCR2 TBXAS1 759/4885CYP1A2 1097/4885USP2 4647/4885
US-20070265308-A1 Nitrogenous Heterocyclic Compound and Pharmaceutical Use Thereof MAPK1, MAPK13, MAPK6 TBXAS1 679/4885CYP1A2 639/4885USP2 3982/4885
US-10117861-B2 Phenyl derivative S1PR2, S1PR1, S1PR3 TBXAS1 57/4885CYP1A2 899/4885USP2 4205/4885
US-20100221259-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF CXCR4, CXCL12, CXCR3 TBXAS1 319/4885CYP1A2 1368/4885USP2 4607/4885
US-20140330015-A1 PURINONE DERIVATIVE HYDROCHLORIDE BTK, P2RY1, P2RY13 TBXAS1 1032/4885CYP1A2 4054/4885USP2 3695/4885
US-20160311811-A1 HETEROCYCLIC COMPOUND IRAK4, IRAK1, IRAK2 TBXAS1 1815/4885CYP1A2 4355/4885USP2 3205/4885
US-20090030032-A1 Bicyclic Compound, Production and Use Thereof CCR5, CCR1, CCR2 TBXAS1 578/4885CYP1A2 1059/4885USP2 4698/4885
US-10738004-B2 Cyclic compound TLR4, TLR3, TLR1 TBXAS1 4051/4885CYP1A2 3960/4885USP2 3870/4885
US-20190192440-A1 ORAL DRUG DOSAGE FORM COMPRISING DRUG IN THE FORM OF NANOPARTICLES CYP2D6, CYP3A5, CYP3A7 TBXAS1 3657/4885CYP1A2 30/4885USP2 2634/4885
US-10053468-B2 Heterocyclic compound RORC, RORB, RORA TBXAS1 555/4885CYP1A2 526/4885USP2 4448/4885
US-20220002303-A1 DIHYDROPYRROLOPYRAZOLE DERIVATIVE CBR3, SLC13A3, CYP3A5 TBXAS1 1220/4885CYP1A2 34/4885USP2 4853/4885
US-20140296257-A1 High-Loading Water-Soluable Carrier-Linked Prodrugs ABCB11, SLCO1B1, SLC7A1 TBXAS1 1704/4885CYP1A2 240/4885USP2 2210/4885
US-20170050974-A1 HETEROCYCLIC COMPOUND RORC, RORB, RORA TBXAS1 555/4885CYP1A2 526/4885USP2 4448/4885
US-10745397-B2 1-Substituted 1,2,3,4-tetrahydro-1,7-naphthyridin-8-amine derivatives and their use as EP4 receptor antagonists PTGER4, PTGER1, PTGER3 TBXAS1 52/4885CYP1A2 1070/4885USP2 4174/4885
US-20230242529-A1 HETEROCYCLIC COMPOUND XIAP, BIRC5, BIRC3 TBXAS1 3013/4885CYP1A2 3636/4885USP2 1267/4885
US-20140163001-A1 HETEROCYCLIC COMPOUND RORC, RORB, RORA TBXAS1 1141/4885CYP1A2 194/4885USP2 4715/4885
US-20210015933-A1 BIOACTIVE CARBOXYLIC ACID TYPE COMPOUND-POLYMER CONJUGATE, AND METHOD FOR MANUFACTURING THE SAME HCAR1, HCAR2, MCCC2 TBXAS1 2190/4885CYP1A2 1025/4885USP2 794/4885
US-20050020634-A1 Coumarin derivatives, process for their production and use thereof CBR1, ACAT2, CBR3 TBXAS1 1190/4885CYP1A2 240/4885USP2 3628/4885
US-20050124577-A1 8-Azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient PTGER2, PTGIS, HPGDS TBXAS1 773/4885CYP1A2 354/4885USP2 2669/4885
US-20080293764-A1 LPA RECEPTOR ANTAGONIST LPAR1, LPAR2, LPAR4 TBXAS1 864/4885CYP1A2 3432/4885USP2 3605/4885
US-20100249157-A2 LPA RECEPTOR ANTAGONIST LPAR1, LPAR2, LPAR4 TBXAS1 864/4885CYP1A2 3432/4885USP2 3605/4885
US-20200339577-A1 1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS PTGER4, PTGER1, PTGER3 TBXAS1 52/4885CYP1A2 1070/4885USP2 4174/4885
US-10093629-B2 Heterocyclic compounds and their use as retinoid-related orphan receptor (ROR) gamma-T inhibitors RORC, RORB, RORA TBXAS1 761/4885CYP1A2 652/4885USP2 4484/4885
US-20130090482-A1 CRYSTALLINE FORMS OF 4, 4'- [4-FLUORO-7-( ETHYNYL)-2-METHYL-1H-INDOLE-1,3-DIYL] DIBUTANOIC ACID, 4,4'-[2-METHYL-7-( ETHYNYL)-1H-INDOLE-1, 3-DIYL] DIBUTANOIC ACID, AND 4,4'-[4-FLUORO-2-METHYL-7- ( ETHYNYL)-1H-INDOLE-1, 3-DIYL] DIBUTANOIC ACID IDO1, HTR3C, HTR5A TBXAS1 3751/4885CYP1A2 322/4885USP2 2776/4885
