Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1055708 | 0.83 | ALDH1A1 (0.61) | LMNAALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL28932605 | 0.83 | ALDH1A1 (0.57) | LMNAALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL29265486 | 0.83 | ALDH1A1 (0.53) | LMNAALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL2971851 | 0.82 | LMNA (0.58) | LMNAALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL11769775 | 0.81 | SMN1; SMN2 (0.66) | LMNAALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL9666128 | 0.81 | LMNA (0.56) | LMNAALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6378577 | 0.81 | LMNA (0.56) | LMNAALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL17479491 | 0.81 | LMNA (0.52) | LMNAALDH1A1MAPTSMN1; SMN2NPC1 | |
| Ethyl Benzoate SCHEMBL9248394 | 0.81 | LMNA (0.66) | LMNAALDH1A1MAPTSMN1; SMN2NPC1 | |
| Ethyl Benzoate SCHEMBL25388294 | 0.81 | LMNA (0.70) | LMNAALDH1A1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964637-B2 | Process for producing optically active theaspirane | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20090270516-A1 | Process for Producing Optically Active Theaspirane | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270516-A1 | Process for Producing Optically Active Theaspirane | DHPS, ALDH7A1, FASN | LMNA 2255/4885ALDH1A1 38/4885MAPT 1525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.