Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14957953 | 0.80 | NR4A2 (0.41) | MAPTKMT2AMEN1USP2NR4A2 | |
| SCHEMBL20068336 | 0.72 | MYC (0.49) | MAPTKMT2AMEN1USP2NR4A2 | |
| SCHEMBL21354384 | 0.69 | NR4A2 (0.40) | MAPTKMT2AMEN1USP2NR4A2 | |
| SCHEMBL21354382 | 0.69 | NR4A2 (0.40) | MAPTKMT2AMEN1USP2NR4A2 | |
| SCHEMBL14958413 | 0.69 | ALDH1A1 (0.46) | MAPTKMT2AMEN1USP2NR4A2 | |
| SCHEMBL31186050 | 0.68 | ALDH1A1 (0.52) | MAPTKMT2ANR4A2GAALMNA | |
| SCHEMBL9353793 | 0.67 | NR4A2 (0.67) | MAPTKMT2AMEN1NR4A2GAA | |
| SCHEMBL7347897 | 0.66 | SIGMAR1 (0.43) | MAPTTP53KMT2AMEN1GAA | |
| SCHEMBL14958425 | 0.66 | MAPT (0.39) | MAPTKMT2AMEN1USP2NR4A2 | |
| SCHEMBL14958424 | 0.66 | MAPT (0.39) | MAPTKMT2AMEN1USP2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071535-A1 | PESTICIDAL AND PARASITICIDAL VINYL ISOXAZOLINE COMPOUNDS | MERIAL, INC. (US) | 2018-04-19 | — | — | WO | disclosed |