US-20190169192-A1 PURINONE DERIVATIVE BTK, KIT, SYK TBXAS1 922/4885CYP1A2 453/4885USP2 2527/4885
US-20120046467-A1 QUATERNARY AMMONIUM SALT COMPOUNDS ADRB2, AGTR2, ADRB3 TBXAS1 1269/4885CYP1A2 621/4885USP2 1907/4885
US-20090042885-A1 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUND AND AGENT COMPRISING THE COMPOUND AS ACTIVE INGREDIENT PTGER2, PTGIS, HPGDS TBXAS1 888/4885CYP1A2 570/4885USP2 3062/4885
US-20260042788-A1 STAT6 COMPOUNDS STAT6, IL6ST, NFATC1 TBXAS1 741/4885CYP1A2 2769/4885USP2 3417/4885
US-20050080113-A1 Medicinal compositions TNF, TRAF6, MMP8 TBXAS1 866/4885CYP1A2 3863/4885USP2 3499/4885
US-10363220-B2 Compartmented pharmaceutical dosage forms CYP2D6, CYP3A5, CYP2F1 TBXAS1 2935/4885CYP1A2 30/4885USP2 3224/4885
US-20190256531-A1 SUBSTITUTED DIHYDROPYRROLOPYRAZOLE DERIVATIVE QDPR, CYP11B2, CYP4F3 TBXAS1 739/4885CYP1A2 45/4885USP2 4823/4885
US-20100284991-A1 Methods for the Treatment and Diagnosis of Bone Mineral Density Related Diseases TBXAS1, TBXA2R, HPGDS TBXAS1 1/4885CYP1A2 1033/4885USP2 4416/4885
US-20170174682-A1 HETEROCYCLIC COMPOUND JAK2, JAK1, STAT3 TBXAS1 888/4885CYP1A2 3676/4885USP2 2218/4885
US-20090131403-A1 NITROGENATED HETEROCYCLIC DERIVATIVE , AND PHARMACEUTICAL AGENT COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT CXCR3, CCR5, HLA-DRB1 TBXAS1 330/4885CYP1A2 1601/4885USP2 4625/4885
US-20160251352-A1 HETEROCYCLIC COMPOUND JAK2, JAK1, STAT3 TBXAS1 1039/4885CYP1A2 3322/4885USP2 1486/4885
US-20100160647-A1 ETHYNYLINDOLE COMPOUNDS CYSLTR2, CYSLTR1, LTB4R2 TBXAS1 338/4885CYP1A2 435/4885USP2 1934/4885
US-20180099000-A1 Method for the Prophylaxis or Treatment of Systemic Lupus Erythematosus and/or Lupus Nephritis SSB, ME1, SLC16A1 TBXAS1 4324/4885CYP1A2 3466/4885USP2 3484/4885
US-20060035865-A1 Lipid-rich plaque regressing agents NR1H2, NR1H3, LDLR TBXAS1 988/4885CYP1A2 1089/4885USP2 3550/4885
US-20100130737-A1 Regulating Agent of GPR34 Receptor Function GPR34, GPR4, GPR6 TBXAS1 2012/4885CYP1A2 3046/4885USP2 3343/4885
US-20040063685-A1 Cycloalkene antisepsis drug with antibacterial, antifungal, nonsteroidal antiinflammatory, steroid and/or anticoagulant agents ELANE, MMP8, SERPINC1 TBXAS1 182/4885CYP1A2 63/4885USP2 3758/4885
US-10869851-B1 Targeting NUR77 for mitigating perinatal neuroinflammation FABP7, NR4A2, NR4A3 TBXAS1 2200/4885CYP1A2 3190/4885USP2 2920/4885
US-20130217880-A1 PURINONE DERIVATIVE BTK, KIT, SYK TBXAS1 922/4885CYP1A2 453/4885USP2 2527/4885
US-20090004278-A1 Enzymatically Crosslinked Protein Nanoparticles DNPEP, CPN1, LNPEP TBXAS1 3359/4885CYP1A2 2936/4885USP2 35/4885
US-20150094296-A1 HETEROCYCLIC COMPOUND TYK2, SSB, UACA TBXAS1 268/4885CYP1A2 2832/4885USP2 2899/4885
US-20090325956-A1 Aromatic amine derivative and use thereof SCD, SCD5, SMS TBXAS1 661/4885CYP1A2 252/4885USP2 4715/4885
US-20200123156-A1 HETEROARYL COMPOUND HAVING DRUG ACTIVITY BTK, LYN, LCK TBXAS1 1999/4885CYP1A2 2222/4885USP2 2009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.