SCHEMBL20071843

SCHEMBL20071843

Cc1cccc2c1N(c1ccc3ccccc3c1)C(C1N(c3ccc4ccccc4c3)c3cccc(C)c3N1c1ccc3ccccc3c1)N2c1ccc2ccccc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 2/20 0.37
CYP1A2 P05177 3/20 0.37
RAB9A P51151 2/20 0.37
CYP2C19 P33261 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
HSP90AA1 P07900 1/20 0.36
CYP2A6 P11509 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 2/20 0.35
GAA P10253 1/20 0.35
HTR3E A5X5Y0 1/20 0.34
HTR3B O95264 1/20 0.34
HTR5A P47898 1/20 0.34
HTR3D Q70Z44 1/20 0.34
HTR3C Q8WXA8 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19355007 0.82 RAB9A (0.45) HTR3ACYP1A2RAB9ACYP2C19SMN1; SMN2
SCHEMBL17786071 0.82 HSP90AA1 (0.46) HTR3ACYP1A2RAB9ACYP2C19SMN1; SMN2
SCHEMBL20071825 0.80 ALDH1A1 (0.33) RAB9ASMN1; SMN2TDP1ALDH1A1GAA
SCHEMBL20072021 0.78 CYP1A2 (0.49) CYP1A2RAB9ASMN1; SMN2CYP3A4CYP2A6
SCHEMBL20071959 0.77 HSP90AA1 (0.40) HTR3ACYP1A2RAB9ACYP2C19SMN1; SMN2
SCHEMBL20072022 0.76 CYP2A6 (0.50) HTR3ACYP1A2RAB9ACYP2C19SMN1; SMN2
SCHEMBL20071770 0.75 CYP2A6 (0.50) HTR3ACYP1A2RAB9ACYP2C19SMN1; SMN2
SCHEMBL20071832 0.74 CYP2A6 (0.48) HTR3ACYP1A2RAB9ACYP2C19SMN1; SMN2
SCHEMBL19343034 0.74 HSP90AA1 (0.44) HTR3ACYP1A2RAB9ACYP2C19SMN1; SMN2
SCHEMBL20071759 0.71 ALDH1A1 (0.44) CYP1A2RAB9ACYP2C19CYP2C9CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed