Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28062586 | 0.92 | SIGMAR1 (0.33) | SIGMAR1MAOAMAOBCHRNB2CHRNA4 | |
| Trifluoroacetic Acid SCHEMBL6513879 | 0.86 | L3MBTL1 (0.32) | — | |
| Bromide SCHEMBL7498281 | 0.70 | MAOA (0.35) | MAOAMAOBCDC25B | |
| SCHEMBL15935159 | 0.69 | — | — | |
| SCHEMBL14907482 | 0.69 | SIGMAR1 (0.36) | SIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL28119106 | 0.67 | MAOA (0.34) | MAOAMAOBCDC25B | |
| SCHEMBL3854986 | 0.67 | SIGMAR1 (0.32) | SIGMAR1MAOAMAOB | |
| SCHEMBL22123082 | 0.62 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL22962411 | 0.61 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL10585695 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194138-A1 | 7H- azulene [1,2,3-i,j] isoquinolin-7-one compound, single crystal and use thereof | UNIV HUNAN CHINESE MEDICINE (CN) | 2019-06-27 | — | — | US | claimed |
| EP-3212634-A1 | COMPOUNDS AND METHODS TO SUPPRESS AUTOIMMUNE RESPONSE | OREGON STATE UNIVERSITY (US) | 2017-09-06 | — | — | EP | claimed |
| WO-2016069780-A1 | COMPOUNDS AND METHODS TO SUPPRESS AUTOIMMUNE RESPONSE | OREGON STATE UNIVERSITY (US) | 2016-05-06 | — | — | WO | claimed |
| EP-2032141-A1 | INHIBITORS OF JANUS KINASES | Merck & Co., Inc. (US) | 2009-03-11 | — | — | EP | claimed |
| WO-2007145957-A1 | INHIBITORS OF JANUS KINASES | MERCK & CO., INC. (US) | 2007-12-21 | — | — | WO | claimed |
| WO-2005105814-A1 | TETRACYCLIC INHIBITORS OF JANUS KINASES | INCYTE CORPORATION (US) | 2005-11-10 | — | — | WO | claimed |
| US-5925336-A | Aqueous nail coating composition containing copolymerized colorants | EASTMAN CHEMICAL COMPANY (US) | 1999-07-20 | — | — | US | claimed |
| US-5744129-A | Aqueous lip gloss and cosmetic compositions containing colored sulfopolyesters | EASTMAN CHEMICAL COMPANY | 1998-04-28 | — | — | US | claimed |
| US-5735907-A | COLORANT REACTED INTO OR ONTO POLYMER BACKBONE | CLAIROL, INC. (US) | 1998-04-07 | — | — | US | claimed |
| EP-0605566-A1 | LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH | EASTMAN CHEMICAL COMPANY (US) | 1994-07-13 | — | — | EP | claimed |
| WO-1993006147-A1 | LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH | EASTMAN KODAK COMPANY (US) | 1993-04-01 | — | — | WO | claimed |
| US-5194463-A | LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH | EASTMAN KODAK COMPANY (US) | 1993-03-16 | — | — | US | claimed |
| JP-52151320-A | — | — | None | — | — | JP | disclosed |
| EP-4688959-A2 | NAPHTHALIMIDE DYES AND USES IN NUCLEIC ACID SEQUENCING | Illumina, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| CN-111527205-B | Novel method for synthesizing polynucleotides using diverse libraries of oligonucleotides | 里本生物实验室有限责任公司 | 2024-12-17 | — | — | CN | disclosed |
| WO-2024206407-A2 | NAPHTHALIMIDE DYES AND USES IN NUCLEIC ACID SEQUENCING | ILLUMINA, INC. (US) | 2024-10-03 | — | — | WO | disclosed |
| US-4618555-A | PHOTOSENSITIVITY; DURABILITY | MITSUBISHI CHEMICAL IND., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| EP-0150707-A1 | Electrophotographic photoreceptor | MITSUBISHI KASEI CORPORATION (JP) | 1985-08-07 | — | — | EP | disclosed |
| EP-0106430-A2 | Isoquinoline derivatives as immuno-regulators | ELI LILLY AND COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |
| JP-S52151320-A | 3,4-DICHLORO-7H-BENZO(DE)-PYRAZOLO(5,1-A)ISOQUINOLINE-7-ONE DERIVATIVE | MITSUBISHI CHEM IND LTD | 1977-12-15 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194138-A1 | 7H- azulene [1,2,3-i,j] isoquinolin-7-one compound, single crystal and use thereof | CALU, CACNA1S, BACE1 | SIGMAR1 3436/4885MAOA 3036/4885MAOB 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.