SCHEMBL20072080

SCHEMBL20072080

Cc1ccc(N2c3ccccc3N(c3ccc(C)s3)C2C2N(c3ccc(C)s3)c3ccccc3N2c2ccc(C)s2)s1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.33
DRD3 P35462 1/20 0.33
KCNH2 Q12809 1/20 0.33
ALDH1A1 P00352 6/20 0.33
HPGD P15428 4/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
KDM4E B2RXH2 3/20 0.33
HSD17B10 Q99714 2/20 0.33
MAPT P10636 4/20 0.33
KMT2A Q03164 3/20 0.33
THRB P10828 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33
RECQL P46063 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
CASP3 P42574 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062964 0.78 ALDH1A1 (0.33) DRD2DRD3KCNH2ALDH1A1HPGD
SCHEMBL23743459 0.67 TP53 (0.33) DRD2DRD3KCNH2ALDH1A1MAPT
SCHEMBL20072070 0.67 ALDH1A1 (0.33) DRD2DRD3ALDH1A1HPGDSMN1; SMN2
SCHEMBL17061683 0.65 ALDH1A1 (0.43) DRD2DRD3KCNH2ALDH1A1HPGD
SCHEMBL20071965 0.64 USP2 (0.41) ALDH1A1SMN1; SMN2MAPTKMT2ATHRB
SCHEMBL8932231 0.64 KDM4E (0.43) DRD2DRD3KCNH2ALDH1A1HPGD
SCHEMBL20062959 0.64 PTGS1 (0.33) SMN1; SMN2MAPTNPC1RAB9ACASP3
SCHEMBL24715765 0.63
SCHEMBL20071775 0.62 MAPK1 (0.32) KMT2AMAPK1
SCHEMBL6535605 0.62 F10 (0.41) DRD2DRD3KCNH2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 DRD2 8/4885DRD3 10/4885KCNH2 2008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.