SCHEMBL20071946

SCHEMBL20071946

CCc1cc(N2c3ccccc3N(c3cc(CC)nc(CC)c3)C2C2N(c3cc(CC)nc(CC)c3)c3ccccc3N2c2cc(CC)nc(CC)c2)cc(CC)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
CHRM1 P11229 1/20 0.32
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
HRH3 Q9Y5N1 1/20 0.31
PKM P14618 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MGLL Q99685 1/20 0.31
KDM4E B2RXH2 1/20 0.30
DDAH1 O94760 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20071947 0.81 SCN10A (0.32)
SCHEMBL20062909 0.76 MAT2A (0.35) MAT2AGRIN2DGRIN3BCHRM1ADRA1D
SCHEMBL20681890 0.76 HCRTR1 (0.35) TDP1KDM4E
SCHEMBL20681888 0.71 HPGD (0.35) KDM4E
SCHEMBL17364348 0.67 GAA (0.41) MGLLKDM4E
SCHEMBL18911911 0.67 SMN1; SMN2 (0.39) MGLLKDM4E
SCHEMBL20071986 0.67 ALDH1A1 (0.42) TDP1KDM4E
SCHEMBL17786071 0.66 HSP90AA1 (0.46) TDP1
SCHEMBL20681874 0.65 LMNA (0.39) TDP1KDM4E
SCHEMBL20072022 0.64 CYP2A6 (0.50) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 MAT2A 3793/4885GRIN2D 61/4885GRIN3B 715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.