SCHEMBL20071759

SCHEMBL20071759

Cc1cc2c(cc1C)N(c1ccc3c(ccc4ccccc43)c1)C(C1N(c3ccc4c(ccc5ccccc54)c3)c3cc(C)c(C)cc3N1c1ccc3c(ccc4ccccc43)c1)N2c1ccc2c(ccc3ccccc32)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
CYP1A2 P05177 7/20 0.44
HSD17B10 Q99714 3/20 0.44
HPGD P15428 2/20 0.44
CYP1B1 Q16678 2/20 0.41
HIF1A Q16665 1/20 0.41
HPRT1 P00492 2/20 0.39
GAA P10253 1/20 0.38
RAB9A P51151 1/20 0.38
MAPT P10636 3/20 0.38
CYP1A1 P04798 1/20 0.38
CYP2A6 P11509 4/20 0.38
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
FYN P06241 2/20 0.37
ACHE P22303 2/20 0.37
AHR P35869 2/20 0.37
LCK P06239 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
SLC6A2 P23975 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20071762 0.87 ALDH1A1 (0.47) ALDH1A1CYP1A2HSD17B10HPGDCYP1B1
SCHEMBL19355007 0.87 RAB9A (0.45) ALDH1A1CYP1A2GAARAB9ACYP2A6
SCHEMBL19343017 0.79 ALDH1A1 (0.45) ALDH1A1CYP1A2HSD17B10HPGDCYP1B1
SCHEMBL20071957 0.79 HPRT1 (0.48) ALDH1A1CYP1A2HSD17B10HPGDCYP1B1
SCHEMBL20071979 0.78 ALDH1A1 (0.48) ALDH1A1CYP1A2HSD17B10HPGDCYP1B1
SCHEMBL20072021 0.76 CYP1A2 (0.49) ALDH1A1CYP1A2HSD17B10HPGDRAB9A
SCHEMBL18911918 0.74 ADRB1 (0.46) ALDH1A1CYP1A2HPGDGAARAB9A
SCHEMBL18911912 0.74 RAB9A (0.44) ALDH1A1CYP1A2HSD17B10HPGDGAA
SCHEMBL20071770 0.73 CYP2A6 (0.50) ALDH1A1CYP1A2GAARAB9ACYP2A6
SCHEMBL17786071 0.72 HSP90AA1 (0.46) ALDH1A1CYP1A2HSD17B10HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed