Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20061078 | 0.92 | GPR119 (0.39) | GPR119NR1H2NR1H3 | |
| SCHEMBL20061055 | 0.88 | GPR119 (0.47) | GPR119NR1H2NR1H3HRH3 | |
| SCHEMBL20060927 | 0.88 | GPR119 (0.47) | GPR119NR1H2NR1H3HRH3 | |
| SCHEMBL20061043 | 0.85 | NR1H2 (0.55) | GPR119NR1H2NR1H3 | |
| SCHEMBL30451102 | 0.85 | NR1H2 (0.55) | GPR119NR1H2NR1H3 | |
| SCHEMBL22311075 | 0.85 | NR1H2 (0.55) | GPR119NR1H2NR1H3 | |
| SCHEMBL22311400 | 0.81 | NR1H2 (0.56) | GPR119NR1H2NR1H3HRH3 | |
| SCHEMBL30452109 | 0.81 | NR1H2 (0.56) | GPR119NR1H2NR1H3HRH3 | |
| SCHEMBL20061074 | 0.81 | NR1H2 (0.56) | GPR119NR1H2NR1H3HRH3 | |
| SCHEMBL20068490 | 0.81 | NR1H2 (0.43) | GPR119NR1H2NR1H3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071317-A1 | ARYL AND HETEROARYL ETHER DERIVATIVES AS LIVER X RECEPTOR BETA AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2018-04-19 | — | — | WO | disclosed |