SCHEMBL200675

SCHEMBL200675

CN1C(=O)NC(=O)C(C)(C)C1=O

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
LMNA P02545 2/20 0.40
ATM Q13315 1/20 0.36
ATAD2 Q6PL18 1/20 0.35
PDK2 Q15119 1/20 0.32
PDK4 Q16654 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9337286 0.75 MEN1 (0.40) MEN1KMT2ALMNAATM
SCHEMBL10952021 0.74
Hydrochloric Acid SCHEMBL829197 0.73 MEN1 (0.39) MEN1KMT2ALMNAATM
SCHEMBL15461040 0.72 LMNA (0.39) MEN1KMT2ALMNAATM
SCHEMBL17772669 0.72 PDK2 (0.31) ATAD2PDK2PDK4
SCHEMBL10195453 0.69 LMNA (0.40) MEN1KMT2ALMNA
SCHEMBL11772318 0.69 LMNA (0.40) LMNA
SCHEMBL15458746 0.69
Metharbital SCHEMBL78867 0.69 ATM (0.60) MEN1KMT2ALMNAATM
SCHEMBL14275081 0.68 ATAD2 (0.31) LMNAATAD2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863264-B2 Stabilised compositions having antibacterial activity COLOPLAST A/S (DK) 2011-01-04 US claimed
WO-2008122596-A2 CURABLE THERAPEUTIC IMPLANT COMPOSITION CINVENTION AG (DE) 2008-10-16 WO claimed
US-20080248086-A1 CURABLE THERAPEUTIC IMPLANT COMPOSITION CINVENTION AG (DE) 2008-10-09 US claimed
EP-0438123-B1 Near infrared polymerization initiator SHOWA DENKO KK (JP) 1995-09-13 EP claimed
EP-0438123-A2 Near infrared polymerization initiator SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-07-24 EP claimed
JP-4261405-A None JP disclosed
EP-4032690-B1 MANUFACTURING METHOD FOR A PROSTHETIC APPARATUS AND MANUFACTURING APPARATUS FOR THE PROSTHETIC APPARATUS SHOFU KK (JP) 2025-05-28 EP disclosed
EP-3042645-B2 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2025-03-12 EP disclosed
EP-3479812-B1 RESIN CURED BODY FOR DENTAL CUTTING PROCESSING IMPROVED IN ADHESIVE PROPERTY SHOFU INC (JP) 2025-03-05 EP disclosed
US-12194684-B2 Post-curing method after optical shaping of 3D printer KABUSHIKI KAISHA SHOFU (JP) 2025-01-14 US disclosed
US-20220387264-A1 DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN STORAGE STABILITY SHOFU INC. (JP) 2022-12-08 US disclosed
US-20220347927-A1 POST-CURING METHOD AFTER OPTICAL SHAPING OF 3D PRINTER KABUSHIKI KAISHA SHOFU (JP) 2022-11-03 US disclosed
US-4636453-A Photopolymer films containing microencapsulated sensitometric adjuvants E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-01-13 US disclosed
EP-0103294-B1 N-ALKYLINDOLYLIDENE AND N-ALKYLBENZOTHIAZOLYLIDENE ALKANONES AS SENSITIZERS FOR PHOTOPOLYMER COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-12-30 EP disclosed
US-4565769-A Polymeric sensitizers for photopolymer composition E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-21 US disclosed
US-4555473-A ETHYLENICALLY UNSATURATED MONOMER, PHOTOINITIATOR, BINDER E. I. DUPONT DE NEMOURS AND COMPANY (US) 1985-11-26 US disclosed
US-4535052-A HIGH SPEED PHOTORESISTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-13 US disclosed
EP-0127762-A1 Constrained N-alkylamino aryl ketones as sensitizers for photopolymer compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-12-12 EP disclosed
US-4454218-A WITH UNSATURATED COMPOUND AND PHOTOINITIATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-06-12 US disclosed
EP-0103294-A1 N-alkylindolylidene and N-alkylbenzothiazolylidene alkanones as sensitizers for photopolymer compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220387264-A1 DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN STORAGE STABILITY H1-0, POLA1, H1-2 MEN1 714/4885KMT2A 1832/4885LMNA 92/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.